Selected publications

Article

Ottolini, Christian S, Capalbo, Antonio, Newnham, Louise, Cimadomo, Danilo, Natesan, Senthilkumar A, Hoffmann, Eva R, Ubaldi, Filippo M, Rienzi, Laura and Handyside, Alan H (2016) Generation of meiomaps of genome-wide recombination and chromosome segregation in human oocytes. Nature protocols, 11 (7). pp. 1229-43. ISSN 1750-2799

Ottolini, Christian S, Newnham, Louise J, Capalbo, Antonio, Natesan, Senthilkumar A, Joshi, Hrishikesh A, Cimadomo, Danilo, Griffin, Darren K, Sage, Karen, Summers, Michael C, Thornhill, Alan R, Housworth, Elizabeth, Herbert, Alex D, Rienzi, Laura, Ubaldi, Filippo M, Handyside, Alan H and Hoffmann, Eva R (2015) Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates. Nature Genetics, 47. pp. 727-735. ISSN 1061-4036

Gallina, Irene, Colding, Camilla, Henriksen, Peter, Beli, Petra, Nakamura, Kyosuke, Offman, Judith Muriel, Mathiasen, David, Silva, Sonia, Hoffmann, Eva, Groth, Anja, Choudhary, Chunaram and Lisby, Michael (2015) Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nature Communications, 6. p. 6533. ISSN 2041-1723

Herbert, Alex D, Carr, Antony M and Hoffmann, Eva (2014) FindFoci: a focus detection algorithm with automated parameter training that closely matches human assignments, reduces human inconsistencies and increases speed of analysis. PLoS ONE, 9 (12). e114749. ISSN 1932-6203

Newnham, Louise, Jordan, Philip W, Carballo, Jesus A, Newcombe, Sonya and Hoffmann, Eva (2013) Ipl1/aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis. PLoS ONE, 8 (12). e83982. ISSN 1932-6203

Copsey, Alice, Tang, Shangming, Jordan, Philip W, Blitzblau, Hannah, Newcombe, Sonya, Chan, Andrew Chi-ho, Newnham, Louise, Li, Zhaobo, Gray, Steve, Herbert, Alex, Arumugam, Prakash, Hochwagen, Andreas, Hunter, Neil and Hoffmann, Eva (2013) Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic division. PLoS Genetics, 9 (12). e1004071. ISSN 1553-7390

Newcombe, Sonya, Bobin, Mariusz, Shrikhande, Amruta, Gallop, Chris, Pace, Yannick, Yong, Helen, Gates, Rebecca, Chaudhuri, Shuvashri, Roe, Mark, Hoffmann, Eva and Viseux, Eddy M E (2013) Gold amides as anticancer drugs: synthesis and activity studies. Organic and Biomolecular Chemistry, 19 (11). pp. 3255-3260. ISSN 1477-0520

Hoffmann, Eva (2011) Chromosome Recombination. Seminars in Cell and Developmental Biology, 22 (8). p. 865. ISSN 1084-9521

Watts, Felicity Z and Hoffmann, Eva (2011) SUMO meets meiosis: an encounter at the synaptonemal complex: SUMO chains and sumoylated proteins suggest that heterogeneous and complex interactions lie at the centre of the synaptonemal complex. BioEssays, 33. pp. 529-33. ISSN 0265-9247

Gatz, Susanne A, Ju, Limei, Gruber, Ralph, Hoffmann, Eva, Carr, Antony M, Wang, Zhao-Qi, Liu, Cong and Jeggo, Penny A (2011) Requirement for DNA Ligase IV during Embryonic Neuronal Development. Journal of Neuroscience, 31. pp. 10088-100100.

Cotton, Victoria E, Hoffmann, Eva R and Borts, Rhona H (2010) Distinct regulation of Mlh1p heterodimers in meiosis and mitosis in Saccharomyces cerevisiae. Genetics, 185. pp. 459-467. ISSN 0016-6731

Falk, Jill E, Chan, Andrew Chi-ho, Hoffmann, Eva and Hochwagen, Andreas (2010) A Mec1- and PP4-dependent checkpoint couples centromere pairing to meiotic recombination. Developmental Cell, 19. pp. 599-611. ISSN 1534-5807

Newnham, Louise, Jordan, Philip, Rockmill, Beth, Roeder, G Shirleen and Hoffmann, Eva (2010) The synaptonemal complex protein, Zip1 promotes the segregation of nonexchange chromosomes at meiosis I. Proceedings of the National Academy of Sciences, 107 (2). pp. 781-785. ISSN 1091-6490

Jordan, P, Copsey, A, Newnham, L, Kolar, E, Lichten, M. and Hoffmann, Eva (2009) Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis. Genes and Development, 23. pp. 2237-2251. ISSN 0890-9369

Jordan, Philip, Copsey, Alice, Newnham, Louise, Kolar, E., Lichten, M. and Hoffmann, Eva (2009) Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis. Genes and Development, 23 (18). pp. 2237-2251. ISSN 0890-9369

Clyne, M, Offman, J, Shanley, S, Virgo, J D, Radulovic, M, Wang, Y, Ardern-Jones, A, Eeles, R, Hoffman, E, Yu, V P C C and Unset (2009) The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome. British Journal of Cancer. ISSN 0007-0920

Jordan, Philip, Copsey, Alice, Newnham, Louise, Kolar, Eizabeth, Michael, Lichten and Hoffmann, Eva (2009) Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis. Genes and Development, 23 (18). pp. 2237-2251. ISSN 0890-9369

Chan, Andrew Chi-ho, Borts, Rhona H and Hoffmann, Eva (2009) Temperature-dependent modulation of interference and chromosome segregation in msh4 mutants of budding yeast. PLoS ONE, 4. e7284. ISSN 1932-6203

Hoffmann, Eva R, Eriksson, Emma, Herbert, Benjamin J and Borts, Rhona H (2005) MLH1 and MSH2 promote the symmetry of double-strand break repair events at the HIS4 hotspot in Saccharomyces cerevisiae. Genetics, 169. pp. 1291-1303. ISSN 0016-6731

Hoffmann, Eva R and Borts, Rhona H (2005) Trans Events Associated with Crossovers Are Revealed in the Absence of Mismatch Repair Genes in Saccharomyces cerevisiae. Genetics, 169. pp. 1305-1310. ISSN 0016-6731

Hoffmann, E R and Borts, R H (2004) Meiotic recombination intermediates and mismatch repair proteins. Cytogenetic and Genome Research, 107. pp. 232-248. ISSN 1424-859X

Abdullah, Mohammed F F, Hoffmann, Eva R, Cotton, V E and Borts, Rhona H (2004) A Role for MutL Homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast. Cytogenetic and Genome Research, 107. pp. 180-190.

Hoffmann, Eva R, Shcherbakova, Polina V, Kunkel, Thomas A and Borts, Rhona H (2003) MLH1 Mutations Differentially Affect Meiotic Functions in Saccharomyces cerevisiae. Genetics, 163 (2). pp. 515-526. ISSN 0016-6731

Hjorth-Sørensen, Bjørn, Hoffmann, Eva R, Lissin, Nikolai M, Sewell, Andrew K and Jakobsen, Bent K (2001) Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins. Molecular Microbiology, 39 (4). pp. 914-923. ISSN 0950-382X

Book Section

Hoffmann, Eva, Victoria, C, Rhona, B and Faiz, A (2009) The devil is in the details: The importance of genetic and environmental factors for yeast meiosis. In: Protocols for Meiosis. Unset.