Postdoctoral Research Fellow-3D genome organization in DNA repair Ref 21060
School/department: School of Life Sciences / Genome Damage and Stability Centre
Hours: Full-time or part-time hours considered up to a maximum of 1.0 FTE. Requests for flexible working options will be considered (subject to business need).
Location: Brighton, United Kingdom
Contract: fixed term until 31 July 2026
Reference: 21060
Salary: starting at £36,333 to £43,155 per annum, pro rata if part time.
Placed on: 26 June 2023.
Closing date: 24 July 2023. Applications must be received by midnight of the closing date.
Expected Interview date: To be confirmed.
Expected start date: 01 September 2023
Job description
The School of Life Sciences at the University of Sussex is at the forefront of research in the UK. In the recent Research Excellence Framework assessment (REF 2021), 100% of our Impact cases in Biological Sciences and Chemistry were rated as world-leading or internationally excellent. The School has received substantial recent University investment and is embarking on an exciting and extensive, multi-million pound refurbishment and improvement project.
Based in the School of Life Sciences, the Genome Damage and Stability Centre (http://www.sussex.ac.uk/gdsc/), is an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability, and its relationship to disease. We provide a stimulating and supportive environment and our expertise covers a range of experimental systems.
Motivated applicants are invited to apply for a BBSRC-funded postdoctoral position to study the impact of DNA damage on epigenome restoration and the interplay with DNA fidelity in stem cells (mES cells and human IPs). We will investigate whether DNA damage-induced epigenetics changes are fully restored after DNA repair and decipher the interplay between genetic and epigenetic restoration at different chromatin contexts. We also aim to establish the importance of genomic and epigenomic maintenance in cell identity and fate. We will determine the long-term consequences of genetic and epigenetic scars in stem cells fitness and their potential to differentiate. For visualization and mapping of breaks and epigenetic changes high end microscopy and NGS approaches will be used. Expertise in any of the above will be positively considered but not absolutely required.
Required qualifications for this position:
- First author publication(s) in a reputable journal.
- Highly motivated to develop new cutting end approaches.
- Commitment to work in a highly competitive field.
- Ability to independently drive a research project and analyse data.
- Fluent in written /spoken English and writing scientific reports/papers.
Potential candidates are strongly encouraged to contact Prof. Evi Soutoglou before applying. E-mail: E.Soutoglou@sussex.ac.uk;
Applications to posts from candidates who wish to work part-time or as job-sharers are welcome.
The University offers various schemes to provide real benefits to parents, these can be found at Family Friendly Policies
The School of Life Sciences is committed to increasing the diversity of its staff and providing an inclusive working environment. The School currently holds an Athena SWAN Silver Award, has developed a Race Equity Action Plan and hosts an active Equality, Diversity and Inclusion working group.
Applications are particularly welcomed from Black and minority ethnic candidates, and women, trans and non-binary candidates, who are under-represented in the School of Life Sciences.
The University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds.
You can find out more about our values and our EDI Strategy, Inclusive Sussex, on our webpages.
Download Job Description and Person Specification 21060 [PDF 147.88KB]
The University requires that work undertaken for the University is performed from the UK.
Visa Sponsorship Queries:
"This role has been assigned an eligible SOC code and meets the salary requirements for Skilled Worker Sponsorship if full time. Please consult our Skilled Worker Visa information page for further information about Visa Sponsorship."
“Please note that this position may be subject to ATAS clearance if you require visa sponsorship.”
How to apply
Download our academic application form [DOC 199.50KB] and Personal Details and Equal Opportunities Form [DOCX 65.11KB] and fill in all sections.
Email your completed application, and personal details and equal opportunities form, to jobapps@sussex.ac.uk
Applications should be accompanied by a full CV, a statement of research interests and aspirations (not more than 4 pages), and the names of three academic referees. [Optional]
You should attach your application form and all documents to the email in PDF format (we are unable to accept applications as google.docs or .pages) and use the format job reference number / job title / your name in the subject line.
You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.