Giamas Lab

Bioinformatics

We have built a functional analysis pipeline for proteomic data based on the logic programming paradigm which originated in artificial intelligence. Our pipeline also has access to R's statistical prowess. We have already used this model to analyse SILAC-based proteomics and other experiments of varied designs.

 

                                     Heatmaps generation                                                             Gene-Ontology analysis

Heatmaps of quantified proteins

GO ontology analysis - biological processes

 

 

 

 

 

 

 

 

 

 

 

                    Protein-protein interaction networks                                                         Functional clustering

functional protein–protein interaction networks - STRING                                    Clustering proteins - dendrogram

 

 

 

 

 

 

 

 

 

 

 

 

                             Venn diagrams                                                                                         Km-plotting analysis (clinical)

Venn graph analysis                                                                                               Km plot graph