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Publication Type J
Authors Prakash, S; Ramasubburayan, R; Ramkumar, VS; Kannapiran, E; Palavesam, A; Immanuel, G
Author Full Name Prakash, Santhiyagu; Ramasubburayan, Ramasamy; Ramkumar, Vijayan Sri; Kannapiran, Ethiraj; Palavesam, Arunachalam; Immanuel, Grasian
Title In vitro-Scientific evaluation on antimicrobial, antioxidant, cytotoxic properties and phytochemical constituents of traditional coastal medicinal plants
Source BIOMEDICINE & PHARMACOTHERAPY
Language English
Document Type Article
Author Keywords CMP's; Antimicrobials; Antioxidants; Hemolytic properties
Keywords Plus SOUTHWEST COAST; EXTRACTS; INDIA; BARK; L.
Abstract In the present study, evaluation of antimicrobial, antioxidant, phytochemical constituents and toxicological properties of six coastal medicinal plants (CMP's) such as Ipomea biloba, Cantharanthus roseus, Cymbopogon citratus, Vitex negundo, Thespesia populnea and Pandanus tectorius was done. The maximum antimicrobial activity was recorded by methanolic extracts of V. negundo and T. populnea against bacterial and fungal pathogens. Similarly, methanolic extracts of V. negundo and T. populnea evidenced highest antioxidant properties. The extract of T. populnea showed the maximum cytotoxicity against Artemia salina with the LC50 value of 478.11 mu g/ml. The hemolytic property of CMP's extracts was V. negundo (8.91%), T. populnea (21%) and C. citratus (64%) also the hemolytic index did not show any hemolysis of human erythrocytes. Furthermore, the TLC separation of V. negundo and T. populnea extracts exhibited the presence of Flavonoids (Rf-0.74) and Terpenoids (Rf-0.64). The present findings propose the promising clinical applications of selected CMP's. (C) 2016 Elsevier Masson SAS. All rights reserved.
Author Address [Prakash, Santhiyagu] Sri Kalishwari Coll Autonomous, Dept Biotechnol, Virudunagar 626123, Tamil Nadu, India; [Prakash, Santhiyagu] SRM Univ, Res Inst, Kattankulathur 603203, Tamil Nadu, India; [Ramasubburayan, Ramasamy; Immanuel, Grasian] Manonmaniam Sundaranar Univ, Ctr Marine Sci & Technol, Rajakkamangalam 629502, Tamil Nadu, India; [Ramkumar, Vijayan Sri] Bharathidasan Univ, Dept Environm Biotechnol, Sch Environm Sci, Tiruchchirappalli 620024, Tamil Nadu, India; [Kannapiran, Ethiraj] Alagappa Univ, Dept Anim Hlth Management, Sci Campus, Karaikkudi 630004, Tamil Nadu, India; [Palavesam, Arunachalam] Manonmaniam Sundaranar Univ, Dept Anim Sci, Abishekapatti 627012, Tamil Nadu, India
Reprint Address Prakash, S (reprint author), Sri Kalishwari Coll Autonomous, Dept Biotechnol, Virudunagar 626123, Tamil Nadu, India.
E-mail Address algaprakash@gmail.com
Cited Reference Count 39
Times Cited 6
Total Times Cited Count (WoS, BCI, and CSCD) 6
Publisher ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Publisher City ISSY-LES-MOULINEAUX
Publisher Address 65 RUE CAMILLE DESMOULINS, CS50083, 92442 ISSY-LES-MOULINEAUX, FRANCE
ISSN 0753-3322
29-Character Source Abbreviation BIOMED PHARMACOTHER
ISO Source Abbreviation Biomed. Pharmacother.
Publication Date OCT
Year Published 2016
Volume 83
Beginning Page 648
Ending Page 657
Digital Object Identifier (DOI) 10.1016/j.biopha.2016.07.019
Page Count 10
Web of Science Category Medicine, Research & Experimental; Pharmacology & Pharmacy
Subject Category Research & Experimental Medicine; Pharmacology & Pharmacy
Document Delivery Number EF6IC
Unique Article Identifier WOS:000390433400078
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