Postdoctoral Research Fellow – Molecular mechanisms of chromosome stability Ref 0683

School/department: School of Life Sciences
Hours: Full time or part time hours considered. Requests for flexible working options will be considered (subject to business need).
Contract: Fixed term for 2 years initially
Reference: 0683
Salary: Starting at £33,199 and rising to £39,609 per annum, pro rata
Placed on: 29 January 2019 
Closing date: 28 February 2019. Applications must be received by midnight of the closing date.
Expected start date: As soon as possible

Job description

A postdoctoral fellowship is available immediately to study fundamental questions of genome stability.

Using the tractable yeast model, we have recently gained novel insight into how cells maintain the structural integrity of chromosomes when genome replication is perturbed and/or DNA double-strand breaks occur (Ölmezer et al. (2016) Nature Communications 7:13157; Mattarocci et al. (2017) Nature Structural & Molecular Biology 24:588-595).

The successful candidate will use a combination of molecular genetics and analysis of DNA intermediates to mechanistically elucidate these conserved processes, with important biomedical implications for our understanding and therapeutic exploitation of genome instability in cancer.

Candidates with a proven track record in genome stability (first authorship publication) are encouraged to apply.

This post is funded for 2 years initially. Applicants should have extensive experience with S. cerevisiae molecular genetics and cell-based assays, while experience with human cell culture is a plus.

The successful candidate will join the Genome and Stability Centre, an internationally renowned institute within the School of Life Sciences, carrying out research on cellular responses to DNA damage and their impact on genome instability and disease.

We provide a stimulating and supportive research environment and our expertise covers a wide range of experimental systems. An overview of research interests can be found at the Rass Lab.

The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014.

The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Silver Award.

Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in Science, Technology, Engineering, Medicine and Mathematics (STEMM) at Sussex.

The School of Life Sciences welcomes applications to academic posts from candidates who wish to work part-time or as job-sharers.

The University offers various schemes to provide real benefits to parents, these can be found at Family Friendly Policies

Download job description and person specification Ref 0683 [PDF 135.61KB]

How to apply

Download our academic post application form [DOC 301.50KB] and personal details and equal opportunities form [DOC 162.50KB] and fill in all sections.

Application forms should be accompanied by a full CV, a statement of research interests and aspirations (up to a total of 4 pages), and the names of two academic referees.

Informal enquiries are welcome and should be sent to Prof. Ulrich Rass at

Email your completed application, and personal details and equal opportunities form, to 

You should attach your application form and all documents to the email (don't use a web-based upload/weblink service) and use the format job reference number / job title / your name in the subject line.

You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.

Download our terms and conditions summary for Research Faculty Terms and Conditions [DOC 36.00KB]

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