Genome damage and stability (2016 entry)

Subject overview

  • The Genome Damage and Stability Centre is internationally renowned for basic research into genome instability and its relationship to human diseases such as cancer and neurodegeneration. The Centre is an MRC Centre of Excellence, located within the School of Life Sciences, with 20 highly active
    research groups led by eminent scientists including Fellows of the Academy of Medical Sciences and the Royal Society.
  • We attract high-quality scientists from all over the world and provide world-class training for doctoral students in a supportive and collegial atmosphere.
  • We are a centre of excellence facilitating the translation of basic scientific discovery into the delivery of novel treatments. Sussex is part of the Barts and Brighton Experimental Cancer Medicine Centre (ECMC), driving the development of new anti-cancer treatments across the UK.

ECMC logo

Programmes

  • PhD in Genome Stability
  • MPhil in Genome Stability

The School of Life Sciences is a vibrant international research community. We offer MPhil and PhD courses and welcome discussion with applicants on potential projects falling within our research interests.

The Genome Damage and Stability Centre enables scientists of different disciplines to be housed in one building and to benefit from mutual interests. Our work ranges from studies on the protein molecules that repair DNA inside cells to the genes that are altered or mutated in cancer cells and in neurological disease, with the aim of understanding these diseases and how we might defeat them.

Student progress and support 

Throughout your studies, you are expected to take part in laboratory meetings, journal clubs and a weekly seminar series. We encourage all students to participate in national and international scientific meetings.

The School offers full support to all research students by monitoring their research progress in the form of annual reviews, informal meetings and mid-year reports (Year 1). The annual Postgraduate Research Colloquium brings doctoral students and faculty together for a wider discussion of research projects within the School. All third-year doctoral students give a talk on their research, and all second-year students submit a poster depicting the key aims and objectives, methods and findings of their project.

We aim to ensure that you have the best possible research experience. The relationships between supervisors and research students are among the most rewarding of academic partnerships. We also host regular social events for our students to mingle with their peers and supervisors across the biosciences. We take student feedback seriously and doctoral students are represented on our Student Experience Committee.

Entry requirements

MPhil in Genome Stability

UK entrance requirements

A first- or upper second-class undergraduate honours degree in a relevant science subject

Overseas entrance requirements

If your country is not listed below, please contact the University at E pg.enquiries@sussex.ac.uk

If you have any questions about your qualifications after consulting our overseas qualifications, contact the University at E pg.enquiries@sussex.ac.uk

English language requirements

IELTS 6.5, with not less than 6.0 in each section. Pearson Test of English (Academic) 62 overall, with at least 56 in all four skills

For more information, refer to What qualifications do I need?

Additional entry information

If you are a non-EEA or Swiss national you must obtain clearance by the UK Government Academic Technology Approval Scheme (ATAS) for this degree. Please ensure you allow sufficient time for your University application to be processed in time for you to apply for ATAS clearance (and a Tier 4 Student Visa if appropriate). Find out more about ATAS.

PhD in Genome Stability

UK entrance requirements

A first- or upper second-class undergraduate honours degree in a relevant science subject

Overseas entrance requirements

If your country is not listed below, please contact the University at E pg.enquiries@sussex.ac.uk

If you have any questions about your qualifications after consulting our overseas qualifications, contact the University at E pg.enquiries@sussex.ac.uk

English language requirements

IELTS 6.5, with not less than 6.0 in each section.

For more information, refer to What qualifications do I need?

Additional entry information

If you are a non-EEA or Swiss national you must obtain clearance by the UK Government Academic Technology Approval Scheme (ATAS) for this degree. Please ensure you allow sufficient time for your University application to be processed in time for you to apply for ATAS clearance (and a Tier 4 Student Visa if appropriate). Find out more about ATAS.

Visas and immigration

Find out more about Visas and immigration.

For more information about the admissions process at Sussex

For pre-application enquiries:

Student Recruitment Services
T +44 (0)1273 876787
E pg.enquiries@sussex.ac.uk

For post-application enquiries:

Postgraduate Admissions,
University of Sussex,
Sussex House, Falmer,
Brighton BN1 9RH, UK
T +44 (0)1273 877773
F +44 (0)1273 678545
E pg.applicants@sussex.ac.uk 

Fees and funding

Fees

MPhil in Genome Stability fees

Home UK/EU students: £4,1211
Overseas students: £18,3002

1 The fee shown is for the academic year 2016.
2 The fee shown is for the academic year 2016.

PhD in Genome Stability fees

Home UK/EU students: £4,1211
Overseas students: £18,3002

1 The fee shown is for the academic year 2016.
2 The fee shown is for the academic year 2016.

Find out more about fees

Visit Living costs

Scholarships

The sources of financial support listed below are for the subject area you are viewing and may not apply to all degrees listed within it. Please check the description of the individual source of financial support to make sure it is relevant to your chosen degree.

Visit Postgraduate research scholarships 2016

Visit Career development and part-time work

We are in the process of updating funding sources for postgraduate study in the academic year 2016/17. For general information, visit Postgraduate research scholarships 2016.

For more information on scholarships go to the Scholarships web pages.

Faculty interests

Prof Bugewa Apampa
Professor of Pharmacy Education
B.Apampa@sussex.ac.uk

Research interests: Dementia, Education, Pharmaceutical care, Pharmacy

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Dr John Armstrong
Senior Lecturer in Biochemistry
J.Armstrong@sussex.ac.uk

Research interests: Genetic manipulation

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Prof John Atack
Professor of Molecular Pharmacology
J.Atack@sussex.ac.uk

Research interests: Alzheimer's Disease, Drug discovery, Neuropharmacology, Neuroscience, Pharmacology, Schizophrenia

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Dr Jon Baxter
Research Fellow
Jon.Baxter@sussex.ac.uk

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Dr Alessandro Bianchi
Senior Lecturer
A.Bianchi@sussex.ac.uk

Research interests: DNA replication, Telomerase, Telomeres

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Prof Keith Caldecott
Professor of Biochemistry 'Royal Society Wolfson Research Merit Award Holder'
K.W.Caldecott@sussex.ac.uk

Research interests: Ageing, Drug discovery, Mitosis, Neurodegeneration, Proteomics

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Prof Antony Carr
Director
A.M.Carr@sussex.ac.uk

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Dr Neil Crickmore
Senior Lecturer in Molecular Genetics
N.Crickmore@sussex.ac.uk

Research interests: Bioinformatics, Biological control, Insecticides

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Prof Aidan Doherty
Professor of Biochemistry
A.J.Doherty@sussex.ac.uk

Research interests: Cells, Crystallography, DNA, Mitochondria, Molecular chaperones, Pathogens, Polymerase, Structural biology

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Prof Jessica Downs
Visiting Research Fellow
J.A.Downs@sussex.ac.uk

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Dr Georgios Giamas
Reader in Cell Signalling
G.Giamas@sussex.ac.uk

Research interests: Cancer (Human disease), Cancer cell biology, Cell signalling, Drug resistance, Estrogen Receptor, LMTK3, molecular biology, Phosphorylation, Protein kinase, Proteomics, SILAC, Transcription, Xenograft models

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Prof Martin Gosling
Professor of Molecular Pharmacology
M.Gosling@sussex.ac.uk

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Dr Helfrid Hochegger
Reader
H.Hochegger@sussex.ac.uk

Research interests: Cancer cell biology, Cell biology, Cell cycle, Cell division, Drug discovery, Kinases, Mathematical modelling, Mitosis, Proteomics

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Dr Eva Hoffmann
Senior Research Fellow
eh58@sussex.ac.uk

Research interests: age-related infertility, budding yeast, Chromosome pairing, Chromosomes, Cytogenetics, Genetic mapping/ markers, Genetic variation, human oocytes, infertility, Meiosis, mismatch repair, synaptonemal complex

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Dr Penny Jeggo
Professorial Fellow
P.A.Jeggo@sussex.ac.uk

Research interests: Mitosis, Proteomics, Radiation

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Prof Alan Lehmann
Research Professor, Molecular Genetics
A.R.Lehmann@sussex.ac.uk

Research interests: DNA damage and repair, human genetic disorders, Replication of damaged DNA

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Dr Erika Mancini
Reader
Erika.Mancini@sussex.ac.uk

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Prof Anthony Moore
Professor of Biochemistry
A.L.Moore@sussex.ac.uk

Research interests: Plant physiology

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Prof Simon Morley
Professor of Signal Transduction
S.J.Morley@sussex.ac.uk

Research interests: Pathology

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Dr Jo Murray
Reader
J.M.Murray@sussex.ac.uk

Research interests: Cell cycle, Chromosomes, DNA damage and repair, DNA replication, Genome rearrangements, Homologous recombination, Replication of damaged DNA

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Dr Matt Neale
Reader
M.Neale@sussex.ac.uk

Research interests: Chromosome structure, Chromosomes, Meiosis, Recombination

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Prof Mark O'Driscoll
Professor Of Human Molecular Genetics
M.O-Driscoll@sussex.ac.uk

Research interests: Cancer (Human disease), Cancer cell biology, Cell biology, Cell cycle, Cell Differentiation (disease), Cell division, Cell signalling, Chemotherapeutics, Dev. Origins of adult disease, DNA damage and repair, DNA double-strand breaks, DNA replication, Genetics and development, Genotype to Phenotype, Medical science and disease, Metabolic syndrome, Nervous system, Neurodegenerative disease, Neurodevelopmental Syndromes, Neuroscience (Human disease), Paediatrics (Human disease), Pathogenesis, Pathology, Replication of damaged DNA, Signal transduction, Tissue differentiation and programming

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Dr Antony Oliver
Senior Research Fellow
Antony.Oliver@sussex.ac.uk

Research interests: Biomolecules and biochemistry, Biophysics, DNA Binding and interactions, DNA binding proteins, DNA damage and repair, DNA double-strand breaks, Drug development, Drug discovery, Kinases, Protein-DNA interactions, Replication of damaged DNA, Structural biology

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Dr Mark Paget
Reader in Molecular Genetics
M.Paget@sussex.ac.uk

Research interests: Antibiotic resistance, Antibiotics, Biofuels, Gene expression, Metabolic engineering, Microbiology, Renewables, Streptomyces, Transcription

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Prof Laurence Pearl
Professor of Structural Biology
Laurence.Pearl@sussex.ac.uk

Research interests: Chromatin, Crystallography, Drug development, Drug discovery, Medicinal Chemistry, Molecular chaperones, Neurodegeneration, Protein structure, Proteomics, Structural biology

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Dr Chrisostomos Prodromou
Senior Research Fellow
Chris.Prodromou@sussex.ac.uk

Research interests: 3D Structure, Chlamydomonas, Drug discovery, Dynein, Hsp90, molecular biology, Molecular chaperones, Protein expression

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Prof Louise Serpell
Professor of Biochemistry
L.C.Serpell@sussex.ac.uk

Research interests: Alzheimer's Disease, Biomedical neuroscience, Cell biology, Dementia, Drug discovery, Neurodegeneration, Neurodegenerative disease, Protein misfolding, Structural biology, Synthetic biology

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Prof Alison Sinclair
Professor of Molecular Virology
A.J.Sinclair@sussex.ac.uk

Research interests: Burkitt lymphoma, Cancer (Human disease), Cancer cell biology, Cell biology, Cell cultures, Chromatin, DNA binding proteins, Expression systems, Gene expression, Gene silencing, Genomics, Microbiology, Molecular virology, mRNA, nasopharyngeal carcinoma, next-generation sequencing, Oncogenes, Protein complexes, Transcription, Transcription factors, Transcriptional regulation, Virology, virus, virus replication

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Dr Steve Sweet
Senior Research Fellow
S.M.Sweet@sussex.ac.uk

Research interests: Bioinformatic tools for proteomics, Chromatin, DNA damage and repair, DNA double-strand breaks, Epigenetics, Histones, Mass Spectrometry, Protein identification, Protein-protein interactions, Proteomics, Transcription

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Dr Felicity Watts
Reader in Biochemistry
F.Z.Watts@sussex.ac.uk

Research interests: 53BP1, DNA repair, DNA replication, fission yeast, PCNA, Recombination, S. pombe, SUMO, Ubiquitin

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Prof Michelle West
Professor of Tumour Virology
M.J.West@sussex.ac.uk

Research interests: B cells, Cancer cell biology, Cell cycle, Chromatin, Epigenetics, Transcriptional regulation, Translational regulation, Virology

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Careers and perspectives

Our training courses equip you with the knowledge for scientific careers in academia, industry and scientific publishing. A research degree will give you a range of transferable skills that will be valuable in your chosen career. Our graduates have secured posts as science teachers, university lecturers and as researchers within the pharmaceutical industry. Many of our graduates go on to postdoctoral research posts within the UK and worldwide.

To find out more, visit Careers and alumni

Research training

The University’s Doctoral School runs a wide range of training courses covering the needs of students throughout all phases of their studies.

Visit the Doctoral School website

Visit Stages of doctoral study

School and contacts

Contact us

Postgraduate Admissions,
School of Life Sciences, 
John Maynard Smith Building, 
University of Sussex, Falmer, 
Brighton BN1 9QG, UK 
T +44 (0)1273 678057 
E lifesci@sussex.ac.uk

Visit the MRC Genome Damage and Stability Centre

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Our online campus tour can also give you an excellent introduction to the University.

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Meet with Sussex staff in your country at exhibitions, visits to schools and universities, and at a wide range of other events. Forthcoming visits are planned all over the world:

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In-country representatives

In the International Office, we manage a network of overseas representatives who have been trained to support international students with their application to study at the University. Services representatives provide can include pre-departure information, support in submitting your housing application and advice regarding applying for a UK Student Visa.

Find out more about our overseas visits and in-country representatives

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