Photo of Youssra Al-Hilaly

Youssra Al-Hilaly
Post-Doctoral Research Fellow (Biochemistry)

Selected publications


Sampani, Stavroula L, Al-Hilaly, Youssra K, Malik, Sharali, Serpell, Louise C and Kostakis, George E (2019) Zinc-dysprosium functionalized amyloid fibrils. Dalton Transactions. ISSN 1477-9226 (Accepted)

Raulin, Ana-Caroline, Kraft, Lucas, Al-Hilaly, Youssra, Xue, Wei-Feng, McGeehan, John E, Atack R, John and Serpell, Louise (2019) The molecular basis for apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease. Journal of Molecular Biology. ISSN 0022-2836

Fichou, Yann, Al-Hilaly, Youssra K, Devred, François, Smet-Nocca, Caroline, Tsvetkov, Philipp O, Verelst, Joke, Winderickx, Joris, Geukens, Nick, Vanmechelen, Eugeen, Perrotin, Audrey, Serpell, Louise, Hanseeuw, Bernard J, Medina, Miguel, Buée, Luc and Landrieu, Isabelle (2019) The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention? Acta Neuropathologica Communications, 7 (31). pp. 1-17. ISSN 2051-5960

Al-Hilaly, Youssra K, Pollack, Saskia J, Rickard, Janet E, Simpson, Michael, Raulin, Ana-C, Baddeley, Thomas, Schellenberger, Pascale, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2018) Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT). Journal of Molecular Biology, 430 (21). pp. 4119-4131. ISSN 0022-2836

Al-Hilaly, Youssra K, Pollack, Saskia J, Vadukul, Devkee, Citossi, Francesca, Rickard, Janet E, Simpson, Michael, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2017) Alzheimer's disease-like paired helical filament assembly from truncated tau protein is independent of disulphide cross-linking. Journal of Molecular Biology, 429 (4). pp. 3650-3665. ISSN 0022-2836

Al-Hilaly, Youssra K, Biasetti, Luca, Brakeman, Ben J, Pollack, Saskia J, Zibaee, Shahin, Abdul-Sada, Alaa, Thorpe, Julian R, Xue, Wei-Feng and Serpell, Louise C (2016) The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease. Scientific Reports, 6. p. 39171. ISSN 2045-2322

Marshall, Karen E, Vadukul, Devkee M, Dahal, Liza, Theisen, Alina, Fowler, Milena W, Al-Hilaly, Youssra, Ford, Lenzie, Kemenes, György, Day, Iain J, Staras, Kevin and Serpell, Louise (2016) A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration. Scientific Reports, 6. ISSN 2045-2322

Bukar Maina, Mahmoud, Al-Hilaly, Youssra and Serpell, Louise (2016) Nuclear tau and its potential role in Alzheimer’s disease. Biomolecules, 6 (1). 9 1-20. ISSN 2218-273X

Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William, Morris, Kyle L, Sada, Alaa, Thorpe, Julian R and Serpell, Louise C (2013) A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease. Acta Neuropathologica Communications, 1 (83). pp. 1-17. ISSN 2051-5960

Book Section

Vadukul, Devekee M, Al-Hilaly, Youssra K and Serpell, Louise C (2018) Methods for structural analysis of amyloid fibrils in misfolding diseases. In: Gomes, Cláudio M (ed.) Protein misfolding diseases. Humana Press, New York, NY, pp. 109-122. ISBN 9781493988198


Al-Hilaly, Youssra Kareem (2014) Chemical and biochemical studies of dityrosine cross-link formation in amyloidogenic peptides. Doctoral thesis (PhD), University of Sussex.