EDGE Lab

Publications

2020-2022

John A., Desai R., Saunders R., Buckman J.E.J., Brown B., Nurock S., Michael S., Ware P., Marchant N.L., Aguirre E., Rio M., Cooper C., Pilling S., Richards M., Gaysina D., & Stott J. Salivary cortisol in longitudinal associations between affective symptoms and midlife cognitive function: a British birth cohort study. Journal of Psychiatric Research, 2022, 151, 217-224. doi.org/10.1016/j.jpsychires.2022.04.007.

Thompson E.J., Ploubidis G.B., Richards M., & Gaysina D.. Life course trajectories of affective symptoms and their early life predictors. Longitudinal and Life Course Studies, 2022, 13(3), 412-431. doi: 10.1332/175795921X16487298020502

Gaysina D., Thompson E.J. Twin Methodology in Psychological Studies. In Oxford Research Encyclopedia of Psychology. Oxford University Press. 2022 Forthcoming

Gaysina D. Chapter Two: Behavioral Genetics. In Peter K. Smith and Craig H. Hart (Eds.) The Wiley-Blackwell Handbook of Childhood Social Development (Third Edition). John Wiley & Sons 2022; 43-60. ISBN 9781119678984

Rozanski, S., Schmidt, A., John, A., & Gaysina, D. Childhood neglect and trajectories of affective symptoms throughout adulthood: A British birth cohort study. Journal of Affective Disorders, 2021, 295, 416–421. doi:10.1016/j.jad.2021.08.021

Mawson, A., & Gaysina, D. Childhood socio-economic position and affective symptoms in adulthood: The role of neglect. Journal of Affective Disorders, 2021, 286, 267-274. doi:10.1016/j.jad.2021.03.007

John, A., Desai, R., Richards, M., Gaysina, D., & Stott, J. Role of cardiometabolic risk in the association between accumulation of affective symptoms across adulthood and mid-life cognitive function: National cohort study. British Journal of Psychiatry, 2021, 218(5), 254-260. doi:10.1192/bjp.2020.123

Tikhomirova T.N., Gaysina D.A., & Malykh S.B. Adaptation of the Russian-language Version of Parental Bonding Instrument (PBI), Sibirskiy Psikhologicheskiy Zhurnal, 2021, (81), 126-142 (In Russian). doi: 10.17223/17267081/81/6

John A., Rusted J., Richards M., & Gaysina D. Bidirectional relation between affective symptoms and cognitive function from middle to late adulthood: a population-based birth cohort study. Aging & Mental Health, 2021, 25(9), 1642-1648. doi: 10.1080/13607863.2020.1758916 

Evans, D., Gaysina, D., & Field, A.P. Internalising symptoms and working memory as predictors of mathematical attainment trajectories across the primary-secondary education transition. Royal Society Open Science, 2020, 7 (5). 1-18. doi: 10.1098/rsos.191433

Bell G., John A., & Gaysina D.. Affective symptoms across the life course and resilience in cognitive function. Annals of Human Biology, 2020, 47(2): 116-124. doi: 10.1080/03014460.2020.1745886.

John A., Rusted J., Richards M., & Gaysina D. Accumulation of affective symptoms and midlife cognitive function: The role of inflammation. Brain, Behavior and Immunity, 2020, 84, 164-172. doi: 10.1016/j.bbi.2019.11.021

2015-2019

John A, James SN, Rusted J, Richards M, Gaysina D. Effects of affective symptoms in adolescence and adulthood on trajectories of cognitive function from middle to late adulthood. Journal of Affective Disorders, 2019, 259: 424-431. doi: 10.1016/j.jad.2019.08.077

John, A., James, S., Patel, U., Rusted, J., Richards, M., & Gaysina, D. Longitudinal associations of affective symptoms with mid-life cognitive function: Evidence from a British birth cohort. British Journal of Psychiatry, 2019, 215(5): 675-682. doi: 10.1192/bjp.2019.24

John A, Patel U, Rusted J, Richards M, Gaysina D. Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis. Psychological Medicine, 2019, 49(3), 353-365. doi.org/10.1017/S0033291718001137

James SN, Davis D, O'Hare C, Sharmaa N, John A, Gaysina D, Hardy R, Kuh D. Lifetime affective problems and later-life cognitive state: over 50 years of follow-up in a British Birth Cohort Study. Journal of Affective Disorders, 2018, 241, 348-355. doi.org/10.1016/j.jad.2018.07.078

