Regulating the Transcriptome (C7132)
15 credits, Level 6
This module takes an up-to-the-minute look at the molecular mechanisms controlling RNA expression in prokaryotes and eukaryotes, focusing largely on gene transcription but also examining RNA processing events in eukaryotes.
We will examine the way in which bacteria control gene expression in response to different environmental cues through precisely coordinated transcription regulatory networks, and investigate the way in which eukaryotic transcriptional regulators control RNA polymerase recruitment and retention and modulate chromatin structure during transcriptional activation and repression.
Understanding these processes and mechanisms is fundamental for the study of health and disease, for example to aid the development of new antibiotics and decipher how gene regulatory networks are perturbed during cancer development.
30%: Coursework (Essay)
70%: Examination (Unseen examination)
Contact hours and workload
This module is approximately 150 hours of work. This breaks down into about 32 hours of contact time and about 118 hours of independent study. The University may make minor variations to the contact hours for operational reasons, including timetabling requirements.
This module is running in the academic year 2020/21. We also plan to offer it in future academic years. It may become unavailable due to staff availability, student demand or updates to our curriculum. We’ll make sure to let our applicants know of such changes to modules at the earliest opportunity.
This module is offered on the following courses: