Publications

Article

Olaitan, S, Wagstaff, M, Sevim, O, Akieme, R, Toska, V, Humphreys, C, Shah‐Goodwin, L, Bell, J, Chevassut, T and Morgan, R G (2022) [Letter to the Editor] Assessment of mononuclear cell populations derived from human umbilical cord blood. European Journal of Haematology. ISSN 0902-4441

Parker, Christopher, Chambers, Adam C, Flanagan, Dustin J, Ho, Jasmine Wing Yu, Collard, Tracey J, Ngo, Greg, Baird, Duncan M, Timms, Penny, Morgan, Rhys G, Sansom, Owen J and Williams, Ann C (2022) BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination. DNA Repair, 115. a103331 1-11. ISSN 1568-7864

Wongwiwat, Wiyada, Fournier, Benjamin, Bassano, Irene, Bayoumy, Amr, Elgueta Karstegl, Claudio, Styles, Christine, Bridges, Ray, Lenoir, Christelle, BoutBoul, David, Moshous, Despina, Neven, Bénédicte, Kanda, Teru, Morgan, Rhys G, White, Robert E, Latour, Sylvain and Farrell, Paul J (2022) Epstein-Barr Virus genome deletions in Epstein-Barr Virus-positive T/NK cell lymphoproliferative diseases. Journal of Virology. a0039422 1-15. ISSN 0022-538X

Wagstaff, Megan, Tsaponina, Olga, Caalim, Gilian, Greenfield, Hayley, Milton-Harris, Leanne, Mancini, Erika J, Blair, Allison, Heesom, Kate J, Tonks, Alex, Darley, Richard L, Roberts, Stefan G and Morgan, Rhys G (2022) Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia. Haematologica. ISSN 0390-6078

Wagstaff, Megan, Coke, Brandon, Hodgkiss, Georgia R and Morgan, Rhys G (2022) Targeting β-catenin in acute myeloid leukaemia: past, present, and future perspectives. Bioscience Reports. ISSN 0144-8463

Menendez-Gonzalez, Juan Bautista, Sinnadurai, Samantha, Gibbs, Alex, Thomas, Leigh-anne, Konstantinou, Maria, Garcia-Valverde, Alfonso, Boyer, Magali, Wang, Zhengke, Boyd, Ashleigh S, Blair, Allison, Morgan, Rhys G and Rodrigues, Neil P (2019) Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports, 9 (1). a12212. ISSN 2045-2322

Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex and Darley, Richard L (2019) LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells. Haematologica, 104 (7). pp. 1365-1377. ISSN 1592-8721

Wadley, Alex J, Morgan, Rhys G, Darley, Richard L, Hole, Paul S and Coles, Steven J (2019) Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations. Methods in Molecular Biology. pp. 53-70. ISSN 1064-3745

Wadley, Alex J, Morgan, Rhys, Heesom, Kate J, Hole, Paul S and Coles, Steven J (2018) Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: an optimised protocol for digital flow cytometers. MethodsX, 5. pp. 1473-1483. ISSN 2215-0161

Wadley, Alex J, Holliday, Adrian, Morgan, Rhys G, Heesom, Kate J, Aldred, Sarah, Peters, Derek M, Bueno, Allain A and Coles, Steven J (2018) Preliminary evidence of reductive stress in human cytotoxic T-cells following exercise. Journal of Applied Physiology, 125 (2). pp. 586-595. ISSN 8750-7587

Morgan, R G, Mortensson, E and Williams, A C (2018) Targeting LGR5 in colorectal cancer: therapeutic gold or too plastic? British Journal of Cancer, 118. pp. 1410-1418. ISSN 0007-0920

Morgan, R G, Chambers, A C, Legge, D N, Coles, S J, Greenhough, A and Williams, A C (2018) Optimized delivery of siRNA into 3D tumor spheroid cultures in situ. Scientific Reports, 8 (7592). pp. 1-10. ISSN 2045-2322

Morgan, R G, Mortensson, E, Legge, D N, Gupta, B, Collard, T J, Greenhough, A and Williams, A C (2018) LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity. British Journal of Cancer, 118 (4). pp. 558-565. ISSN 1532-1827

Vieira, Gabriella Cunha, Chockalingam, S, Melegh, Zsombor, Greenhough, Alexander, Malik, Sally, Szemes, Marianna, Park, Ji Hyun, Kaidi, Abderrahmane, Zhou, Li, Catchpoole, Daniel, Morgan, Rhys, Bates, David O, Gabb, Peter J and Malik, Karim (2017) Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget, 8 (19). p. 32381. ISSN 1949-2553

Vieira, Gabriella Cunha, Chockalingam, S, Melegh, Zsombor, Greenhough, Alexander, Malik, Sally, Szemes, Marianna, Park, Ji Hyun, Kaidi, Abderrahmane, Zhou, Li, Catchpoole, Daniel, Morgan, Rhys G, Bates, David O, Gabb, Peter David and Malik, Karim (2015) LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget, 6 (37). pp. 40053-40067. ISSN 1949-2553

Morgan, R G, Molnár, E, Jones, R F, Collard, T J, Lane, J D, Greenhough, A, Paraskeva, C and Williams, A C (2015) Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells. British Journal of Cancer, 112 (4). pp. 714-719. ISSN 1532-1827

Morgan, Rhys G, Ridsdale, Jenna, Tonks, Alex and Darley, Richard L (2014) Factors affecting the nuclear localization of β-catenin in normal and malignant tissue. Journal of Cellular Biochemistry, 115 (8). pp. 1351-1361. ISSN 0730-2312

Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert K, Morgan, Rhys G, Tonks, Alex, Burnett, Alan K and Darley, Richard L (2014) The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica, 99 (5). pp. 858-864. ISSN 1592-8721

Morgan, R G, Liddiard, K, Pearn, L, Pumford, S L, Burnett, A K, Darley, R L and Tonks, A (2013) γ-Catenin is expressed throughout normal human hematopoietic development and is required for normal PU.1-dependent monocyte differentiation. Leukemia, 27 (10). pp. 2096-2100. ISSN 1476-5551

Morgan, R G, Pearn, L, Liddiard, K, Pumford, S L, Burnett, A K, Tonks, A and Darley, R L (2013) γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia, 27 (2). pp. 336-43. ISSN 1476-5551