Koike S, Gaysina D, Jones PB, Wong A, Richards M. Catechol O-methyltransferase (COMT) functional haplotype is associated with recurrence of affective symptoms: A prospective birth cohort study. Journal of Affective Disorders, 2018, 229, 437-442. doi: 10.1016/j.jad.2017.12.044. [PDF 384.41KB]

Xu MK, Gaysina D, Tsonaka R,  Morin A, Croudace TJ, Barnett J, Duistermaat J, Richards M, & Jones P. Monoamine oxidase A (MAOA) gene and personality traits from late adolescence through early adulthood: a latent variable investigation. Frontiers in Psychology, 2017, 8: 1736. doi: 10.3389/fpsyg.2017.01736. [PDF 864.23KB]

Secinti E, Thompson EJ, Richards M, & Gaysina D. Research Review: Childhood chronic physical illness and adult emotional health–a systematic review and meta‐analysis. Journal of Child Psychology and Psychiatry, 2017, 58(7): 753-769. doi:10.1111/jcpp.12727. [PDF 384.07KB]

Sands A, Thompson EJ, & Gaysina D. Long-term influences of parental divorce on offspring affective disorders: A systematic review and meta-analysis. Journal of Affective Disorders, 2017, 218: 105-114. doi:10.1016/j.jad.2017.04.015. [PDF 562.25KB]

Chu CS, Chow PCK, Cohen-Woods S, Gaysina D, Tang KY, & McGuffin P. The DAOA gene is associated with schizophrenia in the Taiwanese population. Psychiatry Research, 2017, 252, 201-207. [PDF 259.08KB]

Malykh SB, Kovas Y, Gaysina DA. (Eds) Behavioural Genomics: Child Development And Education. Publishing House of Tomsk State University, Tomsk, 2016. 442 pages. ISBN 978-5-94621-585-5 (In Russian). [PDF 5.25MB]

Malykh S, Kovas Y, and Gaysina D. (Eds.) Behavioural Genetics for Education. Palgrave Macmillan, 2016: ISBN 9781137437310. Available online.

Barsky P, and Gaysina D. Gene-environment interplay and individual differences in psychological traits. In Malykh S, Kovas Y, & Gaysina D. (Eds.) Behavioural Genetics for Education. Palgrave Macmillan, 2016. Pp. 24-41.

Rodic M, Gaysina D, Docherty S, Malykh S, Rimfeld K, Plomin R, Kovas Y. Can we use rare genetic syndromes to learn about normal variation in educationally relevant traits? In Malykh S, Kovas Y, & Gaysina D. (Eds.) Behavioural Genetics for Education. Palgrave Macmillan, 2016. Pp. 77-95.

Gindina E, and Gaysina D. Behavioural genetic studies of child and adolescent psychopathology. In Malykh S, Kovas Y, & Gaysina D. (Eds.) Behavioural Genetics for Education. Palgrave Macmillan 2016. Pp. 155-184.

Thompson E, Kazantseva A, Gaysina D. Internalizing psychopathology across the life course: from genes and environment to gene-environment interaction. Psychopathology Review, 2015, 4(1): 26-51. doi: http://dx.doi.org/10.5127/pr.038415

Gaysina D, Richards M, Kuh D, Hardy R. Pubertal maturation and affective symptoms in adolescence and adulthood: evidence from a prospective birth cohort. Development and Psychopathology 2015; 27(4 Pt 1): 1331-1340. doi: 10.1017/S0954579414001448. [PDF 143.21KB]

Xu MK, Gaysina D, Barnett JH, Scoriels L, van de Lagemaat LN, Wong A, Richards M, Croudace TJ, Jones PB, and the LHA genetics group. Psychometric precision in phenotype definition is a useful step in molecular genetic investigation of psychiatric disorders. Translational Psychiatry 2015; 5, e593. doi: 10.1038/tp.2015.86. [PDF 1017.98KB] 

Pina-Camacho L, Jensen SK, Gaysina D, Barker ED. Maternal depression symptoms, unhealthy diet and child emotional-behavioural dysregulation. Psychological Medicine 2015; 45(9): 1851-1860. doi: 10.1017/S0033291714002955. [PDF 194.94KB]

2011-2014

Harold GT, Leve LD, Kim HK, Mahedy L, Gaysina D, Thapar A, Collishaw S. Maternal caregiving and girls’ depressive symptoms and antisocial behavior trajectories: An examination among high-risk youth. Development and Psychopathology 2014; 26(4 Pt 2):1461-1475. doi: 10.1017/S095457941400114X. [PDF 230.52KB]

Kazantseva A, Gaysina D, Kutlumbetova Y, Kanzafarova R, Malykh S, Lobaskova M, Khusnutdinova E. Brain derived neurotrophic factor gene (BDNF) and personality traits: The modifying effect of season of birth and sex. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2014; 56: 58-65. doi: 10.1016/j.pnpbp.2014.08.001. [PDF 631.37KB]

Gaysina D, Gardner MP, Richards M, Ben-Shlomo Y. Cortisol and cognitive function in midlife: the role of childhood cognition and educational attainment. Psychoneuroendocrinology 2014; 47:189-198. doi: 10.1016/j.psyneuen.2014.05.018. [PDF 910.61KB]

Elam KK, Harold GT, Neiderhiser JM, Reiss D, Barrett D, Natsuaki MN, Gaysina D, Shaw DS, Leve LD. Adoptive parent hostility and children’s peer behavior problems: examining the role of genetically-informed child attributes on adoptive parent behavior. Developmental Psychology 2014; 50(5): 1543-1552. doi: 10.1037/a0035470. [PDF 167.09KB]

Richards M, Barnett JH, Xu Man K, Croudace TJ, Gaysina D, Kuh D, Jones PB. Lifetime affect and midlife cognitive function in a prospective birth cohort study. British Journal of Psychiatry 2014; 204:194-9. doi: 10.1192/bjp.bp.113.128942. [PDF 335.50KB]

Xu Man K, Jones PB, Barnett JH, Gaysina D, Kuh D, Croudace TJ, Richards M. Adolescent self-organization predicts midlife memory in a prospective birth cohort study. Psychology and Aging 2013; 28(4): 958-968. doi: 10.1037/a0033787. [PDF 285.02KB]

Gaysina D, Fergusson DM, Leve LD, Horwood J, Reiss D, Shaw DS, Elam KK, Natsuaki MN, Neiderhiser JM, Harold GT. Maternal smoking during pregnancy and offspring conduct problems: evidence from 3 independent genetically sensitive research designs. JAMA Psychiatry 2013; 70(9): 956-963. doi: 10.1001/jamapsychiatry.2013.127. [PDF 210.80KB]

Gaysina D, Xu M, Barnett JH, Croudace T, Wong A, Richards M, Jones PB; the LHA genetics group. The catechol-O-methyltransferase gene (COMT) and cognitive function from childhood through adolescence. Biological Psychology 2013; 92(2): 359-364. doi: 10.1016/j.biopsycho.2012.11.007. [PDF 508.01KB]

Malykh S, Belova A, Sabirova E, Voronin I, Gindina E, Gaysina D. Depressiveness in children and adolescents: a cross-cultural study in Russia and Kyrgyzstan. Procedia - Social and Behavioral Sciences 2013; 86: 53-58. doi: 10.1016/j.sbspro.2013.08.524. [PDF 473.02KB]

Malykh SB, Belova AP, Sabirova EZ, Voronin IA, Bubnova YV, Gubacheva EH, Ismatullina VI, Novgorodova YO, Gindina ED, Gaysina DA. Depression in children and adolescents: Cross-cultural investigation in Russia and Kyrgyzstan. Theoretical and Experimental Psychology 2012; 5(3): 33-41 (in Russian). [PDF 608.25KB]

Khalilova ZL, Zaynullina AG, Gaysina DA, Khusnutdinova EK. Analysis of association between haplotype tryptophan hydroxylase 1 gene and suicidal behaviour. Russian Psychiatric Journal 2012; 1: 57-60 (in Russian). [PDF 200.27KB]

Soler Artigas M, Loth DW, Wain LV, et al. Genome-wide association and large scale follow-up identifies 16 novel loci for lung function. Nature Genetics 2011; 43(11):1082-1090. [PDF 976.09KB]

Gaysina D, Pierce M, Richards M, Hotopf M, Kuh D, Hardy R. Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene polymorphisms. Brain, Behavior, and Immunity 2011; 25(4):750-758. [PDF 262.33KB]

Schosser A, Gaysina D, Cohen-Woods S, Domenici E, Perry J, Tozzi F, Korszun A, Gunasinghe C, Gray J, Jones L, Binder E, Holsboer F, Craddock N, Owen MJ, Craig IW, Farmer AE, Muglia P, McGuffin P. A follow-up case-control association study of tractable (druggable) genes in recurrent major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2011; 156B(6):640-650. [PDF 144.42KB]

