Baxter Lab

Publications

Article

Westhorpe, Rose, Keszthelyi, Andrea, Minchell, Nicola E, Jones, David and Baxter, Jonathan (2020) Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress. Nucleic Acids Research, 48 (21). pp. 12169-12187. ISSN 0305-1048

Minchell, Nicola Elizabeth, Keszthelyi, Andrea and Baxter, Jonathan (2020) Cohesin causes replicative DNA damage by trapping DNA topological stress. Molecular cell, 78 (4). pp. 739-751. ISSN 1097-2765

Paldi, Flora, Alver, Bonnie, Robertson, Daniel, Schalbetter, Stephanie A, Kerr, Alastair, Kelly, David A, Baxter, Jonathan, Neale, Matthew J and Marston, Adele L (2020) Convergent genes shape budding yeast pericentromeres. Nature, 582. pp. 119-123. ISSN 0028-0836

Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P and Labib, Karim P M (2019) Pif1-Family helicases support fork convergence during DNA replication termination in eukaryotes. Molecular Cell, 74 (2). 231-244.e9. ISSN 1097-4164

Baxter, Jonathan, Oliver, Antony W and Schalbetter, Stephanie A (2019) Are SMC complexes loop extruding factors? Linking theory with fact. BioEssays, 41 (1). 1800182 1-10. ISSN 1521-1878

Schalbettertter, Stephanie Andrea, Goloborodko, Anton, Fudenberg, Geoffrey, Belton, Jon-Matthew, Miles, Catrina, Yu, Miao, Dekker, Job, Mirny, Leonid and Baxter, Jonathan (2017) SMC complexes differentially compact mitotic chromosomes according to genomic context. Nature Cell Biology, 19 (9). pp. 1071-1080. ISSN 1465-7392

Keszthelyi, Andrea, Minchell, Nicola and Baxter, Jon (2016) The causes and consequences of topological stress during DNA replication. Genes, 7 (12). p. 134. ISSN 2073-4425

Schalbetter, Stephanie A, Mansoubi, Sahar, Chambers, Anna L, Downs, Jessica A and Baxter, Jonathan (2015) Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability. Proceedings of the National Academy of Sciences, 112 (33). E4565-E4570. ISSN 0027-8424

Baxter, Jonathan (2014) “Breaking up is hard to do”: the formation and resolution of sister chromatid intertwines. Journal of Molecular Biology, 427 (3). pp. 590-607. ISSN 0022-2836

Baxter, Jon (2012) A model for chromosome condensation based on the interplay between condensin and topoisomerase II. Trends in Genetics, 28 (3). pp. 110-117. ISSN 0168-9525

Baxter, J, Sen, N, López Martínez, V, Monturus De Carandini, M E, Schwartzman, J B, Diffley, J F X and Aragón, L (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science, 331 (6022). pp. 1328-32. ISSN 0036-8075

Baxter, J and Aragón, L (2011) Physical Linkages between Sister Chromatids and Their Removal during Yeast Chromosome Segregation. Cold Spring Harbor Symposia on Quantitative Biology. ISSN 0091-7451

Baxter, Jonathan and Diffley, John F X (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Molecular Cell, 30 (6). pp. 790-802. ISSN 1097-2765

 

Baxter, J.*, Sen, N., Martinez, V.L., De Carandini, M.E., Schvartzman, J.B., Diffley, J.F., and Aragon, L.* (2011). Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science 331, 1328-1332.

 

Baxter, J. and Aragon, L.* (2011). Physical Linkages between Sister Chromatids and Their Removal during Yeast Chromosome Segregation. Cold Spring Harb Symp Quant Biol. Jan 5.

 

Baxter, J. and Diffley, J.F.* (2008). Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Molecular cell 30, 790-802.

 

Baxter, J., Sauer, S., Peters, A., John, R., Williams, R., Caparros, M.L., Arney, K., Otte, A., Jenuwein, T., Merkenschlager, M. and Fisher, A.G* (2004). Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes. The EMBO journal 23, 4462-4472.

