The Sussex Centre for Consciousness Science was founded in 2010 to unravel the biological basis of consciousness and generate new clinical applications. In the clinical theme of research, the theoretical and basic science within the Centre extends through cognitive and affective neuroscience to preclinical, clinical, and experimental medicine studies. In addition to the work on interoceptive awareness in states of anxiety, two further strands of clinical work focus on disordered consciousness in psychosis, and in Tourette Syndrome.

• In people experiencing a first episode of psychosis, there may be greatly heightened symptoms of dissociation, notably derealisation and depersonalisation. An ongoing clinical neuroimaging programme is underway.
• People with Tourette Syndrome famously experience involuntary tics, associated with a strong urge to move or vocalise. Despite the involuntary nature of tics, people may sometimes be able to consciously suppress them.  A body of research investigating these processes in Tourette Syndrome is in progress.