Biochemistry and Biomedicine


We study genes and proteins which cause diseases, allowing us to explore approaches to maintaining human and animal health.

We have an established reputation for collaborative and interdisciplinary approaches to research and teaching

  • Our Biological Sciences research (as submitted to UoA 05 – Biological Sciences) was assessed overall to be 35% ‘world leading’ (4*) and 59% ‘internationally excellent’ (3*). In particular, over 90% of research outputs, 100% of impact cases and 100% of our research environment were assessed as 3* or 4* in the most recent Research Excellence Framework (REF 2021).
Our areas of interest

The overarching theme of our research and teaching can be summarised by the exploration of disease-causing genes and proteins and approaches to maintaining human and animal health.

Our research ranges from cell-based genome and proteome-wide analyses to experiments at single molecule resolution using cell biology, structural biology and bioinformatics. There is a strong focus on human health and food security but deliberate encouragement to complement this with the investigation of basic mechanisms within other organisms.

Who we work with

We have many important internal collaborations with the Sussex Drug Discovery Centre, Genome Damage and Stability Centre, Sussex Neuroscience, The Gene Expression Research Group, and Brighton and Sussex Medical School.

We also work closely with external research partners.

Our funders
  • The Medical Research Council
  • The Biotechnology, Bioscience Research Council
  • Cancer Research UK
  • The Wellcome Trust
  • Bloodwise
  • Action Against Cancer
  • Wysta Laboratories
  • The Kay Kendall Leukeamia Research Fund
  • Agform Ltd
  • The European Union
  • Evotech UK
  • The Royal Society
  • Innovate UK
Our facilities
Our courses

Contact Us

Dr Leandro Castellano

Head of Department


T 01273 678382