The Sussex Psychosis Research interest Group (SPRiG) incorporates clinical and academic researchers within the University of Sussex, Brighton and Sussex Medical School and Sussex Partnership NHS Foundation Trust. The SPRiG group is part of the Clinical and Developmental research group at the University of Sussex.
Current research includes the contribution of genetics, neuroimaging, psychological processes, health and social contexts to psychosis and well-being outcomes; the development of new psychological therapies, including third wave CBT and computer-based therapies; understanding and addressing childrens’ and adolescents’ attitudes to psychosis, to promote positive non-stigmatising schema; and earlier engagement in help seeking.
We host SPRiG seminars throughout the year at University of Sussex or Sussex Education Centre. Visit our events pages for more information or follow us on Twitter for updates on psychosis new items, research projects and psychosis events. @SPRiGSussex
Our next seminar is: Wednesday 27th March 4.00-5.00pm
Speaker: Prof James Stone: Professor of Psychiatry, Brighton and Sussex Medical School
“Beyond dopamine – where are we now with the glutamate theory of psychosis?”
Changes in brain glutamate and interactions with the dopamine system have long been suspected to underlie the development of schizophrenia, although evidence has not always been consistent. In this talk, I will review the current evidence for the glutamate hypothesis of schizophrenia and the MAM model of psychosis, including findings from preclinical and clinical studies. I will consider whether glutamatergic neurotransmission should still be considered as a potential target for treatment, reviewing the findings from clinical trials of novel glutamatergic agents in schizophrenia.
Join Zoom link:
https://universityofsussex.zoom.us/j/95344009931