Facilities
Explore the research facilities within the GDSC.
World-class microscopy, tissue bank and screening
Below are the cutting-edge facilities available within our Centre.
Facilities available
- Wolfson Centre for Biological Imaging
The Wolfson Centre for Biological Imaging supports scientists and researchers in GDSC to do light microscopy experiments. This facility has two confocal microscopes, two super-resolution microscopes, one multiphoton microscope, seven wide-field fluorescence microscopes and three high-throughput microscopes.
There are also five workstations running Huygens, Imaris, ScanR, Zen and a number of open source software packages, supporting deconvolution, image analysis and image quantification. The facility provides user training, troubleshooting, experimental consultation and research collaboration.
For further information contact Dr Yan Gu, manager of the Wolfson Centre for Biological Imaging.
- High-content microscopy screens of siRNA libraries
The ScanR high-content microscopy system (Olympus) allows automated data acquisition from 96-well plates or coverslips. The ScanR microscope is used in combination with Dharmacon OnTarget Plus siRNA libraries in screening experiments. siRNA libraries targeting genes in the DNA damage response and epigenetic modifications are available.
- Research Tissue Bank (RTB)
The RTB facilitates research both within the GDSC and with external collaborating institutes, but serves as an international resource to facilitate basic and translational research into the aetiology, diagnosis and prognosis of genomic instability disorders, in compliance with the laws, regulations and standards that apply to research banks.
We have samples from more than 2000 donors collected in collaboration with clinicians both in the UK and internationally. Researchers seeking access to our samples must contact the Tissue Bank Manager in the first instance. All applications are assessed by our RTB Committee and released on approval.
Our tissue culture facility comprises of a small team of dedicated specialised technicians who provide a unique service supporting the research groups within the Centre.
For further information contact Dr Lisa Woodbine, Research Tissue Bank manager (l.woodbine@sussex.ac.uk).
Contact
Genome Damage and Stability Centre
Science Park Road
University of Sussex
Falmer, Brighton
East Sussex BN1 9RQ
+44 (0)1273 678123