Dr Julian Thorpe
Carroll, Jean, Page, Tristan K W, Chiang, Shih-Chieh, Kalmar, Bernadett, Bode, David, Greensmith, Linda, Mckinnon, Peter J, Thorpe, Julian R, Hafezparast, Majid and El-Khamisy, Sherif F (2015) Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing. Human Molecular Genetics, 24 (3). pp. 828-40. ISSN 1460-2083
Sanders , David W, Kaufman , Sarah K, DeVos, Sarah L, Sharma , Apurwa M, Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J, Foley, Alex C, Thorpe, Julian R, Serpell, Louise C, Miller, Timothy M, Grinberg, Lea T, Seeley , William W and Diamond, Marc I (2014) Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron. ISSN 0896-6273
Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William, Morris, Kyle L, Sada, Alaa, Thorpe, Julian R and Serpell, Louise C (2013) A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease. Acta Neuropathologica Communications, 1 (83). pp. 1-17. ISSN 2051-5960
Whitby, Raymond L D, Korobeinyk, Alina V, Gun'ko, Vladimir M, Wright, Daniel B, Dichello, Gennaro, Smith , Lauren C, Fukuda, Takahiro, Maekawa, Toru, Thorpe, Julian R and Mikhalovsky, Sergey V (2013) Single-layer graphenes functionalized with polyurea: architectural control and biomolecule reactivity. Journal of Physical Chemistry C, 117 (22). pp. 11829-11836. ISSN 1932-7447
Soura, Violetta, Stewart-Parker, Maris, Williams, Thomas L, Ratnayaka, Arjuna, Atherton, Joe, Gorringe, Kirsti, Tuffin, Jack, Darwent, Elisabeth, Rambaran, Roma, Klein, William, Lacor, Pascale, Staras, Kevin, Thorpe, Julian and Serpell, Louise (2012) Visualisation of co-localisation in Ab42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochemical Journal, 441 (2). pp. 579-590. ISSN 0264-6021
Marra, Vincenzo, Burden, Jemima J, Thorpe, Julian R, Smith, Ikuko T, Smith, Spencer L, Häusser, Michael, Branco, Tiago and Staras, Kevin (2012) A preferentially segregated recycling vesicle pool of limited size supports neurotransmission in native central synapses. Neuron, 76 (3). pp. 579-589. ISSN 0896-6273
Page, Tristan, Gitcho, Michael A, Mosaheb, Sabrina, Carter, Deborah, Chakraverty, Sumi, Perry, Robert H, Bigio, Eileen H, Gearing, Marla, Ferrer, Isidre, Goate, Alison M, Cairns, Nigel J and Thorpe, Julian R (2011) FUS immunogold labelling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience, 45 (3). pp. 409-421. ISSN 0895-8696
Acevedo-Arozena, Abraham, Kalmar, Bernadett, Essa, Shafa, Ricketts, Thomas, Joyce, Peter, Kent, Rosie, Rowe, Claire, Parker, Andy, Gray, Anna, Hafezparast, Majid, Thorpe, Julian R, Greensmith, Linda and Fisher, Elizabeth M C (2011) A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. Disease Models and Mechanisms, 4 (5). pp. 686-700. ISSN 1754-8403
Paine, Simon, Bedford, Lynn, Thorpe, Julian R, Mayer, R John, Cavey, James R, Bajaj, Nin, Sheppard, Paul W, Lowe, James and Layfield, Robert (2009) Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration. Neuroscience Letters, 460. pp. 205-208.
Thorpe, Julian R, Tang, Helen, Atherton, Joe and Cairns, Nigel J (2008) Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy. Journal of Neural Transmission, 115. pp. 1661-1671.
