Role

Professor of Biochemistry

Bartlett, EJ, Brissett, NC and Doherty, Aidan (2013) Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates. Proceedings of the National Academy of Sciences of the United States of America, 110 (22). E1984-E1991. ISSN 1091-6490

Brissett, Nigel C, Martin, Maria J, Pitcher, Robert S, Bianchi, Julie, Juarez, Raquel, Green, Andrew J, Fox, Gavin C, Blanco, Luis and Doherty, Aidan J (2011) Structure of a preternary complex involving a prokaryotic NHEJ DNA polymerase. Molecular Cell, 41 (2). pp. 221-231. ISSN 1097-2765

Malyarchuk, Svitlana, Wright, Douglas, Castore, Reneau, Klepper, Emily, Weiss, Bernard, Doherty, Aidan J and Harrison, Lynn (2007) Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in recA-independent DNA end-joining at regions of microhomology. DNA repair, 6 (10). pp. 1413-1424. ISSN 1568-7864

Pitcher, Robert S, Tonkin, Louise M, Daley, James M, Palmbos, Phillip L, Green, Andrew, Velting, Tricia L, Brzostek, Anna, Korycka-Machala, Malgorzata, Cresawn, Steve, Dziadek, Jaroslaw, Hatfull, Graham F, Wilson, Thomas E and Doherty, Aidan J (2006) Mycobacteriophage exploit NHEJ to facilitate genome circularization. Molecular Cell, 23 (5). pp. 743-748. ISSN 1097-2765

Chavali, Gayatri B, Ekblad, Caroline M S, Basu, Balaka P, Brissett, Nigel C, Veprintsev, Dmitry, Hughes-Davies, Luke, Kouzarides, Tony, Itzhaki, Laura S and Doherty, Aidan J (2005) Crystal structure of the ENT domain of human EMSY. Journal of Molecular Biology, 350 (5). pp. 964-973. ISSN 0022-2836

Della, Marina, Palmbos, Phillip L, Tseng, Hui-Min, Tonkin, Louise M, Daley, James M, Topper, Leana M, Pitcher, Robert S, Tomkinson, Alan E, Wilson, Thomas E and Doherty, Aidan J (2004) Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science, 306 (5696). pp. 683-685. ISSN 0036-8075

Iwabuchi, Kuniyoshi, Basu, Balaka Piku, Kysela, Boris, Kurihara, Takayuki, Shibata, Masao, Guan, Deyu, Cao, Yongheng, Hamada, Tomio, Imamura, Kouji, Jeggo, Penny A, Date, Takayasu and Doherty, Aidan J (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

Weller, Geoffery R, Kysela, Boris, Roy, Rajat, Tonkin, Louise M, Scanlan, Elizabeth, Della, Marina, Devine, Susanne Krogh, Day, Jonathan P, Wilkinson, Adam, d'Adda di Fagagna, Fabrizio, Devine, Kevin M, Bowater, Richard P, Jeggo, Penny A, Jackson, Stephen P and Doherty, Aidan J (2002) Identification of a DNA nonhomologous end-joining complex in bacteria. Science, 297. pp. 1686-1689. ISSN 0036-8075