Jessica Downs
Visiting Research Fellow (Genome Damage and Stability)
E:
T: +44 (0)1273 678369 or +44 (0)1273 877514

Selected publications

Article

Schalbetter, Stephanie, Mansoubi, Sahar, Chambers, Anna L., Downs, Jessica and Baxter, Jon (2015) Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability. PNAS.

Kakarougkas, Andreas, Ismail, Amani, Chambers, Anna, Riballo, Queti, Herbert, Alex, Kunzel, Julia, Lobrich, Markus, Jeggo, Penny and Downs, Jessica (2014) Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin. Molecular Cell, 55 (5). pp. 723-732. ISSN 1097-2765

Pal, Mohinder, Morgan, Marc, Phelps, Sarah E L, Roe, S Mark, Parry-Morris, Sarah, Downs, Jessica, Polier, Sigrun, Pearl, Laurence and Prodromou, Chrisostomos (2014) Structural basis for phosphorylation-dependent recruitment of tel2 to hsp90 by pih1. Structure, 22 (6). pp. 805-818. ISSN 1878-4186

Brownlee, Peter M, Chambers, Anna L, Cloney, Ross, Bianchi, Alessandro and Downs, Jessica A (2014) BAF180 promotes cohesion and prevents genome instability and aneuploidy. Cell Reports, 6 (6). pp. 973-981. ISSN 2211-1247

Chambers, Anna L, Pearl, Laurence H, Oliver, Antony W and Downs, Jessica A (2013) The BAH domain of Rsc2 is a histone H3 binding domain. Nucleic Acids Research, 41 (19). pp. 9168-9182. ISSN 0305-1048

Chambers, Anna L, Ormerod, Georgina, Durley, Samual C, Sing, Tina L, Brown, Grant W, Kent, Nicholas A and Downs, Jessica A (2012) The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes & Development, 26 (23). pp. 2590-2603. ISSN 0890-9369

Niimi, Atsuko, Chambers, Anna L, Downs, Jessica A and Lehmann, Alan R (2012) A role for chromatin remodellers in replication of damaged DNA. Nucleic Acids Research, 40 (15). pp. 7393-7403. ISSN 0305-1048

Brownlee, Peter M, Chambers, Anna L, Oliver, Antony W and Downs, Jessica A (2012) Cancer and the bromodomains of BAF180. Biochemical Society Transactions, 40 (2). pp. 364-369. ISSN 0300-5127

Chambers, Anna L and Downs, Jessica A (2012) The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair. Progress in molecular biology and translational science, 110. pp. 229-261. ISSN 1878-0814

Chambers, A L, Brownlee, P M, Durley, S C, Beacham, T, Kent, N A and Downs, J A (2012) The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses. PLoS ONE, 7 (2). e32016. ISSN 1932-6203

Foster, Elinor R and Downs, Jessica A (2009) Methylation of H3 K4 and K79 is not strictly dependent on H2B K123 ubiquitylation. Journal of Cell Biology, 184 (5). pp. 631-638. ISSN 0021-9525