I am a senior lecturer working on molecular chaperones, especially Hsp90. I seek to understand the structural basis for the maturation and activation of Hsp90 client proteins and the interplay with its associated complexes. I use structural, biochemical and genetic techniques to achieve my aims. I have a number of collaborations with staff across the university in helping them understand the molecular basis of interactions within their systems.

I am also actively engaged in programs aimed at the discovery and development of novel small-molecule inhibitors with application as drugs for the treatment of cancer, infectious disease and Alzheimer's disease.