Photo of Neil Crickmore

Neil Crickmore
Senior Lecturer in Molecular Genetics (Biochemistry)
E:
T: +44 (0)1273 678917


Selected publications

Article

Shu, Changlong, Zhang, Fengjiao, Chen, Guihua, Joseph, Lazarus, Barqawi, Amina, Evans, Jacob, Song, Fuping, Li, Guoxun, Zhang, Jie and Crickmore, Neil (2017) A natural hybrid of a Bacillus thuringiensis Cry2A toxin implicates Domain I in specificity determination. Journal of Invertebrate Pathology, 150. pp. 35-40. ISSN 0022-2011

Noor-ul-Ane, M, Ali Mirhosseini, M, Crickmore, Neil, Saeed, S, Noor, I and Zalucki, M P (2017) Temperature-dependent development of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) and its larval parasitoid, Habrobracon hebetor (Say) (Hymenoptera: Braconidae): implications for species interactions. Bulletin of Entomological Research. ISSN 0007-4853

Badshah, Hayat, Ullah, Farman, Zada, Hayat, Zeb, Qamar, Shah, Ruidar A, Calatayud, Paul-André and Crickmore, Neil (2017) Comparison of Phenacoccus solenopsis specimens from different regions of Pakistan using COI molecular barcoding (Hemiptera: Pseudococcidae). Annales de la Societe Entomologique de France. ISSN 0037-9271

Krishnan, Vidisha, Domanska, Barbara, Elhigazi, Alicia, Afolabi, Fatai, West, Michelle J and Crickmore, Neil (2017) The human cancer cell active toxin Cry41Aa from Bacillus thuringiensis acts like its insecticidal counterparts. Biochemical Journal, 474 (10). pp. 1591-1602. ISSN 0264-6021

Adalat, Rooma, Saleem, Faiza, Crickmore, Neil, Naz, Shagufta and Shakoori, Abdul Rauf (2017) In vivo crystallization of three-domain cry toxins. Toxins, 9 (3). a80. ISSN 2072-6651

Jurat-Fuentes, Juan Luis and Crickmore, Neil (2017) Specificity determinants for Cry insecticidal proteins: insights from their mode of action. Journal of Invertebrate Pathology, 142. pp. 5-10. ISSN 0022-2011

Berry, Colin and Crickmore, Neil (2017) Structural classification of insecticidal proteins – towards an in silico characterization of novel toxins. Journal of Invertebrate Pathology, 142. pp. 16-22. ISSN 0022-2011

Badshah, Hayat, Ullah, Farman, Calatayud, Paul Andre and Crickmore, Neil (2016) Host stage preference and parasitism behaviour of Aenasius bambawaleian an encyrtid parasitoid of Phenacoccus solenopsis. Biocontrol Science and Technology, 26 (12). pp. 1605-1616. ISSN 0958-3157

Zhang, Fengjiao, Shu, Changlong, Crickmore, Neil, Li, Yanqiu, Song, Fuping, Liu, Chunqin, Chen, Zhibao and Zhang, Jie (2016) Use of redundant exclusion PCR to identify a novel Bacillus thuringiensis Cry8 toxin gene from pooled genomic DNA. Applied and Environmental Microbiology, 82 (13). pp. 3808-3815. ISSN 0099-2240

Crickmore, Neil (2016) Bacillus thuringiensis resistance in Plutella – too many trees? Current Opinion in Insect Science, 15. pp. 85-88. ISSN 2214-5753

Shu, Changlong, Zhou, Jianqiao, Crickmore, Neil, Li, Xianchun, Song, Fuping, Liang, Gemei, He, Kanglai, Huang, Dafang and Zhang, Jie (2016) In vitro template-change PCR to create single crossover libraries: a case study with B. thuringiensis Cry2A toxins. Scientific Reports, 6. p. 23536. ISSN 2045-2322

Ayra-Pardo, C, Raymond, B, Gulzar, A, Rodríguez-Cabrera, L, Morán-Bertot, Ivis, Crickmore, Neil and Wright, Dennis J (2015) Novel genetic factors involved in resistance to Bacillus thuringiensis in Plutella xylostella. Insect molecular biology, 24 (6). pp. 589-600. ISSN 0962-1075

Ruan, Lifang, Crickmore, Neil and Sun, Ming (2015) Is there sufficient evidence to consider Bacillus thuringiensis a multihost pathogen? Response to Loguercio and Argôlo-Filho. Trends in Microbiology, 23 (10). p. 587. ISSN 0966-842X

Ruan, Lifang, Crickmore, Neil, Peng, Donghai and Sun, Ming (2015) Are nematodes a missing link in the confounded ecology of the entomopathogen Bacillus thuringiensis? Trends in Microbiology, 23 (6). pp. 341-346. ISSN 0966-842X

