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Version 3.18
Publication Type J
Authors Mroczek, A
Author Full Name Mroczek, Agnieszka
Title Phytochemistry and bioactivity of triterpene saponins from Amaranthaceae family
Language English
Document Type Article
Author Keywords Anticancer tritepenoids; Chenopodiaceae; Nutraceuticals; Oleanolic acid; Phytochemicals
Abstract The family Amaranthaceae comprises more than 175 genera and 2,000 species of herbs, shrubs, subshrubs and small trees. It is a widespread and cosmopolitan family that can be found from the tropics to cool temperate regions. Some of the Amaranthaceae plants have economic importance and are used as herbal medicines or vegetables in various parts of the globe. The phytochemical profile of Amaranthaceae plants comprises essential oils, betalains, phenolic compounds and terpenoids. This review focuses on distribution, structure and pharmacological properties of triterpene saponins present in Amaranthaceae plants. These include oleanane-, ursane- and lupane-type of compounds possessing a very broad array of structures. Different pattern of triterpene saponin occurrence was characterised in almost 30 species belonging to Amaranthaceae family, i.e. Achyranthes bidendata Blume, Achyranthes faureri L,veille. & Vahiot., Amaranthus caudatus L., Amaranthus cruentus L., Amaranthus hypochondriacus L., Alternanthera philoxeroides Griseb., Alternanthera repens L., Anabasis articulata Moq, Anabasis setifera Moq, Atriplex glauca L., Atriplex semibaccata R. Br., Bassia muricata L., Beta vulgaris var. vulgaris L., Gomphrena globosa Spreng., Celosia argentea L., Celosia cristata L., Chenopodium album L., Chenopodium foliosum L., Chenopodium quinoa Willd., Climacoptera obtusifolia L., Kochia scoparia L., Pfaffia glomerata Speng., Pfaffia paniculata Mart., Salicornia bigelovii Torr., Salicornia europaea L., Salicornia herbacea L. The bioactivity of saponin mixtures or individual saponins in vitro and in vivo include cytotoxic, immunomodulatory, hepatoprotective, antidiabetic, hypolipidemic, antiosteoporosis, antiviral, antifungal as well as anthelmintic actions. Herbal and edible Amaranthaceae plants can be considered as promising and highly available sources of biologically active triterpene saponins.
Author Address Univ Warsaw, Dept Plant Biochem, Fac Biol, PL-02960 Warsaw, Poland
Reprint Address Mroczek, A (reprint author), Univ Warsaw, Dept Plant Biochem, Fac Biol, Miecznikowa St 1, PL-02960 Warsaw, Poland.
E-mail Address mroczek@biol.uw.edu.pl
Funding Agency and Grant Number European Social Fund (ESF) [POKL.04.03.00-00-060/12]
Funding Text The participation in the Phytochemical Society of Europe meeting in Romania was founded by the grant from the European Social Fund (ESF) project POKL.04.03.00-00-060/12.
