Chemistry

Research

Prof. Geoff Cloke Subject Chair:
Prof. Geoff Cloke

Research in Chemistry spans the traditional areas of inorganic, organic and physical Chemistry as well as more interdisciplinary activities including bioinorganic, and materials chemistry, and nanoscience. Historical strengths in molecular synthesis, computational chemistry and chemical physics have led to the emergence of two main research topics:

Sussex Drug Discovery Centre

Medicinal Chemistry, which has organic synthesis at its core, includes strong links with biochemistry and molecular biology, the Genome Damage and Stability Centre and Brighton and Sussex Medical School. Drug design, synthesis and delivery are key goals in this area.

Energy and Materials Chemistry

Clean fuels and energy seeks functional solutions to the correlated problems of peak oil and carbon emissions. Research towards this goal is focused on inorganic synthesis and small molecule activation, materials modelling and nanostructure fabrication.

The research areas build on the success of the last national research assessment exercise which rated more than 60% of the Chemistry research activity as being world-leading or internationally excellent.

Key to many of the research activities are the excellent facilities provided within Chemistry including a fully equipped NMR suite, a Mass Spectrometry Centre, small molecule and protein X-ray crystallography, nano-labs with scanning tunnelling, electron and atomic force microscopy facilities and a laser-lab supporting ultra-sensitive spectroscopy and single molecule optical microscopy.   

Research in Chemistry is funded by Grants from the EPSRC, the European Research Council, the EU Marie Curie Scheme, the Leverhulme Trust, the Royal Society, and Industry.

Principal investigators and labs

Dr Alaa Abdul-Sada

Nano technology applications in Metabolomic human health and environmental applications.

For more information visit the Abdul-Sada Lab website.

Professor Mark Bagley

Our research interests span the breadth of heterocyclic chemistry, developing new methods for the synthesis of heteroaromatic compounds of biological interest and new properties for heterocyclic drugs and natural products.

For more information visit the Bagley Lab website

Professor Wendy Brown

Our research investigates various aspects of adsorption and reaction on surfaces. The most recent work of our group focuses on using surface science techniques to study reactions on grain surfaces in space. In particular we look at surface processes that are relevant to star forming regions such as the interstellar medium (ISM).

For more information visit the Brown Lab website.

Dr Qiao Chen

Application of Nanomaterials and Nanotechnology.

For more information visit the Chen Lab website.

Dr Hazel Cox

Computational/Theoretical Inorganic Chemistry:
Structure, Reactivity and Spectroscopy of Multiply Charged Metal-Ligand Complexes.

For more information visit the Cox Lab website.

Dr Ian Crossley

Research in the Crossley lab falls broadly under the umbrella of organometallic chemistry and is primarily concerned with the development and study of electronically distinctive molecules at the transition metal / main group interface.

For more information visit the Crossley Lab website.

Professor Geoff Cloke FRS

The Cloke group conducts research the field of synthetic organometallic chemistry, with particular focus on transition metal and f-element complexes, and small molecule activation and functionalisation via reductive transformations.

For more information visit the Cloke Lab website.

Dr Iain Day

Research in the Day laboratory focuses on the development and application of magnetic resonance methods to probe molecular association and aggregation processes.

For more information visit the Day Lab website.

Dr George Kostakis

We are an inorganic chemistry group at University of Sussex. We aim to synthesize molecules using coordination chemistry basic principles. We use a variety of techniques, including solvothermal synthesis, free-air synthesis, gas sorption analysis, X-ray crystallography, spectroscopy..

For more information visit the Kostakis Lab website.

Professor Sir Harry Kroto FRS


For more information visit the Kroto Lab website.

Professor Tony McCaffery

We know that molecular collisions initiate both physical and chemical change.But can we predict the outcome of molecular collisions at the quantum state level accurately and quickly? Over a number of years the McCaffery group performed experiments that revealed a new form of mechanics we had developed was the fastest and most efficient way to calculate changes in quantum state populations resulting from collisions. This has opened up wholly new areas for exploration.

For more information visit the McCaffery Lab website.

Dr Oscar Navarro

Our reseach focuses on the design and synthesis of organometallic complexes of transition metals and their application as catalysts in organic reactions and polymerizations. We have a special interest in highly efficient catalytic multicomponent reactions and the synthesis of conjugated polymers with potential applications in electronic devices. For more information about who we are and what we do, click on the tabs above.

For more information visit the Navarro Lab website.

Professor Ali Nokhodchi

Solid dosage forms, Powder technology, Particle engineering (micro/nano), Dissolution enhancement, Dry powder inhalers, Oral delivery, Controlled release formulations, Pharmaceutical formulations, Solid state analysis

For more information visit the Nokhodchi Lab website.

Professor John Nixon FRS

We have pioneered developments in the field of low-coordinate phosphorus chemistry, and demonstrated that phosphorus has an exception ability to mimic the chemistry of unsaturated carbon.

For more information visit the Nixon Lab website.

Dr Mark Osborne

Research in our lab focuses on the development and application of ultra-sensitive optical techniques for the detection and manipulation of single molecules.

For more information visit the Osborne Lab website.

Dr John Spencer

The Spencer group conducts research on the interface of chemistry and medicinal chemistry, making use of transition metal catalysis and microwave-mediated synthesis where possible.

For more information visit the Spencer Lab website

Dr John Turner

Research in the Turner laboratory covers two broad themes:

  • Discovery of new forms of matter with concommitant exploration of their properties, reactivity and applications
  • Developing a deeper understanding of strongly correlated many body systems through advanced diffraction techniques and analysis

For more information visit the Turner Lab website

Dr Alfredo Vargas

Our research group aims to design and investigate molecules with novel and interesting properties. In particular we are interested in boron-containing compounds and iron(II) and cobalt(II) transition metal complexes. We employ modern computational chemistry techniques, taking advantage of their well established predictive and descriptive capabilities. Our broader interests include functional materials, catalysis, energy storage and medicinal chemistry. In parallel we also pursue research on computational methodology improvement, particularly on the inclusion of the so-called non-dynamic electron correlation. We also collaborate intensively with experimental research groups, providing fundamental insights that are experimentally unobtainable, in order to guide their experiments and to fully understand their results.

For more information visit the Vargas Lab website.

Dr Eddy Viseux

Research in the Viseux group is currently focussing on the development of strategies for the synthesis of complex natural products with interesting biological properties.

For more information visit the Viseux Lab website.

Professor Simon Ward

As part of a major new strategic investment within the School of Life Sciences we are establishing a Translational Drug Discovery Group comprising medicinal chemistry and molecular pharmacology laboratories. This group will play a key role in the School's translational research strategy, creating a vibrant collaboration across the chemical, biological and clinical sciences to translate the fundamental research discoveries within the University into potential new medicines.

For more information visit the Sussex Drug Discovery Centre