Publications

Selected publications

 

Article

Watts, Felicity Z (2016) Repair of DNA double-strand breaks in heterochromatin. Biomolecules, 6 (4). p. 47. ISSN 2218-273X

Jongjitwimol, Jirapas, Baldock, Robert A, Morley, Simon J and Watts, Felicity Z (2016) Sumoylation of eIF4A2 affects stress granule formation. Journal of Cell Science, 129 (12). pp. 2407-2415. ISSN 0021-9533

Densham, Ruth M, Garvin, Alexander J, Stone, Helen R, Strachan, Joanna, Baldock, Robert A, Daza-Martin, Manuel, Fletcher, Alice, Blair-Reed, Sarah, Beesley, James, Johal, Balraj, Pearl, Laurence H, Neely, Robert, Keep, Nicholas H, Watts, Felicity Z and Morris, Joanna R (2016) Human BRCA1-BARD1 ubiquitin ligase activity counters chromatin barriers to DNA resection. Nature Structural and Molecular Biology, 23. pp. 647-655. ISSN 1545-9993

Baldock, Robert A, Day, Matthew, Wilkinson, Oliver J, Cloney, Ross, Jeggo, Penelope A, Oliver, Antony W, Watts, Felicity Z and Pearl, Laurence H (2015) ATM localization and heterochromatin repair depend on Direct Interaction of the 53BP1-BRCT2 domain with γH2AX. Cell Reports, 13 (10). pp. 2081-2089. ISSN 2211-1247

Watts, Felicity Z, Baldock, Robert, Jongjitwimol, Jirapas and Morley, Simon J (2014) Weighing up the possibilities: controlling translation by ubiquitylation and sumoylation. Translation, 2 (2). e959366-1. ISSN 2169-074X

Garg, Mansi, Gurung, Resham L, Mansoubi, Sahar, Ahmed, Jubed O, Davé, Anoushka, Watts, Felicity Z and Bianchi, Alessandro (2014) Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association. EMBO Reports. ISSN 1469-3178

Jongjitwimol, Jirapas, Feng, Min, Zhou, Lihong, Wilkinson, Oliver, Small, Lauren, Baldock, Robert, Taylor, Deborah L, Smith, Duncan, Bowler, Lucas, Morley, Simon J and Watts, Felicity (2014) The S. pombe translation initiation factor eIF4G is sumoylated and associates with the SUMO protease Ulp2. PLoS ONE, 9 (5). e94182. ISSN 1932-6203

Watts, Felicity Z (2013) Starting and stopping SUMOylation. What regulates the regulator? Chromosoma, 122 (6). pp. 451-463. ISSN 0009-5915

Watts, Felicity Z and Hoffmann, Eva (2011) SUMO meets meiosis: an encounter at the synaptonemal complex: SUMO chains and sumoylated proteins suggest that heterogeneous and complex interactions lie at the centre of the synaptonemal complex. BioEssays, 33. pp. 529-33. ISSN 0265-9247

Boyd, L K, Mercer, B, Thompson, D, Main, E and Watts, F Z (2010) Characterisation of the SUMO-like domains of Schizosaccahromyces pombe Rad60. PLoS ONE, 5 (9). e13009. ISSN 1932-6203

Boyd, Lara K, Mercer, Brenda, Thompson, Darren, Main, Ewan and Watts, Felicity W (2010) Characterisation of the SUMO-like domains of Schizosaccharomyces pombe Rad60. PLoS ONE, 5 (9). pp. 1-11. ISSN 1932-6203

Watts, Felicity Z and Brissett, Nigel C (2010) Linking up and interacting with BRCT domains. DNA Repair, 9 (2). pp. 103-8. ISSN 1568-7864

Spirek, Mario, Estreicher, Anna, Csaszar, Edina, Wells, Jennifer, McFarlane, Ramsay J, Watts, Felicity Z and Loidl, Josef (2010) Sumoylation is required for normal development of linear element and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma, 9 (11). pp. 59-72. ISSN 0009-5915

Spirek, M, Estredicher, A, Csaszar, E, Wells, J, McFarlane, Ramsay J, Watts, Felicity and Loidl, J (2010) SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma, 119 (1). pp. 59-72. ISSN 1432-0886 (Electronic)

