Psychopharmacology of human memory:

  • The neurochemical bases of memory: the role of the cholinergic neurotransmitter system in human information processing, with particular emphasis on nicotinic receptors
  • The neurochemical and behavioural effects of nicotine in adolescents, younger and older adults
  • The behavioural and neural impact of the APOE e4 polymorphism across the lifespan


(work supported by grants from the BBSRC, MRC and the Wellcome Trust)

Memory decline in Alzheimer's Disease and other functional brain disorders:

  • Longitudinal study of behavioural change in activities of daily living in people with DAT
  • Non-pharmacological interventions (eg Art Therapy) for older people with dementia
  • Eye movements in everyday memory
  • Cognitive deficits associated with heart disease in the over 60s
  • The effects of exercise and diet on age-related cognitive change and on rate of decline in people with dementia
  • A Pocket Book of Memories A memory aid for people with dementia., developed and published with Linda Sheppard. (Hawker Publications, 1999)

(work supported by grants from the Wellcome Trust, BBSRC, Brritish Academy, PPP Foundation, Brighton Heart Support Trust)