GiVE 3 Trial: Now recruiting

What is the study about?  
The National Institute for Health & Care Excellence (NICE) recommends Cognitive Behavioural Therapy (CBT) for the treatment of psychosis, but only a minority of people with psychosis have the chance to receive CBT. CBT is not available to most people with psychosis because it can be quite long and needs to be delivered by highly trained therapists. 

The purpose of this study is to find out if a shorter version of CBT, delivered by briefly trained therapists, can be helpful for people who hear distressing voices. We will evaluate this form of CBT by comparing it to a control group who will receive no additional interventions.

Timelines
The study opened on 30 April 2022 and will conclude on 30 October 2024. The recruitment of participants is planned for the 12-month period from October 2022 to September 2023

Who is running the study?
We are running this study in collaboration with the Cumbria, Northumberland, Tyne & Wear NHS Foundation Trust, Pennine Care Foundation Trust, the Universities of Sussex, Manchester and Surrey, and the National Institute for Health & Care Research.

Why is the study being run?
The findings of this study will provide helpful information about ways of increasing access to CBT for people who experience distressing voice hearing.

Why should you take part?
The information we find out from this research will help provide helpful information about whether CBT delivered by briefly trained therapists is helpful for people who hear distressing voices. This will help mental health services to make decisions about what therapies should be provided for people who hear voices.

What will taking part involve?
Eligible participants will be asked to complete an assessment with a research assistant before being randomly allocated to one of the two groups within the study; one group will receive the shorter version of CBT delivered by briefly trained therapists in addition to their usual care and another group will receive only their usual care. 

A further two assessments will be completed: 16 weeks after the allocation and 28 weeks after the allocation. 

Participants will be paid £20 for each assessment they complete. The cost of travelling to the assessments can be repaid. 

Who can take part?
People can take part if they have a diagnosis of psychosis and are currently distressed by hearing voices. In total, 130 people will take part in the study; 65 will receive the shorter version of CBT delivered by briefly trained therapists in addition to their usual care and 65 will be in a control group who will continue to receive their usual care.

Contact details
Email: Give3@spft.nhs.uk  

Download an information flyer here