Skilton, Andrew, Outwin, Emily, Mercer, Brenda, Ho, J C Y and Watts, Felicity (2009) SUMO chain formation is required for response to replication arrest in S. pombe. PLoS ONE, 4 (8). e6750. ISSN 1932-6203

Kilkenny, Mairi L, Doré, Andrew S, Roe, S Mark, Nestoras, Konstantinos, Ho, Jenny C Y, Watts, Felicity Z and Pearl, Laurence H (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signalling. Genes and Development, 22 (15). pp. 2034-47. ISSN 0890-9369

Kilkenney, M L, Dore, A, Roe, S M, Nestoras, K, Ho, J, Watts, F Z and Pearl, L (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes and Development, 22 (15). pp. 2034-2047. ISSN 0890-9369

Watts, Felicity, Skilton, Andrew, Ho, J C, Boyd, Lara Katrina, Trickey, M A, Gardner, Lisa and Ogi, Francois-Xavier (2007) The role of Schizosaccharomyces pombe SUMO ligases in genome stability. Biochemical Society Transactions, 35 (6). pp. 1379-1384. ISSN 0300-5127

Watts, Felicity (2007) The role of SUMO in chromosome segregation. Chromosoma, 116 (1). pp. 15-20. ISSN 1432-0886

Frampton, Jonathan, Irmisch, Anja, Green, Catherine M, Neiss, Andrea, Trickey, Michelle, Ulrich, Helle D, Furuya, Kanji, Watts, Felicity, Carr, Antony M and Lehmann, Alan R (2006) Postreplication Repair and PCNA Modification in Schizosaccharomyces pombe. Molecular Biology of the Cell, 17 (7). pp. 2976-2985. ISSN 1059-1524

Watts, Felicity (2006) Sumoylation of PCNA: Wrestling with recombination at stalled replication forks. DNA Repair, 5 (3). pp. 399-403. ISSN 1568-7864

Shin, Jin, Choi, Eun Shik, Kim, Hyun Soo, Ho, J C, Watts, Felicity Z, Park, Sang D and Jang, Yeun Kyu (2005) SUMO modification is involved in the maintenance of heterochromatin stability in fission yeast. Molecular Cell, 19 (6). pp. 817-828. ISSN 1097-2765

Sergeant, John, Taylor, Elaine, Palecek, Jan, Fousteri, Maria, Andrews, Emily, Sweeney, Sara, Shinagawa, Hideo, Watts, Felicity and Lehmann, Alan (2005) Composition and Architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) Complex. Molecular and Cellular Biology, 25 (1). pp. 172-184. ISSN 0270-7306

Andrews, Emily A, Palecek, Jan, Sergeant, John, Taylor, Elaine, Lehmann, Alan R and Watts, Felicity Z (2005) Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Molecular and Cellular Biology, 25 (1). pp. 185-196. ISSN 0270-7306

Zhou, Lihong and Watts, Felicity (2005) Nep1, a Schizosaccharomyces pombe deneddylating enzyme. Biochemical Journal, 389 (Pt 2). pp. 307-314. ISSN 0264-6021

Spink, K, Ho, J C, Tanaka, K, Watts, Felicity and Chambers, Anna (2005) The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast. Biochemical Genetics, 43 (3-4). pp. 103-17. ISSN 0006-2928

Watts, Felicity (2004) SUMO modification of proteins other than transcription factors. Seminars in Cell & Developmental Biology, 15 (2). pp. 211-220. ISSN 10849521

Ho, J C and Watts, Felicity (2003) Characterisation of SUMO conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant negative allele which severely reduces SUMO conjugation. Biochemical Journal, 21. ISSN 0264-6021

Hinks, J, Roe, Mark, Ho, J C, Watts, Felicity, Phelan, J, McAllister, M and Pearl, Laurence (2003) Expression, purification and preliminary X-ray analysis of the BRCT domain from Rhp9/Crb2. Acta Crystallographica Section D: Biological Crystallography, 59 (Pt 7). 1230-1233.. ISSN 0907-4449