Samaan Z, Gaysina D, Cohen S, Hoda F, Craddock N, Korszun A, Owen MJ, Craig IW, McGuffin P, Farmer A, Methylenetetrahydrofolate reductase gene (MTHFR) is associated with migraine with aura in depressive patients. BMC Neurology 2011, 11:66 (2 June 2011). [PDF 309.81KB]

Kazantseva A, Gaysina D, Malykh S, Khusnutdinova E. The role of dopamine transporter (SLC6A3) and dopamine D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) gene polymorphisms in personality traits. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2011, 35(4):1033-1040. [PDF 195.03KB]

Peerbooms OLJ, van Os J , Drukker M,  Kenis G, Hoogveld L, MTHFR in Psychiatry Group (as a member of this group), de Hert M, Delespaul P, van Winkel R, Rutten BPF. Meta-analysis of MTHFR gene variants and schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability? Brain, Behavior, and Immunity 2011; 25(8): 1530–1543. [PDF 1.89MB]

Gaysina D, Hotopf M, Richards M, Colman I, Kuh D, Hardy R. Symptoms of depression and anxiety, and change in body mass index from adolescence to adulthood: results from a British birth cohort. Psychological Medicine 2011; 41(1):175-184. [PDF 312.36KB]

2007-2010

Gaysina D (joint first author), Schosser A, Cohen S, Chow PC, MartucciL, Ball H, Tozzi F, J PerryJ,  MugliaP, Craig IW, Peter McGuffin P, FarmerA. Association of DISC1 and TSNAX genes and affective disorders in the Depression Case-Control (DeCC) and Bipolar Affective Case-Control (BACC) studies. Molecular Psychiatry 2010; 15(8):844-849. [PDF 114.67KB]

Gaysina D, Cohen-Woods S, Chow PC, Martucci L, Schosser A, Ball HA, Tozzi F, Perry J, Muglia P, Craig IW, McGuffin P, Farmer A. Association of the DAOA and DAO genes and bipolar disorder: the results of a Bipolar Case Control Study (BACCS). Bipolar Disorders 2010; 12(5):579-581. [PDF 111.20KB]

Gaysina D, Maughan B, Richards M. Association of reading problems with speech and motor development. Results from a British birth cohort. Developmental Medicine & Child Neurology; 2010; 52(7):680-681. [PDF 58.71KB]

Cohen-Woods S, Craig I, Gaysina D, Gray J, Gunasinghe C, Craddock N, Elkin A, Jones L, Kennedy J, King N, Korszun A, Knight J, Owen M, Parikh SV, Strauss J, Sterne A, Vincent J, McGuffin P, Farmer A. The bipolar association case control (BACC) study and meta-analysis: No association with the 5,10-methylenetetrahydrofolate reductase gene and bipolar disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2010; 153B(7):1298-1304. [PDF 119.00KB]

Schosser A,Pirlo K, Gaysina D, Cohen-Woods S, Schalkwyk L, Elkin A, Korszun A, Gunasinghe C, Gray J, Jones L, Meaburn E, Craddock N, Owen M, Farmer A,Craig I, McGuffin P. Limitations of the pooling approach as applied to whole genome association scans with high-density microarrays. BMC Research Notes 2010; 3:274. [PDF 303.63KB]

Schosser A, Cohen-Woods S, Gaysina D, Chow PC, Martucci L, Farmer A, Korszun A, Gunashinghe C, Gray J, Jones L, Craddock N, Owen MJ, Craig IW, McGuffin P. NRG1 gene in recurrent major depression: No association in a large-scale case-control association study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2010; 153B(1):141-147. [PDF 108.77KB]

Cohen-Woods S, Gaysina D, Craddock N, Farmer A, Gray J, Gunasinghe C, Hoda F, Knight J, Korszun A, Owen M, Sterne A, Craig I, McGuffin P. Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in major depressive disorder. Human Molecular Genetics 2009; 18(8):1504-1509. [PDF 82.20KB]

Gaysina D, Cohen-Woods S, Chow PC, MartucciL, Schosser A, Ball H, Tozzi F, J PerryJ, MugliaP, Craig IW, Peter McGuffin P, FarmerA. Association of Dystrobrevin binding protein 1 gene (DTNBP1) in a Bipolar Case-Control Study (BACCS). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2009; 150B(6): 836-844. [PDF 170.18KB]

Kazantseva AV, Gaysina DA, Malykh SB, Khusnutdinova EK. Role of dopamine transporter gene (DAT1) polymorphisms in personality traits variation. Russian Journal of Genetics 2009; 45(8):974-980. [PDF 188.90KB]

