Selected publications

Article

Legan, Kevin, Goodyear, Richard, Morin, Matias, Mencia, Angeles, Pollard, Hilary, Olavarrieta, Leticia, Korchagina, Julia Jurievna, Modiamo-Hoybjor, Silvia, Mayo, Fernando, Moreno, Felipe, Moreno-Pelayo, Miguel-Angel and Richardson, Guy (2014) Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane. Human Molecular Genetics, 23 (10). pp. 2551-2568. ISSN 0964-6906

Lukashkin, Andrei N, Legan, P Kevin, Weddell, Thomas D, Lukashkina, Victoria A, Goodyear, Richard J, Welstead, Lindsey J, Petit, Christine, Russell, Ian J and Richardson, Guy P (2012) A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation. Proceedings of the National Academy of Sciences of the United States of America, 109 (47). pp. 19351-19356. ISSN 1091-6490

Zheng, Jing, Miller, Katharine K., Yang, Tao, Hildebrand, Michael S., Shearer, A. Eliot, DeLuca, Adam P., Scheetz, Todd E., Drummond, Jennifer, Scherer, Steve E., Legan, P Kevin, Goodyear, Richard J, Richardson, Guy P, Cheatham, Mary Ann, Smith, Richard J. and Dallos, Peter (2011) Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4). Proceedings of the National Academy of Sciences, 108 (10). pp. 4218-4223.

Nayak, Gowri, Goodyear, Richard J, Legan, P Kevin, Noda, Masaharu and Richardson, Guy P (2011) Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear. Developmental Neurobiology, 71 (2). pp. 129-141.

Goodyear, Richard J, Legan, P Kevin, Christiansen, Jeffrey R, Xia, Bei, Korchagina, Julia, Gale, Jonathan E, Warchol, Mark E, Corwin, Jeffrey T and Richardson, Guy P (2010) Identification of the Hair Cell Soma-1 Antigen, HCS-1, as Otoferlin. Journal of the Association for Research in Otolaryngology, 11 (4). pp. 573-586. ISSN 1525-3961

Goodyear, Richard J, Forge, Andy, Legan, P Kevin and Richardson, Guy P (2010) Asymmetric Distribution of Cadherin 23 and Protocadherin 15 in the Kinocilial Links of Avian Sensory Hair Cells. Journal of Comparative Neurology, 518 (21). pp. 4288-4297. ISSN 0021-9967

Moreno-Pelayo, Miguel Ángel, Goodyear, Richard J, Mencía, Ángeles, Modamio-Høybjør, Silvia, Legan, P Kevin, Olavarrieta, Leticia, Moreno, Felipe and Richardson, Guy P (2008) Characterization of a spontaneous, recessive, missense mutation arising in the Tecta gene. Journal of the Association for Research in Otolaryngology, 9 (2). pp. 202-214. ISSN 1525-3961

Ahmed, Zubair M, Goodyear, Richard, Riazuddin, Saima, Lagziel, Ayala, Legan, P Kevin, Behra, Martine, Burgess, Shawn M, Lilley, Kathryn S, Wilcox, Edward R, Riazuddin, Sheikh, Griffith, Andrew J, Frolenkov, Gregory I, Belyantseva, Inna A, Richardson, Guy P and Friedman, Thomas B (2006) The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15. Journal of Neuroscience, 26 (26). pp. 7022-7034. ISSN 0270-6474

Lukashkin, A N, Lukashkina, V A, Legan, P K, Richardson, G P and Russell, I J (2004) Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta(deltaENT/deltaENT) mice. Journal of Neurophysiology, 91 (1). pp. 163-71. ISSN 0022-3077

Goodyear, R J, Legan, P K, Wright, M B, Marcotti, W, Oganesian, A, Coats, S A, Booth, C J, Kros, C J, Seifert, R A, Bowen-Pope, D F and Richardson, G P (2003) A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. Journal of Neuroscience, 23 (27). pp. 9208-9219. ISSN 0270-6474

Legan, P Kevin, Lukashkina, Victoria A, Kössl, Manfred, Goodyear, Richard J, Russell, Ian J and Richardson, Guy P (2000) A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback. Neuron, 28 (1). pp. 273-285. ISSN 08966273

Kruger, Robert P, Goodyear, Richard J, Legan, P Kevin, Warchol, Mark E, Raphael, Yehoash, Cotanche, Douglas A and Richardson, Guy P (1999) The supporting-cell antigen: a receptor-like protein tyrosine phosphatase expressed in the sensory epithelia of the inner ear. Journal of Neuroscience, 19 (12). pp. 4815-4827. ISSN 0270-6474

Coutinho, P, Goodyear, R, Legan, P K and Richardson, G P (1999) Chick a-tectorin: Molecular cloning and expression during embryogenesis. Hearing Research, 130 (1-2). pp. 62-74. ISSN 03785955

Rau, A, Legan, P K and Richardson, G P (1999) Tectorin mRNA is spatially and temporally restricted during mouse inner ear development. Journal of Comparative Neurology, 405 (2). pp. 271-280. ISSN 0021-9967

Van Laer, Lut, Huizing, Egbert H, Verstreken, Margriet, van Zuijlen, Diederick, Wauters, Jan G, Bossuyt, Paul J, Van de Heyning, Paul, McGuirt, Wyman T, Smith, Richard J H, Willems, Patrick J, Legan, P Kevin, Richardson, Guy P and Van Camp, Guy (1998) Nonsyndromic hearing impairment is associated with a mutation in DFNA5. Nature Genetics, 20 (2). pp. 194-7.

Hughes, David C, Legan, P Kevin, Steel, Karen P and Richardson, Guy P (1998) Mapping of the alpha-tectorin gene (TECTA) to mouse chromosome 9 and human chromosome 11: a candidate for human autosomal dominant nonsyndromic deafness. Genomics, 48 (1). pp. 46-51. ISSN 08887543

Rau, A, Legan, P K and Richardson, G P (1998) Expression of tectorin mRNAs during mouse inner ear development. British Journal of Audiology, 32 (2). pp. 73-74. ISSN 03005364

Verhoeven, Kristien, Van Laer, Lut, Kirschhofer, Karin, Legan, P Kevin, Hughes, David C, Schatteman, Isabelle, Verstreken, Margriet, Van Hauwe, Peter Van, Coucke, Paul, Chen, Achih, Smith, Richard J H, Somers, Thomas, Offeciers, F Erwin, Van de Heyning, Paul, Richardson, Guy P, Wachtler, Franz, Kimberling, William J, Willems, Patrick J, Govaerts, Paul J and Van Camp, Guy (1998) Mutations in the human a-tectorin gene cause autosomal dominant non- syndromic hearing impairment. Nature Genetics, 19 (1). pp. 60-62. ISSN 10614036

Legan, P K and Richardson, G P (1997) Extracellular matrix and cell adhesion molecules in the developing inner ear. Seminars in Cell and Developmental Biology, 8 (3). pp. 217-224. ISSN 1084-9521

Legan, P Kevin, Rau, Angela, Keen, Jeff N and Richardson, Guy P (1997) The mouse tectorins: modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system. Journal of Biological Chemistry, 272 (13). pp. 8791-8801. ISSN 00219258

Goodyear, R, Killick, R, Legan, P K and Richardson, G P (1996) Distribution of beta-tectorin mRNA in the early posthatch and developing avian inner ear. Hearing Research, 96 (1-2). pp. 167-78.

Killick, R, Legan, P K, Malenczak, C and Richardson, G P (1995) Molecular cloning of chick beta-tectorin, an extracellular matrix molecule of the inner ear. Journal of Cell Biology, 129 (2). pp. 535-547. ISSN 0021-9525