Taylor, Deborah, Ho, Jenny, Oliver, Alejandro and Watts, Felicity (2002) Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease. Journal of Cell Science, 115 (6). pp. 1113-1122. ISSN 0021-9533

Ho, J C, Warr, N J, Shimizu, H and Watts, Felicity (2001) SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52. Nucleic Acids Research, 29 (20). pp. 4179-4186. ISSN 1362-4962

Watts, F.Z. and Hofmann, E.  (2011) SUMO meets meiosis: an encouner at the synaptonemal complex. Bioessays 33, 529-37

Boyd, L.K., Mercer, B., Main, E, Thompson, D. Watts, F.Z. (2010) Characterisation of the SUMO-like domains of Schizosaccahromyces pombe Rad60. PlosOne, Sep 27;5(9):e13009

Watts F.Z. and Brissett N.C. (2010) Linking up and interacting with BRCT domains. DNA Repair 9, 103-8

Spirek M., Estreicher A., Csaszar E., Wells J., McFarlane R.J., Watts F.Z. and Loidl J. (2010) Sumoylation is required for normal development of linear element and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma. 9:59-72.

Skilton A., Ho J.C., Mercer B., Outwin E. and Watts F.Z. (2009) SUMO chain formation is required for response to replication arrest in S. pombe. PlosONE 4, e6750 

 Kilkenney, M.L. Dore, A., Roe, S.M., Nestoras, K., Ho, J.C.Y., Watts, F.Z. and Pearl, L.H.  (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signalling and DNA damage repair Genes and Dev. 22, 2034-47.

Watts, F. Z., Skilton, A., Ho, J. C., Boyd, L. K., Trickey, M. A., Gardner, L., Ogi, F. X., Outwin, E. A. (2007) The role of Schizosaccharomyces pombe SUMO ligases in genome stability. Biochem. Soc. Trans. 35, 1379-84. 

Watts, F.Z. (2007) The role of SUMO in chromosome segregation. Chromosoma 116, 15-20.

Frampton, J,., Irmisch, A., Neiss, A., Trickey, M., Green, C.M., Ulrich, H.D., Furuya, K., Watts, F.Z., Carr, A.M. and Lehmann, A.R. (2006) Post-replication repair and PCNA modification in Schizosaccharomyces pombe. Mol Biol Cell 17, 2976-85.

Watts, F.Z. (2006) Sumoylation of PCNA: Wrestling with recombination at stalled replication forks. DNA Repair 5, 399-403.

Shin, J.A, Chin, E.S., Kim, H.S. Ho, J.C.Y., Watts, F.Z., Park, S.D, and Jang, Y.K (2005) SUMO modification is involved in the maintenance of heterochromatin stability in fission yeast. Mol Cell. 19, 817-28.

Spink, K, Ho, J.C.Y, Tanaka, K., Watts, F.Z. and Chambers, A. (2005) The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast. Biochem Genet. 43, 103-17.

Zhou, L. and Watts, F.Z. (2005) Nep1, an S. pombe deneddylating enzyme. Biochem J.  389, 307-14.

Andrews E.A., Palecek J., Sergeant J., Taylor E., Lehmann A.R., and Watts F.Z. (2005) Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Mol Cell Biol. 25, 185-196.

Sergeant J., Taylor E., Palecek J., Fousteri M., Andrews E.A., Sweeney S., Shinagawa H., Watts F.Z., and Lehmann A.R. (2005) Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex. Mol. Cell Biol. 25, 172-184.

Hinks J.A., Roe M., Ho J.C., Watts F.Z., Phelan J., McAllister M., and Pearl L.H. Expression, purification and preliminary X-ray analysis of the BRCT domain from Rhp9/Crb2. Acta Crystallogr D Biol Crystallogr. (2003) 59, 1230-3

Ho, J.C.Y. and Watts, F.Z. Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation. Biochem J. (2003) 372, 97-104

Taylor, D.L. Ho, J.C.Y., Oliver, A. and Watts, F.Z. Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease. J. Cell Sci. (2002) 115, 1113-1122.

Ho, J.C.Y., Warr, N.J., Shimizu, H., Watts, F.Z. SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52.  Nucl. Acids Res. (2001) 29, 4179-86.

Publications with abstracts and links

PubMed