Dr Lihong Zhou
| Post: | Research Laboratory Manager (Genome Damage and Stability) |
| Location: | Genome Centre G2.07 |
| Email: | Lihong.Zhou@sussex.ac.uk |
Telephone numbers | |
| Internal: | 7503 or 4801 |
| UK: | (01273) 877503 or (01273) 606755 ext. 4801 |
| International: | +44 1273 877503 or +44 1273 606755 ext. 4801 |
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Biography
2008 – 2011 Research Fellow, Wohl Virion Centre, Division of Immunity & Infection, University College London
2006 – 2008 Research Fellow, Department of Biochemistry & Molecular Biology, University College London
2005 – 2006 Postdoctoral Research Assistant, Institute of Structure Biology, Edinburgh University
2002 – 2004 Research Fellow, Genome Centre, Sussex University
2001 – 2002 Postdoctoral Research Assistant, The Biological NMR Centre, Leicester University
Selected Publication
1. Morgan RML , Herna´ndez-Ram´rez LC, Trivellin G, Zhou L, Roe SM, Korbonits M, Prodromou C Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition PLos One 2012 Dec. 7(12): e53339
2. Zhou L, Sokolskaja E, Jolly C, James W, Cowley SA, Fassati A. Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration. PLoS Pathog. 2011 Aug; 7(8): e1002194. Epub 2011 Aug.25.
3. Vozzolo L, Loh B, Gane PJ, Tribak M, Zhou L, Anderson I, Nyakatura E, Jenner RG, Selwood D, Fassati A. Gyrase B inhibitor impairs HIV-1 replication by targeting Hsp90 and the capsid protein. J Biol Chem. 2010 Dec 10; 285(50): 39314-28. Epub 2010 Oct 11
4. Zhou L, Li J, George R, Ruchaud S, Zhou HG, Ladbury JE, Earnshaw WC, Yuan X. Effects of full-length borealin on the composition and protein-protein interaction activity of a binary chromosomal passenger complex. Biochemistry. 2009 Feb 17; 48(6):1156-61.
5. Zhou L, Poh RP, Marks TS, Chowdhry BZ, Smith AR. Structure and denaturation of 4-chlorobenzoyl coenzyme A dehalogenase from Arthrobacter sp. strain TM-1. Biodegradation. 2008 Feb;19(1):65-75. Epub 2007 Apr 13.
6. Zhou L, Watts FZ. Nep1, a Schizosaccharomyces pombe deneddylating enzyme. Biochem J. 2005 Jul 15; 389(Pt 2):307-14.
7. Zhou L, Marks TS, Poh RP, Smith RJ, Chowdhry BZ, Smith AR. The purification and characterisation of 4-chlorobenzoate:CoA ligase and 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain TM-1. Biodegradation. 2004 Apr; 15(2):97-109.
8. Petkovic H, Thamchaipenet A, Zhou L, Hranueli D, Raspor P, Waterman PG & Hunter IS (1999) Disruption of an aromatase/cyclase from the oxytetracycline gene cluster of Streptomyces rimosus results in production of novel polyketides with shorter chain lengths. Journal of Biological Chemistry 274, 32829-32834.