The Laboratory of Neuronal Ensembles Involved in Learned Behaviours

The Laboratory of Neuronal Ensembles Involved in Learned Behaviours (PI: Eisuke Koya) seeks to understand how learned associations about rewarding substanced (e.g. food, drugs) and their associated environmental stimuli are encoded in a minority of sparsely distributed, behaviourally activated neurons called 'neuronal ensembles'. Our goals are to identify the brain areas where these neuronal ensembles reside, and to further characterise the alterations in intrinsic membrane properties and synaptic physiology on these activated neurons that allow these learned associations to be established and maintained. We use a variety of transgenic  approaches, in which behaviourally activated neurons that express the activity-regulated protein 'Fos' can be selectively silenced and electrophysiologically characterised.

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Principal Investigator

Dr. Eisuke Koya
CRPC 5.14
School of Psychology
University of Sussex
Falmer, BN1 9QG
United Kingdom

Eisuke Koya's profile