Life Sciences

Regulating Gene Expression

Module code: C7132L6
Level 6
15 credits in autumn semester
Teaching method: Lecture, Seminar
Assessment modes: Computer based exam, Coursework

On this module, you’ll take a current perspective on the molecular mechanisms that control RNA expression in eukaryotes.

You’ll focus on:

  • gene transcription and translation
  • RNA processing and regulation by non-coding RNAs
  • post-transcriptional control of genes
  • the translation of protein.

You’ll also explore the effect of eukaryotic transcriptional regulators on:

  • the recruitment and retention of RNA polymerase
  • the chromatin structure during transcriptional activation and repression.

By exploring these processes, you’ll understand how normal cell growth can be deregulated in diseases like cancer.

Module learning outcomes

  • Develop a systematic understanding of the fundamental principles and advanced concepts in gene expression regulation and non-coding RNA activity, integrating coherent and detailed knowledge from the forefront of current research in the field.
  • Acquire proficiency in deploying accurately established techniques of analysis and inquiry within the discipline of gene expression regulation, demonstrating the ability to critically assess research methodologies and experimental approaches.
  • Develop a deep conceptual understanding that enables to formulate sophisticated arguments, solve complex problems, and engage in advanced discussion using cutting-edge ideas and techniques from the discipline of regulating gene expression.
  • Enhance the ability to autonomously employ effective strategies to understand and contextualise peer-reviewed research articles and review articles. Develop the skills to critically evaluate and synthesise information from diverse sources, including original materials pertinent to this discipline