Protein Form and Function (Level 7) (846C1)

15 credits, Level 7 (Masters)

Spring teaching

Proteins underlie all biological processes. The question is how? The PFF module will help you puzzle over this question: the fields of protein folding, engineering and design are in their infancies, and we have much to learn before we fully understand and can manipulate proteins. What is clear, however, is that protein structure is central to protein function. This module will provide a sense of how protein structures are related to each other and of how these structures relate to protein function. More importantly, however, this module will equip you with the necessary knowledge and skills to allow you to learn about and appreciate the remarkable class of molecule.

The first part of the PFF module necessarily re-covers some of the subject matter visited in first and second-year modules. However, aspects of protein structure are covered in much more detail. In particular, a number of sessions are used to introduce computational and experimental techniques that are essential for studying proteins. This work provides the basis for the in depth discussion of the evolution of proteins, the specifics of protein functions such as protein interactions and protein regulation and finally how proteins fold and how misfolding can lead to disease.

Teaching

100%: Lecture

Assessment

30%: Coursework (Report)
70%: Examination (Unseen examination)

Contact hours and workload

This module is approximately 150 hours of work. This breaks down into about 22 hours of contact time and about 128 hours of independent study. The University may make minor variations to the contact hours for operational reasons, including timetabling requirements.

This module is running in the academic year 2020/21. We also plan to offer it in future academic years. It may become unavailable due to staff availability, student demand or updates to our curriculum. We’ll make sure to let our applicants know of such changes to modules at the earliest opportunity.

Courses

This module is offered on the following courses: