Cell Signalling and its Applications in Therapeutics and Disease (Level 7) (844C1)
15 credits, Level 7 (Masters)
The aim of this module will be to discuss the major signalling pathways in cells and how perturbations of these can result in a loss of growth control and cancer. The module will demonstrate how a knowledge of these pathways has led to the design and use of specific pharmacological agents to target these pathways for therapeutic intervention. The signalling pathways covered will include WNT, hedgehog, LMTK3, RTK, ERK, PI-3-kinase, PKB, mTOR, Jak/Stat pathways and integrin signalling in angiogenesis. A particular focus will be made on breast cancer, the tumour micro-environment, glioblastoma and therapeutic interventions.
5%: One-to-one (Tutorial)
5%: Seminar (Class)
30%: Coursework (Test)
70%: Examination (Unseen examination)
Contact hours and workload
This module is 150 hours of work. This breaks down into 37 hours of contact time and 113 hours of independent study.
This module is running in the academic year 2019/20. We also plan to offer it in future academic years. It may become unavailable due to staff availability, student demand or updates to our curriculum. We’ll make sure to let our applicants know of such changes to modules at the earliest opportunity.