Penn Lab


UPDATE! Check out our new publication:

Elmasri M, Hunter DW, Winchester G, Bates EE, Aziz W, Van Der Does DM, Karachaliou E, Sakimura K, Penn AC. (2022) Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A. Commun Biol. 5(1):174. doi: 10.1038/s42003-022-03115-3.


Elmasri, Marwa, Hunter, Daniel William, Winchester, Giles, Bates, Ella Emine, Aziz, Wajeeha, Van Der Does, Does Moolenaar, Karachaliou, Eirini, Sakimura, Kenji and Penn, Andrew Charles (2022) Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A. Communications Biology, 5 (1). a174 1-17. ISSN 2399-3642

Elmasri, Marwa, Lotti, James S, Aziz, Wajeeha, Steele, Oliver G, Karachaliou, Eirini, Sakimura, Kenji, Hansen, Kasper B and Penn, Andrew C (2022) Synaptic dysfunction by mutations in GRIN2B: influence of triheteromeric NMDA receptors on gain-of-function and loss-of-function mutant classification. Brain Sciences, 12 (6). 789 1-24. ISSN 2076-3425

Steele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine and King, Sarah (2022) A multi-hit hypothesis for an APOE4-dependent pathophysiological state. Eur J Neurosci. ISSN 0953-816X

Penn, A C, Zhang, C L, Georges, F, Royer, L, Breillat, C, Hosy, E, Petersen, J D, Humeau, Y and Choquet, D (2017) Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors. Nature, 549. pp. 384-388. ISSN 0028-0836

Hafner, Anne-Sophie, Penn, Andrew C, Grillo-Bosch, Dolors, Retailleau, Natacha, Poujol, Christel, Philippat, Amandine, Coussen, Françoise, Sainlos, Matthieu, Opazo, Patricio and Choquet, Daniel (2015) Lengthening of the stargazin cytoplasmic tail increases synaptic transmission by promoting interaction to deeper domains of PSD-95. Neuron, 86 (2). pp. 475-489. ISSN 0896-6273

Constals, Audrey, Penn, Andrew C, Compans, Benjamin, Toulmé, Estelle, Phillipat, Amandine, Marais, Sébastien, Retailleau, Natacha, Hafner, Anne-Sophie, Coussen, Françoise, Hosy, Eric and Choquet, Daniel (2015) Glutamate-induced AMPA receptor desensitization increases their mobility and modulates short-term plasticity through unbinding from stargazin. Neuron, 85 (4). pp. 787-803. ISSN 0896-6273

Letellier, Mathieu, Elramah, Sara, Mondin, Magali, Soula, Anaïs, Penn, Andrew, Choquet, Daniel, Landry, Marc, Thoumine, Olivier and Favereaux, Alexandre (2014) miR-92a regulates expression of synaptic GluA1-containing AMPA receptors during homeostatic scaling. Nature Neuroscience, 17 (8). pp. 1040-1042. ISSN 1097-6256

Penn, Andrew C, Balik, Ales and Greger, Ingo H (2013) Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system. Frontiers in Neuroscience, 7 (61). ISSN 1662-4548

Balik, Ales, Penn, Andrew C, Nemoda, Zsofia and Greger, Ingo H (2013) Activity-regulated RNA editing in select neuronal subfields in hippocampus. Nucleic Acids Research, 41 (2). pp. 1124-1134. ISSN 0305-1048

Penn, Andrew C, Balik, Ales and Greger, Ingo H (2013) Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing. Nucleic Acids Research, 41 (2). pp. 1113-1123. ISSN 0305-1048

Penn, Andrew C, Balik, Ales, Wozny, Christian, Cais, Ondrej and Greger, Ingo H (2012) Activity-mediated AMPA receptor remodeling, driven by alternative splicing in the ligand-binding domain. Neuron, 76 (3). pp. 503-510. ISSN 0896-6273

Sukumaran, Madhav, Penn, Andrew C and Greger, Ingo H (2012) AMPA receptor assembly: atomic determinants and built-in modulators. Advances in Experimental Medicine and Biology, 970. pp. 241-264. ISSN 0065-2598

Rossmann, Maxim, Sukumaran, Madhav, Penn, Andrew C, Veprintsev, Dmitry B, Babu, M Madan and Greger, Ingo H (2011) Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers. EMBO Journal, 30 (5). pp. 959-971. ISSN 0261-4189

Penn, Andrew C, Williams, Stephen R and Greger, Ingo H (2008) Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum. EMBO Journal, 27 (22). pp. 3056-3068. ISSN 0261-4189

Greger, Ingo H, Ziff, Edward B and Penn, Andrew C (2007) Molecular determinants of AMPA receptor subunit assembly. Trends in Neurosciences, 30 (8). pp. 407-416. ISSN 0166-2236

Hackney, Caroline M, Mahendrasingam, Shanthini, Penn, Andrew and Fettiplace, Robert (2005) The concentrations of calcium buffering proteins in mammalian cochlear hair cells. Journal of Neuroscience, 25 (34). pp. 7867-7875. ISSN 0270-6474