Environment, Development,

 Genetics & Epigenetics

 in Psychopathology Lab 


At EDGE Lab, we investigate environmental, developmental, genetic, and epigenetic factors, and their interplay, in relation to psychopathology. Specifically, our research focuses on pathways and mechanisms of vulnerability and resilience for affective psychopathology, such as depression and anxiety. Moreover, we explore the links between affective psychopathology and physical and cognitive health and ageing. Our research is truly interdisciplinary; we use prospective longitudinal, cross-cultural, and genetically informative approaches to get insights into determinants and consequences of affective psychopathology across the life course, generations and cultures. 

Research Themes


Our new publications on long-term effects of early adversities on mental health

Sands, A., Thompson, E. J., & Gaysina, D. Long-term influences of parental divorce on offspring affective disorders: A systematic review and meta-analysis. Journal of Affective Disorders, 2017, 218:105-114. doi:10.1016/j.jad.2017.04.015. [pdfinewspaper

*This study is featured in our opinion article 'Are your parents to blame for your psychological problems?' (Darya Gaysina & Ellen J Thompson) published in the Conversation.

** Republished by i Newspaper: 'Don't blame the parents'


Secinti, E., Thompson, E. J., Richards, M., & Gaysina, D. (2017). Research Review: Childhood chronic physical illness and adult emotional health–a systematic review and meta‐analysis. Journal of Child Psychology and Psychiatry, 2017, Published online, doi:10.1111/jcpp.12727. [pdf] [infographics]

*You can also read about this study in the Sussex Blog and the Surg Blog.

**The study has received worldwide media coverage.


OblozhkaOur Russian book companion for 'Behavioural Genetics for Education' (Eds: Kovas, Malykh, Gaysina) is now published (in Russian)

Malykh, S.B., Kovas, Y., Gaysina, D.A. (Eds) (2016). Behavioural Genomics: Child Development And Education. Publishing House of Tomsk State University, Tomsk. 442 pages. ISBN 978-5-94621-585-5 [pdf]


RT @Kingspsychol: #Childhood #abuse & #psychotic experiences-evidence for mediation by adulthood adverse life events cambridge.org/core/journals/… NEW @KingsIoPPN

@tonyrobertson82 @SLLShome @StirUni @camerondawn1 @Stir_PubHealth @draWLAsh @DrJenniCo @StirCourtHotel Thanks for o… twitter.com/i/web/status/9…

And this is so important when studying childhood adversities #ACE and #mentalhealth twitter.com/CLOSER_UK/stat…

More #slls2017 talks on #ACE and lifespan outcomes, & some interesting ideas on #resilience to finish on a positive… twitter.com/i/web/status/9…

RT @shell_ki: Thought provoking work on resilience pathways & child adversities by @edge_lab this morning at #slls2017

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