Regulating the Transcriptome (C7132)

15 credits, Level 6

Autumn teaching

This module takes an up-to-the-minute look at the molecular mechanisms controlling RNA expression in prokaryotes and eukaryotes, focusing largely on gene transcription but also examining RNA processing events in eukaryotes.

We will examine the way in which bacteria control gene expression in response to different environmental cues through precisely coordinated transcription regulatory networks, and investigate the way in which eukaryotic transcriptional regulators control RNA polymerase recruitment and retention and modulate chromatin structure during transcriptional activation and repression.

Understanding these processes and mechanisms is fundamental for the study of health and disease, for example to aid the development of new antibiotics and decipher how gene regulatory networks are perturbed during cancer development.

Teaching and assessment

We’re currently reviewing teaching and assessment of our modules in light of the COVID-19 situation. We’ll publish the latest information as soon as possible.

Contact hours and workload

This module is approximately 150 hours of work. This breaks down into about 32 hours of contact time and about 118 hours of independent study. The University may make minor variations to the contact hours for operational reasons, including timetabling requirements.

This module is running in the academic year 2021/22. We also plan to offer it in future academic years. However, there may be changes to this module in response to COVID-19, or due to staff availability, student demand or updates to our curriculum. We’ll make sure to let our applicants know of material changes to modules at the earliest opportunity.

It may not be possible to take some module combinations due to timetabling constraints. The structure of some courses means that the modules you choose first may determine whether later modules are core or optional.

Courses

This module is offered on the following courses: