Photo of Penny Jeggo

Penny Jeggo
Professorial Fellow (Genome Damage and Stability)
E:
T: +44 (0)1273 678482 or +44 (0)1273 872859


Research

Studies on DNA double strand break (DSBs) repair and its contribution to human health disorders.

Interplay between DNA DSB repair pathways and the interface with DSB signalling.

Identification of patients displaying radiosensitive severe combined immunodeficiency (RS-SCID). The Jeggo laboratory carries out diagnostic work for such disorders.

Radiation protection -- how cells respond to low doses of radiation -- and particularly the impact of low radiation doses on stem cells.

Causes of microcephalic primordial dwarfism, including Seckel Syndrome and related disorders. What do the known genetic defects (such as ATR mutations or defects in origin licensing proteins) cause microcephaly, bone abnormalities and primordial dwarfism.