Life Sciences

Combating Disease

Module code: C7140
Level 5
15 credits in spring semester
Teaching method: Lecture, Laboratory, Post lab
Assessment modes: Coursework, Unseen examination

You'll cover the basic concepts that are essential for a first understanding of contemporary aspects of cellular and molecular immunology at the same time expanding on the modes of action of a range of common therapeutic agents, in terms of their modes of action, receptor/drug targets and associated physiological responses.

You'll discuss the role of innate and adaptive immunity in defense mechanisms, and learn how the innate immunity is able to recognise non-self-antigens and the meaning of inflammation.

Emphasis will be given to how the structures of the antibody classes are related to their function and how antibody diversity and T-cell receptor diversity are generated.

The structure and function of T-cells receptor and major histocompatibility complex will be reviewed. In order to understand T-cell activation, antigens processing and presentation and the function of cytokines networks will be covered. Particular emphasis will be given to how cell mediated and humoral immune responses are coordinated.

You'll also cover:

  • antibiotics and their mode of action
  • adrenergic transmission and the use of sympathomimetic agonist and antagonists
  • the cardiovascular system and the regulation of blood pressure by the renin angiotensin-aldosterone system.

Module learning outcomes

  • Display a sound knowledge and understanding of the major factors in the innate and adaptive immune responses and discuss how they are regulated and coordinated to defend the host
  • Discuss the mechanism of action and use of a variety of drugs in the treatment of diseases with immunological basis.
  • Gather, analyse and interpret data from experimental immunology and source material from both primary and secondary literature and be able to present a coherent scientific argument based upon this.