Noskova TG, Kazantseva AV, Gareeva AE, Gaisina DA, Tuktarova SU, Khusnutdinova EK. Association of several polymorphic loci of serotoninergic genes with unipolar depression. Russian Journal of Genetics 2009; 45(6):742-748. [PDF 169.09KB]

Gaysina D, Cohen S, Craddock N, Farmer A, Hoda F, Korszun A, Owen MJ, Craig IW, McGuffin P. No association with the 5,10-methylenetetrahydrofolate reductase gene and major depressive disorder: Results of the depression case control (DeCC) study and a meta-analysis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2008; 147B(6):699-706. [PDF 90.30KB]

Kazantseva A, Gaysina D, Faskhutdinova G, Noskova T, Malykh S, KhusnutdinovaE. Polymorphisms of the serotonin transporter gene (5-HTTLPR, A/G SNP in 5-HTTLPR and STin2 VNTR) and their relation to personality traits in healthy individuals from Russia. Psychiatric Genetics 2008; 18:167-176. [PDF 140.36KB]

Noskova T, Pivac N, Nedic G, Kazantseva A, Gaysina D, Faskhutdinova G, Gareeva A, Khalilova Z, Khusnutdinova E, Kovacic DK, Kovacic Z, Jokic M, Seler DM. Ethnic differences in the serotonin transporter polymorphism (5-HTTLPR) in several European populations. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2008; 32(7):1735-1739. [PDF 211.62KB]

Kazantseva AV, Gaysina DA, Malykh SB, Khusnutdinova EK. Psychobiologic models of personality and search for candidate genes. Medical Genetics 2008; 3:3-12 (in Russian). [PDF 1.86MB]

Faskhutdinova GG, Matveeva NP, Gaysina DA, Noskova TG, Kazanceva AV, Zainullina AG, Pavlov FV, Martyinova TF, Ruchina IL, Podlesnyi EV, Kulichkin SS, Nogovicyina AN, Fedorova SA, Khusnutdinova EK. Analysis of dopamine system genes polymorphisms in Yakut and Chukchi alcohol-dependent patients. Medical Genetics 2008; 4:3-8 (in Russian). [PDF 1.11MB]

Gaysina DA, Khallilova ZL, Khusnutdinova EK. Genetic risk factors of suicidal behaviour. Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 2008; 108 (1):87-91 (in Russian). 

Gaysina DA, Zainullina AG, Kazantseva AV, Jurjev EB, Khusnutdinova EK. The serotonin transporter gene: is it a gender-specific candidate gene for suicidal behavior? In Malykh SB and Torgersen AM (Eds.) Gene, brain, behavior, Oslo, Moscow, 2007.

Before 2007

Gaysina D, Zainullina A, Gabdulhakov R, Khusnutdinova E. The serotonin transporter gene: polymorphism and haplotype analysis in Russian suicide attempters. Neuropsychobiology 2006; 54:70-74. [PDF 121.47KB]

Zaynullina A, Gaysina D, Jurjev E, Khusnutdinova E. Association analysis of polymorphic DNA loci of serotonin neurotransmitter  system with risk of schizophrenia. Medical Genetics 2005; 4(3):123-127 (in Russian).

Gaysina DA, Morozova AA, Asadullin AR, Jurjev E.B., Khusnutdinova EK.Genetic factors in epidemiology and pathogenesis of unipolar depression. Medical Genetics 2005; 12:548-555 (in Russian).

Gaysina DA, Jurjev EB, Gumerova RB, Gabdulhatov RM, Khusnutdinova EK. Association of the dopamine D2 receptor and transporter genes with human aggressive behavior. Medical Genetics 2004; 3(3):145-148 (in Russian).

Zaynullina A, Gaysina D, Jurjev E, Ghabdulhatov R, Gumerova R, Khusnutdinova E. The COMT gene: association with schizophrenia and aggressive behavior. Balkan Journal of Medical Genetics 2004; 7(1&2):51-56. FREE FULL TEXT

Gaysina D, Jurjev E, Gabdulhatov R, Khusnutdinova E. Association study of the serotonin 2A and 1B receptor genes with suicidal behavior in two different populations from Russia. Balkan Journal of Medical Genetics 2003; 6(1&2):51-56. FREE FULL TEXT

Gaysina DA, Jurjev EB, Khusnutdinova EK. Association study of polymorphic loci of serotonergic system with suicidal attempts. Medical Genetics 2003; 2(6):278- 281(translated from Russian). [PDF 355.28KB]