Module code: C7140
15 credits in spring teaching
Teaching method: Lecture, Laboratory, Post-lab
Assessment modes: Unseen examination, Coursework
In this module, you cover the basic concepts that are essential for a first understanding of contemporary aspects of cellular and molecular immunology, at the same time expanding on the modes of action of a range of common therapeutic agents, in terms of their modes of action, receptor/drug targets and associated physiological responses.
You discuss the role of innate and adaptive immunity in defence mechanisms, explaining how the innate immunity is able to recognise non-self-antigens and the meaning of inflammation.
Emphasis is given to how the structures of the antibody classes are related to their function and how antibody diversity and T-cell receptor diversity are generated. You review the structure and function of T-cells receptor and major histocompatibility complex. In order to understand T-cell activation, you cover antigens processing & presentation and the function of cytokines networks. Particular emphasis is given to how cell mediated and humoral immune responses are coordinated.
You also cover:
- antibiotics and their mode of action
- adrenergic transmission and the use of sympathomimetic agonist and antagonists
- the cardiovascular system and the regulation of blood pressure by the renin angiotensin-aldosterone system.
Module learning outcomes
- Display a sound knowledge and understanding of the major factors in the innate and adaptive immune responses and discuss how they are regulated and coordinated to defend the host
- Discuss the mechanism of action and use of a variety of drugs in the treatment of diseases with immunological basis.
- Gather, analyse and interpret data from experimental immunology and source material from both primary and secondary literature and be able to present a coherent scientific argument based upon this.