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Publication Type J
Authors Chumkaew, P; Kato, S; Chantrapromma, K
Author Full Name Chumkaew, P; Kato, S; Chantrapromma, K
Title A new triterpenoid ester from the fruits of Bruguiera parviflora
Source CHEMICAL & PHARMACEUTICAL BULLETIN
Language English
Document Type Article
Author Keywords Bruguiera parviflora; rhizophoraceae; triterpenoid ester; antimalarial
Keywords Plus DIOSPYROS-MARITIMA; CHEMICAL-SHIFTS; LUPANE; C-13; H-1; NMR
Abstract A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 mug/ml, but compound 2 was inactive.
Author Address Walailak Univ, Sch Sci, Nakhon Si Thammarat 80160, Taiwan; Seikei Univ, Fac Engn, Dept Appl Chem, Musashino, Tokyo 1808633, Japan
Reprint Address Chantrapromma, K (reprint author), Walailak Univ, Sch Sci, Nakhon Si Thammarat 80160, Taiwan.
E-mail Address ckan@wu.ac.th
Cited References Alvarenga N, 2000, FITOTERAPIA, V71, P719, DOI 10.1016/S0367-326X(00)00217-3; AMMANN W, 1982, ORG MAGN RESONANCE, V20, P260, DOI 10.1002/mrc.1270200414; BOONYAPRAPHAT N, 1998, THAI MED PLANTS, V2, P157; Chang CI, 1998, CHEM PHARM BULL, V46, P1627; CHANTRAPROMMA K, 2004, ACTA CRYSTALLOGR E, V60, P312; Chumkaew P, 2003, J NAT PROD, V66, P540, DOI 10.1021/np0204489; DESJARDINS RE, 1979, ANTIMICROB AGENTS CH, V16, P710; Kuo YH, 1997, PLANTA MED, V63, P363, DOI 10.1055/s-2006-957703; Laphookhieo S, 2004, PHYTOCHEMISTRY, V65, P507, DOI 10.1016/j.phytochem.2003.10.019; Pereira FBM, 1996, NAT PROD LETT, V8, P97, DOI 10.1080/10575639608043247; REYNOLDS WF, 1986, TETRAHEDRON, V42, P3419, DOI 10.1016/S0040-4020(01)87309-9; TRAGER W, 1976, SCIENCE, V193, P673, DOI 10.1126/science.781840
Cited Reference Count 12
Times Cited 14
Total Times Cited Count (WoS, BCI, and CSCD) 15
Publisher PHARMACEUTICAL SOC JAPAN
Publisher City TOKYO
Publisher Address 2-12-15 SHIBUYA, SHIBUYA-KU, TOKYO, 150-0002, JAPAN
ISSN 0009-2363
29-Character Source Abbreviation CHEM PHARM BULL
ISO Source Abbreviation Chem. Pharm. Bull.
Publication Date JAN
Year Published 2005
Volume 53
Issue 1
Beginning Page 95
Ending Page 96
Digital Object Identifier (DOI) 10.1248/cpb.53.95
Page Count 2
Web of Science Category Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy
Subject Category Pharmacology & Pharmacy; Chemistry
Document Delivery Number 887TS
Unique Article Identifier WOS:000226329000020
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