Cited References Abdou AM, 2013, ARCH PHARM RES, V36, P715, DOI 10.1007/s12272-013-0075-9; Adewale Adetutu, 2013, Pharmacognosy Res, V5, P300, DOI 10.4103/0974-8490.118819; Ando H, 2008, J NAT MED, V62, P57, DOI 10.1007/s11418-007-0183-2; Bagavan A, 2008, PARASITOL RES, V103, P223, DOI 10.1007/s00436-008-0962-z; Biancardi E, 2012, BETA MARITMA: THE ORIGIN OF BEETS, P1, DOI 10.1007/978-1-4614-0842-0; BURNOUFRADOSEVICH M, 1985, PHYTOCHEMISTRY, V24, P2063, DOI 10.1016/S0031-9422(00)83122-2; Cheok CY, 2014, FOOD RES INT, V59, P16, DOI 10.1016/j.foodres.2014.01.057; CUADRADO C, 1995, J SCI FOOD AGR, V67, P169, DOI 10.1002/jsfa.2740670205; Das AK, 2012, ASIAN PAC J TROP MED, V5, P197, DOI 10.1016/S1995-7645(12)60024-8; Dinda B, 2004, INDIAN J CHEM B, V43, P2223; Dini I, 2001, J AGR FOOD CHEM, V49, P741, DOI 10.1021/jf000971y; Doligalska M, 2011, VET PARASITOL, V179, P144, DOI 10.1016/j.vetpar.2011.01.053; Escudero NL, 2011, J FOOD BIOCHEM, V35, P1327, DOI 10.1111/j.1745-4514.2010.00454.x; Estrada A, 1998, COMP IMMUNOL MICROB, V21, P225, DOI 10.1016/S0147-9571(97)00030-1; Fukumura M, 2009, J NAT MED, V02, P63181; Girija K., 2011, Asian Pacific Journal of Tropical Biomedicine, V1, P133, DOI 10.1016/S2221-1691(11)60011-7; Gohar AA, 2002, Z NATURFORSCH C, V57, P597; Han LK, 2006, PHYTOTHER RES, V20, P877, DOI 10.1002/ptr.1981; Henry Max, 2005, Phytochemistry Reviews, V4, P89, DOI 10.1007/s11101-005-3861-2; Hoshino T, 2013, J NAT MED-TOKYO, V67, P386, DOI 10.1007/s11418-012-0684-5; IDA Y, 1995, CHEM PHARM BULL, V43, P896; IDA Y, 1994, PLANTA MED, V60, P286, DOI 10.1055/s-2006-959481; Ida Y, 1998, BIOORG MED CHEM LETT, V8, P2555, DOI 10.1016/S0960-894X(98)00457-0; IDA Y, 1994, TETRAHEDRON LETT, V35, P6887, DOI 10.1016/0040-4039(94)85032-1; Jabrane A, 2011, MAGN RESON CHEM, V49, P83, DOI 10.1002/mrc.2696; Judd WS, 1999, PLANT SYSTEMATICS PH; Junkuszew M, 1998, PHYTOCHEMISTRY, V49, P195, DOI 10.1016/S0031-9422(97)00904-7; Kambouche N, 2009, AFR J BIOTECHNOL, V8, P5589; Kamel MS, 2001, PHYTOCHEMISTRY, V57, P1259, DOI 10.1016/S0031-9422(01)00240-0; Kedereit G, 2003, INT J PLANT SCI, V164, P959; Kim YA, 2012, BIOORG MED CHEM LETT, V22, P4318, DOI 10.1016/j.bmcl.2012.05.017; KOHDA H, 1991, CHEM PHARM BULL, V39, P2609; Kraujalis P, 2013, PLANT FOOD HUM NUTR, V68, P322, DOI 10.1007/s11130-013-0375-8; Kuljanabhagavad T, 2008, PHYTOCHEMISTRY, V69, P1919, DOI 10.1016/j.phytochem.2008.03.001; Lavaud Catherine, 2000, Fitoterapia, V71, P338, DOI 10.1016/S0367-326X(99)00166-5; Li J, 2010, PLANTA MED, V76, P635, DOI 10.1055/s-0029-1240631; Li JT, 2009, J INTEGR PLANT BIOL, V51, P122, DOI 10.1111/j.1744-7909.2008.00764.x; Li YJ, 2010, RAPID COMMUN MASS SP, V24, P2975, DOI 10.1002/rcm.4728; Lopez VRL, 2011, PLANT FOOD HUM NUTR, V66, P157, DOI 10.1007/s11130-011-0218-4; Madl T, 2006, J AM SOC MASS SPECTR, V17, P795, DOI 10.1016/j.jasms.2006.02.013; Gomez-Caravaca AM, 2011, J AGR FOOD CHEM, V59, P10815, DOI 10.1021/jf202224j; Mastebroek HD, 1995, J SCI FOOD AGR, V67, P169; Matsuda H, 1999, J PHARMACOL EXP THER, V289, P729; Metwally N. S., 2012, Journal of Applied Pharmaceutical Science, V2, P54; Mroczek A, 2012, J AGR FOOD CHEM, V60, P12397, DOI 10.1021/jf303952x; Muller K, 2005, ANN MO BOT GARD, V92, P66; Murakami T, 1999, CHEM PHARM BULL, V47, P1717; Nakamura S, 2010, CHEM PHARM BULL, V58, P690, DOI 10.1248/cpb.58.690; Nana FW, 1998, PHYTOCHEMISTRY, V49, P195; Nedialkov PT, 2012, NAT PROD COMMUN, V7, P1419; NG KG, 1994, FOOD CHEM, V49, P311, DOI 