School of Life Sciences

Spencer Lab

Welcome to the Spencer group website.

 

 

Group "us"ie; 1-10-14: LHS JS,

 

 

 

mw

 

New book; out soon!!

 

 

 

I)     funding has been secured for a 1 year research study. We will investigate metal dyshomeostasis in this disease. More to follow.

 

 

II)                           

http://www.worldwidecancerresearch.org/research/projects/spencer-molecular-p53 

AICR funding has been secured! Project started 21-7-14. Dr Bradley Springett (LHS, below, with Gavin Roffe (centre) and Adam Close (RHS) at Pride) joined us from Institute of Cancer Therapeutics, Bradford and has been introduced to a number of local catering and drinks establishments........ Welcome Bradley!

 brad

III) New PhD:

 A Precompetitive Modular Peptidomimetic Toolkit for Targeting PPIs. iCASE. Welcome and good luck Raysa Khan!

az21

 Paper

Microwave-Mediated Synthesis of N-Methyliminodiacetic Acid (MIDA) Boronates. Close,A. J.; Kemmitt,P.; Emmerson, M. K.; Spencer, J. Tetrahedron, 2014, in press. DOI: http://dx.doi.org/10.1016/j.tet.2014.09.044.

 

 

 


 Synthesis of Hybrid Anticancer Agents Based on Kinase and Histone Deacetylase Inhibitors. Patel, H.; Chuckowree, I.; Coxhead, P. Guille, M.; Wang, M.; Zuckermann, A.;  Williams, R. S. B.;  Librizzi, M.; Paranal, R. N.;  Bradner, J. E.; Spencer, J. MedChemComm. 2014, DOI: 10.1039/c4md00211c,accepted, in press.

 

Multifunctional 8-Hydroxyquinoline-Appended Cyclodextrins as New Inhibitors of Metal-Induced Protein Aggregation. Oliveri, V.; Attanasio, F.; Puglisi, A.; Spencer, J.; Vecchio, G. Chem. Eur. J., 2014, 20, 8954-8964.

ACCEPTED AS BACK COVER FOR JOURNAL and highlighted on the ChemistryViews website:

http://www.chemistryviews.org/details/ezine/6193781/Inhibiting_Protein_Aggregation.html