
Luc Berthouze
Mathematical neuroscience; neurological disorders
We observe disease to understand disease, and translate basic research into better healthcare.” professor mARA CERCIGNANI
Chair in Medical Physics
Neurological disorders affect millions of people worldwide. Despite advances in our understanding and treatment of these disorders, great challenges remain. Research at Sussex Neuroscience brings scientists together with exciting multidisciplinary clinical and translational projects to investigate the onset, progression and treatment of conditions such as dementia, motor neuron disease, epilepsy and neuropathic pain, as well as psychiatric disorders such as anxiety and substance abuse. Our cutting-edge clinical MRI imaging, molecular and genetics approaches help us to identify druggable targets and the disease biomarkers. Collaborative projects with scientists at the Sussex Drug Discovery Centre and the pharmaceutical industry aim to translate this knowledge from bench to bedside and into clinical trials.
Mathematical neuroscience; neurological disorders
DNA strand break repair and neurological disease
Biological mechanisms of affective disorders
Interoception, psychosis and anxiety
Neuropathic pain
Quantitative imaging techniques; biomarkers of disease
Cognitive mechanisms involved in drug addiction
Brain-body interaction, joint hypermobility and chronic pain
Development and disorders of motor neurons
Molecular mechanisms of Motor Neuron Disease
Molecular neuroscience of addiction and neurodegeneration
Antisense transcription and Nitric Oxide signalling in the brain
Developmental adolescent neuroscience
Spatiotemporal statistical modelling; Morphometry and imaging biomarkers
Psychiatry, psychopharmacology and neurochemical imaging