Hashemzadeh-Bonehi, Lida, Phillips, Roger Guy, Cairns, Nigel John, Mosaheb, Sabrina and Thorpe, Julian Robert (2006) Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration. Experimental Neurology, 199 (2). pp. 328-338. ISSN 0014-4886
Morris, Christopher, Thorpe, Julian, Ambrosio, Luigi and Santin, Matteo (2006) The soybean isoflavone genistein induces differentiation of MG63 human osteosarcoma osteoblasts. Journal of Nutrition, 136 (5). pp. 1166-1170. ISSN 0022-3166
Mosaheb, Sabrina, Thorpe, Julian R, Hashemzadeh-Bonehi, Lida, Bigio, Eileen H, Gearing, Marla and Cairns, Nigel J (2005) Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease (NIFID). Acta Neuropathologica, 110. pp. 360-368. ISSN 0001-6322
Thorpe, Julian R, Mosaheb, Sabrina, Hashemzadeh-Bonehi, Lida, Cairns, Nigel J, Kay, John E, Morley, Simon J and Rulten, Stuart L (2004) Shortfalls in the Peptidyl-Prolyl Cis-Trans Isomerase Protein Pin 1 in Neurons are Associated with Frontotemporal Dementias. Neurobiology of Disease, 17 (2). pp. 237-249. ISSN 0969-9961
Cairns, N J, Grossman, M, Arnold, SE, Burn, D J, Jaros, E, Perry, RH, Duyckaerts, C, Stankoff, B, Pillon, B, Skullerud, K, Cruz-Sanchez, F F, Bigio, E H, Mackenzie, I R, Gearing, M, Juncos, J L, Glass, J D, Yokoo, H, Nakazato, Y, Mosaheb, S, Thorpe, J R, Uryu, K, Lee, V M and Trojanowski, J Q (2004) Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease (NIFID). Neurology, 63 (8). pp. 1376-1384. ISSN 1526-632X
Hashemzadeh-Bonehi, Lida, Curtis, Penelope S, Morley, Simon J, Thorpe, Julian R and Pain, Virginia M (2003) Overproduction of a conserved domain of fission yeast and mammalian translation initiation factor eIF4G causes aberrant cell morphology and results in disruption of the localization of F-actin and the organization of microtubules. Genes to Cells, 8 (2). pp. 163-178. ISSN 1356-9597
Jayeola, A A, Thorpe, J R and Adenegan, T A (2001) Macromorphological and Micromorphological Studies of the West African Rhizophora Linn. Feddes Repertorium, 112 (5-6). pp. 337-344. ISSN 0014-8962
Thorpe, Julian R, Morley, Simon J and Rulten, Stuart L (2001) Utilizing the Peptidyl-Prolyl Cis-Trans Isomerase Pin 1 as a Probe of its Phosphorylated Target Proteins: Examples of Binding to Nuclear Proteins in a Human Kidney Cell Line and to Tau in Alzheimer's Diseased Brain. Journal of Histochemistry and Cytochemistry, 49 (1). pp. 97-108. ISSN 0022-1554
Pandya, Maya, Spooner, Gillian M, Sunde, Margaret, Thorpe, Julian R, Rodger, Alison and Woolfson, Derek N (2000) Sticky-end assembly of a designed peptide fibre provides insight into protein fibrillogenesis. Biochemistry, 39. pp. 8728-8734. ISSN 0006-2960
Jayeola, A A and Thorpe, J R (2000) A Scanning Electron Microscope Study of the Adaxial Leaf Surface of the Genus Calyptrochilum KRAENZL. (Orchidaceae) in West Africa. Feddes Repertorium, 111 (5-6). pp. 315-320.
Thorpe, Julian R, Rulten, Stuart L and Kay, John E (1999) The binding of a putative and a known chaperone protein revealed by immunogold labelling transmission electron microscopy: A suggested use of chaperones as probes for the distribution of their target proteins. Journal of Histochemistry and Cytochemistry, 47. pp. 1633-1640.
Richardson, G P, Forge, A, Kros, C J, Marcotti, W, Becker, D, Williams, D S, Thorpe, J, Fleming, J, Brown, S D and Steel, K P (1999) A missense mutation in myosin VIIA prevents aminoglycoside accumulation in cochlear hair cells. Annals of the New York Academy of Sciences, 884. pp. 110-124.
