Research Fellow Ref 4929
School/department:School of Life Sciences
Hours: full time or part time up to a maximum of 1FTE. Requests for flexible working options will be considered (subject to business need).
Contract: fixed term until November 2021
Salary: Starting at £33,797 to £40,322 per annum, pro rata if part time
Placed on: 9 November 2020
Closing date: 9 December 2020 Applications must be received by midnight of the closing date.
Expected start date: January 2021
We wish to appoint a postdoctoral researcher to work on a BBSRC-funded project entitled “Understanding and exploiting general transcription factors in the antibiotic producing Streptomyces”. The research will be conducted in the laboratory of Dr Mark Paget within the School of Life Sciences.
The project aims to understand how general transcription factors influence global shifts in gene expression, including the switch to antibiotic production. We will use this new knowledge to develop new ways of activating “cryptic” antibiotic biosynthetic gene clusters that are poorly expressed or silent during laboratory growth. The work is therefore highly relevant to the discovery of new antibiotics to meet the global challenge of antimicrobial resistance (AMR).
You will have a thorough working knowledge of laboratory techniques including genetic manipulation and protein expression and purification. The research will involve next-generation sequencing approaches and so bioinformatics experience is desirable. You will have a PhD in a relevant subject area and an experimental laboratory background is essential. You should be an enthusiastic and innovative scientist, a good team-worker and an excellent communicator.
The post might be extended for up to 6 months subject to funding
Please contact Dr Mark Paget email@example.com for informal enquiries.
How to apply
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