The Staras Laboratory
Synaptic signalling mechanisms in central neurons
Chemical synapses are the key sites for transmission of information around neuronal networks in the brain. The main focus of our research is to explore the functional and structural properties of presynaptic terminals in CNS neurons. The findings have major implications for current models of neuron-neuron communication and for understanding forms of plasticity underlying learning and memory. Additionally, current work is also focussed on elucidating Alzheimer’s-related defects in synaptic function, providing novel substrates for therapeutic approaches. Other research interests interface with informatics; work with a European consortium is characterizing novel mechanisms of neuronal plasticity to inform new AI and robotics architectures.
Research funded by:
