Life Sciences

Principles of Neuronal Function and Dysfunction

Module code: C1016
Level 5
15 credits in autumn semester
Teaching method: Lecture
Assessment modes: Coursework, Multiple choice questions

Neuroscience is the study of the nervous system from its structure, molecular and cellular biology and function through to the consequences of its operation, namely behaviour. The aim of this module is to provide you with your first real insight into the detailed workings of the brain and its development through consideration of the fundamental principles of nervous system operation. The module is also an important grounding for those wishing to take its sister module, Neural Circuits.

Topics covered include:

• Signalling and transmission by nerves and synapses
• Neurotransmission and neuromodulation
• Plasticity in the nervous system
• Cellular and molecular basis of learning and memory
• Fundamental disease mechanisms
• Development of the nervous system
• The role of early experience in the development of the visual system
• Methodological approaches to studying fundamental brain processes.

Module learning outcomes

• Systematically identify key principlesof brain function such as: cellular, molecular, and biophysical processes of signalling within and between neurons, fundamental principles of nervous system plasticity, mechanisms of disease-related neuronal dysfunction and methodological approaches used to study these topics.
• Implement problem solving, quantification,and interpretation of experimental evidenceinclassical and contemporary neuroscience.
• Critically assess and integrate ideas from primary literature and develop skillsto present a convincing and original argument in written form.
• Create a well-structured and concise communication of a contemporary neuroscience topic,using presentation software or other relevant programsto create figures.