The GDSC is a research centre investigating the responses of cells to genome damage and their relationship to cancer and other aspects of human disease.
The purpose-built laboratories, funded by the Joint Infrastructure Fund (JIF), the Wolfson Foundation and Sussex University, are located adjacent to the School of Life Sciences, and provide a dynamic and collaborative environment for carrying out state-of -the-art research. Much of this research is supported by the Medical Research Council via a Centre Grant and Programme Grants. The Centre currently houses twenty research groups.
Additional funding bodies:
Most studentships in the GDSC are funded by the MRC, BBSRC, EU and Cancer Research UK studentships. These cover registration, running expenses, travel to an international meeting and a stipend. Eligibility for these studentships depends on the criteria set by the funding bodies.
Studentships available from January and May 2014:
For listings of our 2014 PhD studentships please go to:http://www.sussex.ac.uk/lifesci/about/opportunities/studentships
Research Technician, Ref 490 (Fixed term) for four months. Full time.
Closing date for applications: 14th March 2014. Expected start date: 1st April 2014
Applications are invited for a Research Technician to join the group of Dr. Jessica Downs to study the role of the PBAF chromatin remodelling complex in DNA damage responses.
The applicant is required to have experience of working in a relevant research lab using relevant methodologies, and with clear evidence of working efficiently and productively within a dynamic team, and of producing research data suitable for publication in peer-reviewed journal.
Applicants should also have the ability to multi-task, prioritise work effectively and have good communication skills.
Informal enquiries about the post can be made to Dr Jessica Downs: firstname.lastname@example.org
Research Fellow (Fixed term) Ref 488
Fixed term until 30 September 2016, Full time.
Closing date for applications: 2 April 2014. Expected start date: 1 May 2014
An MRC-funded fix term (until 30th September 2016) Postdoctoral Research Fellow position is immediately available in the laboratory of Prof. Tony Carr to study the mechanisms by which DNA replication is restarted following replication fork collapse in mammalian cells.
The aim of the project is to establish a site-specific replication fork arrest system in human cells based on the well characterised “RTS1” system we have used extensively in fission yeast (i.e. Lambert et al 2005, Cell 121, 689-702; Mizuno 2009, Genes Dev. 23, 2876-2886; Mizuno et al 2012, Nature 493::246-9). Using a model system we have characterised replication fork restart and the consequent genetic instability. We are now interested in extending our analysis to human cells.
Applicants must have a relevant PhD, experience in mammalian cell biology, a background in replication or DNA damage responses, expertise in a range of molecular biology techniques and show evidence of successfully completing research projects.
More information can be obtained informally from Prof Antony Carr e-mail email@example.com