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Publication Type J
Authors Xu, R; Li, XM; Wang, BG
Author Full Name Xu, Rui; Li, Xiao-Ming; Wang, Bin-Gui
Title Penicisimpins A-C, three new dihydroisocoumarins from Penicillium simplicissimum MA-332, a marine fungus derived from the rhizosphere of the mangrove plant Bruguiera sexangula var. rhynchopetala
Source PHYTOCHEMISTRY LETTERS
Language English
Document Type Article
Author Keywords Mangrove rhizosphere; Marine-derived fungus; Penicillium simplicissimum; Dihydroisocoumarins; Antimicrobial activity
Keywords Plus NATURAL-PRODUCTS; PAECILOMYCES-VARIOTII; BRINE SHRIMP
Abstract Three new dihydroisocoumarin derivatives, penicisimpins A-C (1-3), were isolated and identified from Penicillium simplicissimum MA-332, a fungus derived from the rhizosphere of the marine mangrove plant Bruguiera sexangula var. rhynchopetala. Their structures and absolute configurations were elucidated by extensive spectroscopic methods in combination with X-ray diffraction experiment. Compounds 1-3 exhibited brine shrimp (Artemia salina) lethality as well as broad-spectrum antimicrobial activities. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
Author Address [Xu, Rui; Li, Xiao-Ming; Wang, Bin-Gui] Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China; [Xu, Rui] Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China
Reprint Address Wang, BG (reprint author), Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China.
E-mail Address wangbg@ms.qdio.ac.cn
Funding Agency and Grant Number National Natural Science Foundation of China [31570356]
Funding Text Financial support from the National Natural Science Foundation of China (31570356) is gratefully acknowledged.
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Cited Reference Count 18
Publisher ELSEVIER SCIENCE BV
Publisher City AMSTERDAM
Publisher Address PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
ISSN 1874-3900
29-Character Source Abbreviation PHYTOCHEM LETT
ISO Source Abbreviation Phytochem. Lett.
Publication Date SEP
Year Published 2016
Volume 17
Beginning Page 114
Ending Page 118
Digital Object Identifier (DOI) 10.1016/j.phytol.2016.07.003
Page Count 5
Web of Science Category Plant Sciences; Oncology
Subject Category Plant Sciences; Oncology
Document Delivery Number EE3TM
Unique Article Identifier WOS:000389521400020
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