Carrière, Yves, Crickmore, Neil and Tabashnik, Bruce E (2015) Optimizing pyramided transgenic Bt crops for sustainable pest management. Nature Biotechnology, 33 (2). pp. 161-168. ISSN 1087-0156

Abbas, Naeem, Crickmore, Neil and Shad, Sarfraz Ali (2015) Efficacy of insecticide mixtures against a resistant strain of house fly (Diptera: Muscidae) collected from a poultry farm. International Journal of Tropical Insect Science, 36 (1). pp. 48-53. ISSN 1742-7584

Badshah, Hayat, Ullah, Farman, Farid, Abid, Calatayud, Paul Andre and Crickmore, Neil (2015) Toxicity of Neem seed Azadirachta indica Juss (Meliaceae) different solvents extracts against cotton mealybug Phenacoccus solenopsis Tinsley (Sternorrhyncha: Pseudococcidae) under Laboratory conditions. Journal of Entomology and Zoology Studies, 3 (4). pp. 45-49. ISSN 2349-6800

Zhang, Wenfei, Zhang, Jie, Crickmore, Neil, Wu, Zhongqi, Yang, Yiran, Qian, Jiangzhao, Wu, Hongping, Wang, Ruiping and Fang, Xuanjun (2014) Identification of a mosquitocidal toxin from Bacillus thuringiensis using mass spectrometry. World Journal of Microbiology and Biotechnology, 30 (12). pp. 3273-3277. ISSN 0959-3993

De Bortoli, Caroline P, Polanczyk, Ricardo A, Crickmore, Neil, Vacari, Alessandra M and De Bortoli, Sergio A (2014) The investigation of factors potentially affecting the susceptibility of native Plutella xylostella populations to Bacillus thuringiensis cry toxins. International Journal of Agriculture Innovations and Research, 3 (3). pp. 823-832. ISSN 2319-1473

Li, Ying, Shu, Changlong, Zhang, Xuewen, Crickmore, Neil, Liang, Gemei, Jiang, Xingfu, Liu, Rongmei, Song, Fuping and Zhang, Jie (2014) Mining rare and ubiquitous toxin genes from a large collection of Bacillus thuringiensis strains. Journal of Invertebrate Pathology, 122C. pp. 6-9. ISSN 0022-2011

Bi, Yang, Zhang, Yanrui, Shu, Changlong, Crickmore, Neil, Wang, Qinglei, Du, Lixin, Song, Fuping and Zhang, Jie (2014) Genomic sequencing identifies novel Bacillus thuringiensis Vip1/Vip2 binary and Cry8 toxins that have high toxicity to Scarabaeoidea larvae. Applied Microbiology and Biotechnology. ISSN 0175-7598

Shan, Yueming, Shu, Changlong, Crickmore, Neil, Liu, Chunqin, Xiang, Wensheng, Song, Fuping and Zhang, Jie (2014) Cultivable gut bacteria of scarabs (Coleoptera: Scarabaeidae) inhibit Bacillus thuringiensis multiplication. Environmental Entomology, 43 (3). pp. 612-6. ISSN 1938-2936

Raymond, Ben, Wright, Denis J, Crickmore, Neil and Bonsall, Michael B (2013) The impact of strain diversity and mixed infections on the evolution of resistance to Bacillus thuringiensis. Proceedings of the Royal Society B: Biological Sciences, 280 (1769). p. 20131497. ISSN 0962-8452

Shu, Changlong, Zhang, Jingtao, Chen, Guihua, Liang, Gemei, He, Kanglai, Crickmore, Neil, Huang, Dafang, Zhang, Jie and Song, Fuping (2013) Use of a pooled clone method to isolate a novel Bacillus thuringiensis Cry2A toxin with activity against Ostrinia furnacalis. Journal of Invertebrate Pathology, 114 (1). pp. 31-33. ISSN 0022-2011

Singaravelu, B, Crickmore, N, Srikanth, J, Hari, K, Sankaranarayanan, C, Nirmala, R, Radesh Krishnan, S and Meghna, M (2013) Prospecting for scarabid specific Bacillus thuringiensis crystal toxin cry8 gene in sugarcane ecosystem of Tamil Nadu, India. Journal of Sugarcane Research, 3 (2). pp. 141-144. ISSN 2249-927X

Hernández-Martínez, Patricia, Hernández-Rodríguez, Carmen Sara, Krishnan, Vidisha, Crickmore, Neil, Escriche, Baltasar and Ferré, Juan (2012) Lack of Cry1Fa binding to the midgut brush border membrane in a resistant colony of Plutella xylostella moths with a mutation in the ABCC2 locus. Applied and Environmental Microbiology, 78 (18). pp. 6759-6761. ISSN 0099-2240

