Research

Crystallisation Laboratory:
In the laboratory we have three crystallisation robots. For experiments at room temperature, there is an Art Robbins Phoenix (the workhorse of the lab, for experiments with 100-300nl of protein per well) and a Douglas Instruments Oryx8 (for fine pH screening, matrix micro-seeding experiments and low volume experiments (50nl)). The crystallization plates (MRC 2- and 3-well and Douglas Vapour Batch) are stored in RUMED incubators at either 14°C or 20°C. For low temperature experiments there is an Art Robbins Gryphon located in a cold-room held at 6°C, so that plates can be made and stored at the same temperature. Most commercial crystallisation screens are available.

X-Ray Laboratory:
The facility houses two generators, one mainly for protein work consisting of a Rigaku 007HF rotating anode generator, VariMax-HF mirrors, Saturn 944+ CCD detector and Oxford Cryosystems 700 cryostream and the second, for chemical crystallography, an Agilent Gemini Ultra (Mo and Cu radiation) with an Oxford Cryosystem 600.

Training in the use of the equipment is given to undergraduate, postgraduate and postdoctoral researchers.