News

Illustration of part of the human protein–protein interaction network. Proteins are shown as circles, and the connecting lines represent physical interactions. In cancer cells, these connections can change, rewiring the network.

The Pearl AI team are collaborating with the Cancer of Unknown Primary (CUP) teams at several hospitals in Sussex and London to explore how Artificial Intelligence (AI) can be used to find personalised treatment targets for patients whose cancer’s primary site is difficult to determine.

Cancer treatment is usually based on where the tumour starts in the body – but in CUP cases, the origin cannot be identified.

This makes treatment decisions challenging and often leaves patients with limited options and poorer outcomes.

By combining powerful AI tools, rapid cancer genome sequencing, and a unique “bench-to-bedside” research team across Sussex, this project aims to explore ways to transform how these difficult-to-treat cancers are managed and improve patient outcomes.

Back to news list