 

Baxter, J., Merkenschlager, M. and Fisher, A.G. (2002). Nuclear organisation and gene expression. Current Opinions in Cell Biology 14, 372-376.

 

Mak, W., Baxter, J., Silva, J., Newall, A.E., Otte, A.P. and Brockdorff, N.* (2002). Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells. Current Biology 12, 1016-1020.

 

Skok, J.A., Brown, K.E., Azuara, V., Caparros, M.L., Baxter, J., Takacs, K., Dillon, N., Gray, D., Perry, R.P., Merkenschlager, M. and Fisher, A.G.* (2001). Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. Nature Immunology 2, 848-854.

 

Brown, K.E., Baxter, J., Graf, D., Merkenschlager, M. and Fisher, A.G.* (1999). Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Molecular cell 3, 207-217.

Article

Westhorpe, Rose, Keszthelyi, Andrea, Minchell, Nicola E, Jones, David and Baxter, Jonathan (2020) Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress. Nucleic Acids Research, 48 (21). pp. 12169-12187. ISSN 0305-1048

Minchell, Nicola Elizabeth, Keszthelyi, Andrea and Baxter, Jonathan (2020) Cohesin causes replicative DNA damage by trapping DNA topological stress. Molecular cell, 78 (4). pp. 739-751. ISSN 1097-2765

Paldi, Flora, Alver, Bonnie, Robertson, Daniel, Schalbetter, Stephanie A, Kerr, Alastair, Kelly, David A, Baxter, Jonathan, Neale, Matthew J and Marston, Adele L (2020) Convergent genes shape budding yeast pericentromeres. Nature, 582. pp. 119-123. ISSN 0028-0836

Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P and Labib, Karim P M (2019) Pif1-Family helicases support fork convergence during DNA replication termination in eukaryotes. Molecular Cell, 74 (2). 231-244.e9. ISSN 1097-4164

Baxter, Jonathan, Oliver, Antony W and Schalbetter, Stephanie A (2019) Are SMC complexes loop extruding factors? Linking theory with fact. BioEssays, 41 (1). 1800182 1-10. ISSN 1521-1878

Schalbettertter, Stephanie Andrea, Goloborodko, Anton, Fudenberg, Geoffrey, Belton, Jon-Matthew, Miles, Catrina, Yu, Miao, Dekker, Job, Mirny, Leonid and Baxter, Jonathan (2017) SMC complexes differentially compact mitotic chromosomes according to genomic context. Nature Cell Biology, 19 (9). pp. 1071-1080. ISSN 1465-7392

Keszthelyi, Andrea, Minchell, Nicola and Baxter, Jon (2016) The causes and consequences of topological stress during DNA replication. Genes, 7 (12). p. 134. ISSN 2073-4425

Schalbetter, Stephanie A, Mansoubi, Sahar, Chambers, Anna L, Downs, Jessica A and Baxter, Jonathan (2015) Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability. Proceedings of the National Academy of Sciences, 112 (33). E4565-E4570. ISSN 0027-8424

Baxter, Jonathan (2014) “Breaking up is hard to do”: the formation and resolution of sister chromatid intertwines. Journal of Molecular Biology, 427 (3). pp. 590-607. ISSN 0022-2836

Baxter, Jon (2012) A model for chromosome condensation based on the interplay between condensin and topoisomerase II. Trends in Genetics, 28 (3). pp. 110-117. ISSN 0168-9525

Baxter, J, Sen, N, López Martínez, V, Monturus De Carandini, M E, Schwartzman, J B, Diffley, J F X and Aragón, L (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science, 331 (6022). pp. 1328-32. ISSN 0036-8075

Baxter, J and Aragón, L (2011) Physical Linkages between Sister Chromatids and Their Removal during Yeast Chromosome Segregation. Cold Spring Harbor Symposia on Quantitative Biology. ISSN 0091-7451

Baxter, Jonathan and Diffley, John F X (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Molecular Cell, 30 (6). pp. 790-802. ISSN 1097-2765