Rulten, Stuart L, Thorpe, Julian R and Kay, John Edward (1999) Identification of eukaryotic parvulin homologues: a new subfamily of peptidylprolyl cis-trans isomerases. Biochemical and Biophysical Research Communications, 259 (3). pp. 557-562. ISSN 0006-291X
Thorpe, Julian (1999) The application of LR gold resin for immunogold labelling. In: Hajibagheri, MA (ed.) Electron Microscopy Methods and Protocols. Humana Press, Totowa, New Jersey, pp. 99-110. ISBN 0896036405
Matteo, M A, Loweth, A C, Thomas, S, Mabley, J G, Morgan, N G, Thorpe, J R and Green, I C (1997) Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms. Apoptosis, 2. pp. 164-177. ISSN 1360-8185
Thorpe, Julian (1996) When is a spine not a spine? A new look at an old problem in the taxonomy of the Baetidae (Ephemeroptera). The Entomologist, 115. pp. 86-90.
Thorpe, Julian (1993) Dehydration methods. In: Robards, AW and Wilson, AJ (eds.) Procedures in Electron Microscopy. Wiley. ISBN 9780471928539
Thorpe, Julian (1992) Development and distribution of mitochondrial enzymes in leaves. In: Lambers, H and van der Plas, L (eds.) Molecular, biochemical and physiological aspects of plant respiration. Balogh Scientific Books, pp. 177-193. ISBN 9789051030792
Thorpe, Julian (1992) A novel methodology for double protein A-gold immunolabelling utilizing the monovalent fragment of protein A. Journal of Histochemistry and Cytochemistry, 40 (3). pp. 435-441. ISSN 0022-1554
Thorpe, Julian (1991) Eggs of British meniscus midges (Diptera: Dixidae) observed by scanning electron microscopy. Freshwater Forum, 1 (3). pp. 215-224. ISSN 0961-4664
Thorpe, J R and Wallis, M (1991) Immunocytochemical and morphometric investigations of mammotrophs, somatotrophs and somatomammotrophs in sheep pituitary cell cultures. Journal of Endocrinology, 129. pp. 417-422.
Khawaja, X Z, Green, I C, Thorpe, Julian and Bailey , C J (1990) Iincreased sensitivity to insulin-releasing and glucoregulatory effects of dynorphin-A1-13 and U-50488H in OB/OB versus lean mice. Diabetes, 39. pp. 1289-1297.
Thorpe, J R, Ray, K P and Wallis, M (1990) Occurrence of rare somatomammotrophs in ovine anterior pituitary tissue studied by immunogold labelling and electron microscopy. Journal of Endocrinology, 124. pp. 67-73.
Khawaja, X Z, Green, I C, Thorpe, J R and Titheradge, M A (1990) The occurrence and receptor specificity of endogenous opioid peptides within the pancreas and liver of the rat - comparison with brain. Biochemical Journal, 267. pp. 233-240.
Tobin, Alyson K, Thorpe, Julian R, Hylton, Christopher M and Rawsthorne, Stephen (1989) Spatial and temporal influences on the cell-specific localisation of glycine decarboxylase in leaves of wheat (Triticum aestivum) and pea (Pisum sativum). Plant Physiology, 91. pp. 1219-1225. ISSN 0032-0889
Harvey, Diana M R and Thorpe, J R (1986) Some observations on the effects of salinity on ion distributions and cell ultrastructure in wheat leaf mesophyll cells. Journal of Experimental Botany, 37. pp. 1-7.
Thorpe, J R and Hall, J L (1984) Chronology and elicitation of changes in peroxidase and phenylalanine ammonia lyase activities in wounded wheat leaves in response to innoculation by Botrytis cinerea. Physiological Plant Pathology, 25. pp. 363-379.
Hall, J L, Kinney, A J, Dymott, A, Thorpe, J R and Brummell, D A (1982) Localisation and properties of ATPase activity in pea stems and wheat coleoptiles. Histochemical Journal, 14. pp. 323-331.
Thorpe, Julian R and Harvey, Diana M R (1979) Optimisation and investigation of the use of 2,2-dimethoxypropane as a dehydration agent for plant tissues in transmission electron microscopy. Journal of Ultrastructure Research, 68. pp. 186-194.
Pope, D G, Thorpe, J R, Al-Azzawi, M J and Hall, J L (1979) The effect of cytochalasin B on the rate of growth and ultrastructure of wheat coleoptiles and maize roots. Planta, 144. pp. 373-383. ISSN 0032-0935
Baker, D A, Hall, J L and Thorpe, J R (1978) A study of the extrafloral nectaries of Ricinus communis. New Phytologist, 81 (1). pp. 129-137.