Life Sciences

Combating Disease

Module code: C7140
Level 5
15 credits in spring teaching
Teaching method: Lecture, Laboratory, Post-lab
Assessment modes: Unseen examination, Coursework

In this module, you cover the basic concepts that are essential for a first understanding of contemporary aspects of cellular and molecular immunology, at the same time expanding on the modes of action of a range of common therapeutic agents, in terms of their modes of action, receptor/drug targets and associated physiological responses.

You discuss the role of innate and adaptive immunity in defence mechanisms, explaining how the innate immunity is able to recognise non-self-antigens and the meaning of inflammation.

Emphasis is given to how the structures of the antibody classes are related to their function and how antibody diversity and T-cell receptor diversity are generated. You review the structure and function of T-cells receptor and major histocompatibility complex. In order to understand T-cell activation, you cover antigens processing & presentation and the function of cytokines networks. Particular emphasis is given to how cell mediated and humoral immune responses are coordinated.

You also cover:

  • antibiotics and their mode of action
  • adrenergic transmission and the use of sympathomimetic agonist and antagonists
  • the cardiovascular system and the regulation of blood pressure by the renin angiotensin-aldosterone system.

Module learning outcomes

  • Display a sound knowledge and understanding of the major factors in the innate and adaptive immune responses and discuss how they are regulated and coordinated to defend the host
  • Discuss the mechanism of action and use of a variety of drugs in the treatment of diseases with immunological basis.
  • Gather, analyse and interpret data from experimental immunology and source material from both primary and secondary literature and be able to present a coherent scientific argument based upon this.