Ye, Weixing, Zhu, Lei, Liu, Yingying, Crickmore, Neil, Peng, Donghai, Ruan, Lifang and Sun, Ming (2012) Mining new crystal protein genes from Bacillus thuringiensis on the basis of mixed plasmid-enriched genome sequencing and a computational pipeline. Applied and Environmental Microbiology, 78 (14). pp. 4795-4801. ISSN 0099-2240

Zhang, Wenfei, Crickmore, Neil, George, Zenas Okon, Xie, Liu, He, Yong-Qiang, Li, Youzhi, Tang, Ji-Liang, Tian, Liang, Wang, Xi and Fang, Xuanjun (2012) Characterization of a new highly mosquitocidal isolate of Bacillus thuringiensis - an alternative to Bti? Journal of invertebrate pathology, 109 (2). pp. 217-222. ISSN 1096-0805

Crickmore, Neil, Badenes-Pérez, Francisco, Baxter, Simon, Heckel, David, Jiggins, Chris, Kain, Wendy, Morrison, Anna, Vogel, Heiko and Wang, Ping (2011) Parallel evolution of Bt toxin resistance in Lepidoptera. Genetics, 189 (2). pp. 675-679. ISSN 0016-6731

Raymond, Ben, Johnston, Paul R, Nielson-LeRoux, Christina, Lereclus, Didier and Crickmore, Neil (2010) Bacillus thuringiensis: an impotent pathogen? Trends in Microbiology, 18 (5). pp. 189-194. ISSN 0966-842X

Skov, L K, Seppala, U, Coen, J J F, Crickmore, N, King, T P, Monsalve, R, Kastrup, J S, Spangfort, M D and Gajhede, M (2006) Structure of recombinant Ves v 2 at 2.0 A resolution: structural analysis of an allergenic hyaluronidase from wasp venom. Acta Crystallographica Section D: Biological Crystallography, 62 (6). pp. 595-604. ISSN 0907-4449

Sayyed, Ali H, Gatsi, Roxani, Ibiza-Palacios, M. Sales, Escriche, Baltasar, Wright, Denis J and Crickmore, Neil (2005) Common, but complex, mode of resistance of Plutella xylostella to Bacillus thuringiensis toxins Cry1Ab and Cry1Ac. Applied and Environmental Microbiology, 71 (11). pp. 6863-6869. ISSN 0099-2240

Crickmore, Neil (2005) Using worms to better understand how Bacillus thuringiensis kills insects. Trends in Microbiology, 13 (8). pp. 347-350. ISSN 0966-842X

de Maagd, Ruud A, Bravo, Alejandra, Berry, Colin, Crickmore, Neil and Schnepf, H Ernest (2003) Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annual Review of Genetics, 37. pp. 409-433. ISSN 0066-4197

Bravo, Alejandra, Sánchez, Jorge, Kouskoura, Thaleia and Crickmore, Neil (2002) N-terminal activation is an essential early step in the mechanism of action of Bacillus thuringiensis Cry1Ac insecticidal toxin. Journal of Biological Chemistry, 277 (27). pp. 23985-23987. ISSN 0021-9258

Sayyed, Ali H, Gatsi, Roxani, Kouskoura, Thaleia, Wright, Denis J and Crickmore, Neil (2001) Susceptibility of a Field-Derived, Bacillus thuringiensis-Resistant Strain of Diamondback Moth to In Vitro-Activated Cry1Ac Toxin. Applied and Environmental Microbiology, 67 (9). pp. 4372-4373. ISSN 0099-2240

de Maagd, Ruud A, Bravo, Alejandra and Crickmore, Neil (2001) How Bacillus thuringiensis has evolved specific toxins to colonize the insect world. Trends in Genetics, 17 (4). pp. 193-199. ISSN 0168-9525

Sayyed, Ali H, Crickmore, Neil and Wright, Denis J (2001) Cyt1Aa from Bacillus thuringiensis subsp. israelensis is toxic to the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae) and synergizes the activity of Cry1Ac towards a resistant strain. Applied and Environmental Microbiology, 67 (12). pp. 5859-5861. ISSN 0099-2240

Book Section

Adang, Michael J, Crickmore, Neil and Jurat-Fuentes, Jual Luis (2014) Diversity of bacillus thuringiensis crystal toxins and mechanism of action. In: Dhadialla, Tarlochan and Gill, Sarjeet (eds.) Insect Midgut and Insecticidal Proteins. Advances in Insect Physiology, 47 . Academic Press, pp. 39-87.