10.1016/0308-8146(94)90177-5; Ninfali P, 2013, FITOTERAPIA, V89, P188, DOI 10.1016/j.fitote.2013.06.004; Oleszek W, 1999, J AGR FOOD CHEM, V47, P3685, DOI 10.1021/jf990182k; Oleszek W, 2006, J CHROMATOGR A, V1112, P78, DOI 10.1016/j.chroma.2006.01.037; Pang X, 2014, J ASIAN NAT PROD RES, V16, P240, DOI 10.1080/10286020.2013.879120; Podolak I, 2010, PHYTOCHEM REV, V9, P425, DOI 10.1007/s11101-010-9183-z; Pushpa Latha B, 2011, AFR J BIOTECHNOL, V10, P7038; Rahmatullah M, 2013, AFR J TRADIT COMPLEM, V10, P408, DOI 10.4314/ajtcam.v10i5.31; RASTRELLI L, 1995, J AGR FOOD CHEM, V43, P904, DOI 10.1021/jf00052a011; Rattanathongkom A, 2009, PLANTA MED, V75, P829, DOI 10.1055/s-0029-1185436; Ren X. C., 2011, CHINESE J EXPT TRADI, V17, P128; Salvador MJ, 2002, PHYTOMEDICINE, V9, P566, DOI 10.1078/09447110260573227; Sanoko R, 1999, PHYTOCHEMISTRY, V51, P1043, DOI 10.1016/S0031-9422(99)00046-1; Shaker KH, 2003, Z NATURFORSCH C, V58, P485; Simpson MG, 2010, PLANT SYSTEMATICS, P301; Sparg SG, 2004, J ETHNOPHARMACOL, V94, P219, DOI 10.1016/j.jep.2004.05.016; Steffensen SK, 2011, J AGR FOOD CHEM, V59, P12073, DOI 10.1021/jf202969e; Stevens P. F., 2001, ANGIOSPERM PHYLOGENY; Stintzing FC, 2004, Z NATURFORSCH C, V59, P1; Sun HX, 2006, VACCINE, V24, P3432, DOI 10.1016/j.vaccine.2006.02.014; Sun ZL, 2011, FITOTERAPIA, V82, P591, DOI 10.1016/j.fitote.2011.01.007; Vincken JP, 2007, PHYTOCHEMISTRY, V68, P275, DOI 10.1016/j.phytochem.2006.10.008; [王广树 Wang Guangshu], 2005, [中国药物化学杂志, Chinese Journal of Medicinal Chemistry], V15, P224; Wang QZ, 2012, FITOTERAPIA, V83, P742, DOI 10.1016/j.fitote.2012.02.013; Wang Y, 2010, FITOTERAPIA, V81, P1246, DOI 10.1016/j.fitote.2010.08.011; Wei HL, 2012, CHIN J NAT MEDICINES, V10, P98, DOI 10.3724/SP.J.1009.2012.00098; Whang W-K, 1991, ARCH PHARM RES, V14, P176, DOI 10.1007/BF02892025; Woldemichael GM, 2001, J AGR FOOD CHEM, V49, P2327, DOI 10.1021/jf0013499; Wu QB, 2011, CHEM PHARM BULL, V59, P666, DOI 10.1248/cpb.59.666; Xue QA, 2011, NAT PROD RES, V25, P772, DOI 10.1080/14786410902833948; Yao Y, 2014, J FOOD SCI, V79, pH1018, DOI 10.1111/1750-3841.12425; Yeskaliyeva B, 2006, PHYTOCHEMISTRY, V67, P2392, DOI 10.1016/j.phytochem.2006.07.003; Yin M, 2012, CHEM NAT COMPD+, V48, P258, DOI 10.1007/s10600-012-0216-2; Yoshikawa M, 1997, CHEM PHARM BULL, V45, P1300; Yoshikawa M, 1998, CHEM PHARM BULL, V46, P1758; Yoshikawa M, 1996, CHEM PHARM BULL, V44, P1212; Zhao YH, 2014, FOOD CHEM, V151, P101, DOI 10.1016/j.foodchem.2013.11.030; Zhu NQ, 2002, J AGR FOOD CHEM, V50, P865, DOI 10.1021/jf011002l
Cited Reference Count 88
Times Cited 4
Total Times Cited Count (WoS, BCI, and CSCD) 4
Publisher SPRINGER
Publisher City DORDRECHT
ISSN 1568-7767
29-Character Source Abbreviation PHYTOCHEM REV
ISO Source Abbreviation Phytochem. Rev.
Publication Date AUG
Year Published 2015
Volume 14
Issue 4
Special Issue SI
Beginning Page 577
Ending Page 605
Digital Object Identifier (DOI) 10.1007/s11101-015-9394-4
Page Count 29
Web of Science Category Plant Sciences
Subject Category Plant Sciences
Document Delivery Number CN4PG
Unique Article Identifier WOS:000358411700003
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