Photo of Felicity Watts

Felicity Watts
Reader in Biochemistry (Genome Damage and Stability)
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T: +44 (0)1273 678257 or +44 (0)1273 877170


Selected publications

Article

Watts, Felicity Z (2016) Repair of DNA double-strand breaks in heterochromatin. Biomolecules, 6 (4). p. 47. ISSN 2218-273X

Jongjitwimol, Jirapas, Baldock, Robert A, Morley, Simon J and Watts, Felicity Z (2016) Sumoylation of eIF4A2 affects stress granule formation. Journal of Cell Science, 129 (12). pp. 2407-2415. ISSN 0021-9533

Densham, Ruth M, Garvin, Alexander J, Stone, Helen R, Strachan, Joanna, Baldock, Robert A, Daza-Martin, Manuel, Fletcher, Alice, Blair-Reed, Sarah, Beesley, James, Johal, Balraj, Pearl, Laurence H, Neely, Robert, Keep, Nicholas H, Watts, Felicity Z and Morris, Joanna R (2016) Human BRCA1-BARD1 ubiquitin ligase activity counters chromatin barriers to DNA resection. Nature Structural and Molecular Biology, 23. pp. 647-655. ISSN 1545-9993

Baldock, Robert A, Day, Matthew, Wilkinson, Oliver J, Cloney, Ross, Jeggo, Penelope A, Oliver, Antony W, Watts, Felicity Z and Pearl, Laurence H (2015) ATM localization and heterochromatin repair depend on Direct Interaction of the 53BP1-BRCT2 domain with γH2AX. Cell Reports, 13 (10). pp. 2081-2089. ISSN 2211-1247

Watts, Felicity Z, Baldock, Robert, Jongjitwimol, Jirapas and Morley, Simon J (2014) Weighing up the possibilities: controlling translation by ubiquitylation and sumoylation. Translation, 2 (2). e959366-1. ISSN 2169-074X

Garg, Mansi, Gurung, Resham L, Mansoubi, Sahar, Ahmed, Jubed O, Davé, Anoushka, Watts, Felicity Z and Bianchi, Alessandro (2014) Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association. EMBO Reports. ISSN 1469-3178

Jongjitwimol, Jirapas, Feng, Min, Zhou, Lihong, Wilkinson, Oliver, Small, Lauren, Baldock, Robert, Taylor, Deborah L, Smith, Duncan, Bowler, Lucas, Morley, Simon J and Watts, Felicity (2014) The S. pombe translation initiation factor eIF4G is sumoylated and associates with the SUMO protease Ulp2. PLoS ONE, 9 (5). e94182. ISSN 1932-6203

Watts, Felicity Z (2013) Starting and stopping SUMOylation. What regulates the regulator? Chromosoma, 122 (6). pp. 451-463. ISSN 0009-5915

Watts, Felicity Z and Hoffmann, Eva (2011) SUMO meets meiosis: an encounter at the synaptonemal complex: SUMO chains and sumoylated proteins suggest that heterogeneous and complex interactions lie at the centre of the synaptonemal complex. BioEssays, 33. pp. 529-33. ISSN 0265-9247

Boyd, L K, Mercer, B, Thompson, D, Main, E and Watts, F Z (2010) Characterisation of the SUMO-like domains of Schizosaccahromyces pombe Rad60. PLoS ONE, 5 (9). e13009. ISSN 1932-6203

Boyd, Lara K, Mercer, Brenda, Thompson, Darren, Main, Ewan and Watts, Felicity W (2010) Characterisation of the SUMO-like domains of Schizosaccharomyces pombe Rad60. PLoS ONE, 5 (9). pp. 1-11. ISSN 1932-6203

Watts, Felicity Z and Brissett, Nigel C (2010) Linking up and interacting with BRCT domains. DNA Repair, 9 (2). pp. 103-8. ISSN 1568-7864

Spirek, Mario, Estreicher, Anna, Csaszar, Edina, Wells, Jennifer, McFarlane, Ramsay J, Watts, Felicity Z and Loidl, Josef (2010) Sumoylation is required for normal development of linear element and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma, 9 (11). pp. 59-72. ISSN 0009-5915

Spirek, M, Estredicher, A, Csaszar, E, Wells, J, McFarlane, Ramsay J, Watts, Felicity and Loidl, J (2010) SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma, 119 (1). pp. 59-72. ISSN 1432-0886 (Electronic)

