Postdoctoral Research Fellow (PDRA) Ref A0003

School/department: School of Life Sciences / Genome Damage and Stability Centre     
Hours: full time or part time hours considered up to a maximum of 1 FTE.
Requests for flexible working options will be considered (subject to business need).
Location: Brighton, United Kingdom
Contract: Fixed term for 3 years  
Reference: A0003
Salary: Starting at £36,333 to £43,155 per annum, pro rata if part time
Placed on: 17 February 2023
Closing date:  17 March 2023. Applications must be received by midnight of the closing date.
Expected interview date: To be confirmed
Expected start date: Flexible start dates from March 2023 to Dec 2023

Job description

Two post-doctoral research positions are available in the laboratory of Prof. Matthew Neale in the Genome Damage and Stability Centre for a period of 3 years. These positions are supported by an 8-year Wellcome Trust Discovery Award which provides capacity for long-term postdoctoral training and development.

We are a team seeking to understand the molecular mechanisms that underpin the process of genetic recombination and how this intersects with both local and genome-scale changes in chromosome structure. We will use a range of single-cell model organisms and techniques, and apply discoveries to enrich our fundamental understanding of genetic variation, chromosome segregation and aneuploidy across all species including humans.

You are a creative, conscientious, and responsible team player who can both work independently and who can contribute to the development of a broad research vision through team working and by forging internal and external collaborations.

You will have recent PhD and/or postdoctoral expertise in methods including molecular biology, genetics, chromosome conformation capture (Hi-C), ChIP-seq, super-resolution microscopy, and in the bioinformatic skills associated with interrogating complex datasets.

You will be able to demonstrate how you have applied your experience to answer key biological questions—and are now seeking the opportunity to explore open-ended research in which you will take a major role in project development, discovery and dissemination.

 Alongside your research projects, you will receive 10 days per year for professional development—enabling us to nurture you to become one of the next generation of research leaders, and giving you the time and the opportunity to harness your potential.

 For an overview of research in the Neale lab visit:

Recent research from our team includes the analysis of chromosome conformation in meiosis ( and mitosis (https://pubmed.ncbi.nlm.
), development of methods to interrogate in vivo Topoisomerase activity (, and elucidation of the molecular regulation of the evolutionarily conserved Spo11 enzyme during DNA double-strand break formation (;

Applications including a full CV, a statement of research interests and aspirations, and letters of support (and/or named referees) should be sent to

You are encouraged to contact Matt Neale informally for further discussion and information.

The School of Life Sciences at the University of Sussex is at the forefront of research in the UK. In the recent Research Excellence Framework assessment (REF 2021), 100% of our Impact cases in Biological Sciences and Chemistry were rated as world-leading or internationally excellent. The School has received substantial recent University investment and is embarking on an exciting and extensive, muti-million pound refurbishment and improvement project.

Based in the School of Life Sciences, the Genome Damage and Stability Centre  (, is an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease. We provide a stimulating and supportive environment and our expertise covers a range of experimental systems.

The School of Life Sciences is committed to increasing the diversity of its staff and providing an inclusive working environment. The School currently holds an Athena SWAN Silver Award, has developed a Race Equity Action Plan, and hosts an active Equality, Diversity and Inclusion working group.

Applications are particularly welcomed from Black and minority ethnic candidates, and women, trans and non-binary candidates, who are under-represented in the School of Life Sciences.

Applications to posts from candidates who wish to work part-time or as job-sharers are welcome.

The University offers various schemes to provide real benefits to parents, these can be found at Family Friendly Policies

The University is committed to equality and valuing diversity, and applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in Science, Technology, Engineering, Medicine and Mathematics (STEMM) at Sussex.

The University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds.

You can find out more about our values and our EDI Strategy,  Inclusive Sussex, on our webpages.

Download job description and person specification Ref A0003 [PDF 245.93KB]

The University requires that work undertaken for the University is performed from the UK. 

Visa Sponsorship Queries:

"This role has been assigned an eligible SOC code however to meet the minimum salary requirement this is dependent on the salary you are offered and/or whether you are eligible for tradeable points. If you require visa sponsorship from the University of Sussex to undertake this role please consult our Skilled Worker Visa information page for further information. If you want further advice on sponsorship eligibility please contact

 “Please note that this position may be subject to ATAS clearance if you require visa sponsorship.” 

How to apply

Download our academic application form [DOC 199.50KB] and Personal Details and Equal Opportunities Form [DOC 119.50KB] and fill in all sections.

Email your completed application, personal details and equal opportunities form, full CV, a statement of research interests and aspirations, and letters of support (and/or named referees), to

You should attach your application form and all documents to the email in PDF format (we are unable to accept applications as or .pages) and use the format job reference number / job title / your name in the subject line.

You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.

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