Selected publications (For a full list, use the link to pubmed on the right)

Alatwi, HE, and JA Downs (2015) Removal of H2A.Z by INO80 promotes homologous recombination.  EMBO Reports, doi 10.15252/embr.201540330.

Kakarougkas A, Ismail A, Chambers AL, Riballo E, Herbert AD, Kunzel J, Lobrich M, Jeggo PA, and JA Downs (2014) Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.  Molecular Cell, 55(5):723-732.

Lopez-Perrote A, Alatwi HE, Torreira E, Ismail A, Avora S, Downs JA and O Llorca (2014) Structure of Yin Yang 1 Oligomers that cooperate with RuvBL1-RuvBL2 ATPases.  Journal of Biological Chemistry, 289: 22614-22629.

Brownlee PM, Chambers AL, Cloney R, Bianchi A and JA Downs (2014) BAF180 promotes cohesion and prevents genome instability and aneuploidy.  Cell Reports, 6(6): 973-981.

Chambers AL, Pearl LH, Oliver AW and JA Downs (2013) The BAH domain of Rsc2 is a histone H3 binding domain.  Nucl Acids Res 41(19): 9168-9182.

Chambers AL, Ormerod G, Durley SC, Sing T, Brown GW, Kent NA and JA Downs (2012) The INO80 chromatin remodelling complex prevents polyploidy and maintains normal chromatin structure at centromeres.  Genes and Development 26(23): 2590-2603.

Niimi A, Chambers AL, Downs JA and AR Lehmann (2012) A role for chromatin remodellers in replication of damaged DNA.  Nucl Acids Res. 40(15): 7393-7403.

Chambers AL, Brownlee PM, Durley SC, Beacham T, Kent NA and JA Downs (2012) The two isoforms of the RSC chromatin remodelling complex play distinct roles in DNA damage responses.  PLoS One 7(2): e32016.

Publications with abstracts and links