Skilton, Andrew, Outwin, Emily, Mercer, Brenda, Ho, J C Y and Watts, Felicity (2009) SUMO chain formation is required for response to replication arrest in S. pombe. PLoS ONE, 4 (8). e6750. ISSN 1932-6203

Kilkenny, Mairi L, Doré, Andrew S, Roe, S Mark, Nestoras, Konstantinos, Ho, Jenny C Y, Watts, Felicity Z and Pearl, Laurence H (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signalling. Genes and Development, 22 (15). pp. 2034-47. ISSN 0890-9369

Kilkenney, M L, Dore, A, Roe, S M, Nestoras, K, Ho, J, Watts, F Z and Pearl, L (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes and Development, 22 (15). pp. 2034-2047. ISSN 0890-9369

Watts, Felicity, Skilton, Andrew, Ho, J C, Boyd, Lara Katrina, Trickey, M A, Gardner, Lisa and Ogi, Francois-Xavier (2007) The role of Schizosaccharomyces pombe SUMO ligases in genome stability. Biochemical Society Transactions, 35 (6). pp. 1379-1384. ISSN 0300-5127

Watts, Felicity (2007) The role of SUMO in chromosome segregation. Chromosoma, 116 (1). pp. 15-20. ISSN 1432-0886

Frampton, Jonathan, Irmisch, Anja, Green, Catherine M, Neiss, Andrea, Trickey, Michelle, Ulrich, Helle D, Furuya, Kanji, Watts, Felicity, Carr, Antony M and Lehmann, Alan R (2006) Postreplication Repair and PCNA Modification in Schizosaccharomyces pombe. Molecular Biology of the Cell, 17 (7). pp. 2976-2985. ISSN 1059-1524

Watts, Felicity (2006) Sumoylation of PCNA: Wrestling with recombination at stalled replication forks. DNA Repair, 5 (3). pp. 399-403. ISSN 1568-7864

Shin, Jin, Choi, Eun Shik, Kim, Hyun Soo, Ho, J C, Watts, Felicity Z, Park, Sang D and Jang, Yeun Kyu (2005) SUMO modification is involved in the maintenance of heterochromatin stability in fission yeast. Molecular Cell, 19 (6). pp. 817-828. ISSN 1097-2765

Sergeant, John, Taylor, Elaine, Palecek, Jan, Fousteri, Maria, Andrews, Emily, Sweeney, Sara, Shinagawa, Hideo, Watts, Felicity and Lehmann, Alan (2005) Composition and Architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) Complex. Molecular and Cellular Biology, 25 (1). pp. 172-184. ISSN 0270-7306

Andrews, Emily A, Palecek, Jan, Sergeant, John, Taylor, Elaine, Lehmann, Alan R and Watts, Felicity Z (2005) Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Molecular and Cellular Biology, 25 (1). pp. 185-196. ISSN 0270-7306

Zhou, Lihong and Watts, Felicity (2005) Nep1, a Schizosaccharomyces pombe deneddylating enzyme. Biochemical Journal, 389 (Pt 2). pp. 307-314. ISSN 0264-6021

Spink, K, Ho, J C, Tanaka, K, Watts, Felicity and Chambers, Anna (2005) The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast. Biochemical Genetics, 43 (3-4). pp. 103-17. ISSN 0006-2928

Watts, Felicity (2004) SUMO modification of proteins other than transcription factors. Seminars in Cell & Developmental Biology, 15 (2). pp. 211-220. ISSN 10849521

Ho, J C and Watts, Felicity (2003) Characterisation of SUMO conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant negative allele which severely reduces SUMO conjugation. Biochemical Journal, 21. ISSN 0264-6021

Hinks, J, Roe, Mark, Ho, J C, Watts, Felicity, Phelan, J, McAllister, M and Pearl, Laurence (2003) Expression, purification and preliminary X-ray analysis of the BRCT domain from Rhp9/Crb2. Acta Crystallographica Section D: Biological Crystallography, 59 (Pt 7). 1230-1233.. ISSN 0907-4449

Taylor, Deborah, Ho, Jenny, Oliver, Alejandro and Watts, Felicity (2002) Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease. Journal of Cell Science, 115 (6). pp. 1113-1122. ISSN 0021-9533

Ho, J C, Warr, N J, Shimizu, H and Watts, Felicity (2001) SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52. Nucleic Acids Research, 29 (20). pp. 4179-4186. ISSN 1362-4962