Prof George Kemenes

Biography

Professor of Neuroscience (2005, Sussex)

PhD (Neuroscience, 1985, Budapest),  DSc (Biological Sciences, 1996, Budapest)

BSc (Biology, 1979, Budapest)

Role

Course convenor, MSc in Cellular and Molecular Neuroscience

Course convenor, Neural Circuits

Director of Doctoral Studies

In the use of classical invertebrate neuroethological experimental models (Aplysia, Helix, Lymnaea) for the investigation of the neuronal mechanisms underlying the generation and modulation of various types of behaviour, including learning. Cellular and molecular mechanisms of memory function and dysfunction. Technical expertise in behavioural analysis, electrophysiology, neuroanatomy, imaging and a variety of neuropharmacological and biochemical techniques.

Plasticity and Gene Regulation (BES Final Year course)

Advanced Techniques in Neuroscience (BES MSc course)

Transduction & Transmission (BES MSc Course)

Plasticity & Development (BES MSc Course)

Sensory Systems & Receptors (BES MSc Course)

Neuroscience & Behaviour (BSMS 2nd year course)

Neural Circuits (BES 2nd year course)

Functional Neuroanatomy (BES 2nd year course)

Cellular & Molecular Mechamisms of Learning and Memory (ERASMUS Teacher Exchange Programme with Hungary)

Nikitin, Evgeny S, Balaban, Pavel M and Kemenes, George (2013) Nonsynaptic plasticity underlies a compartmentalized increase in synaptic efficacy after classical conditioning. Current Biology, 23 (7). pp. 614-619. ISSN 0960-9822

Korneev, Sergei A, Kemenes, Ildiko, Bettini, Natalia L, Kemenes, George, Staras, Kevin, Benjamin, Paul and O'Shea, Michael (2013) Axonal trafficking of an antisense RNA transcribed from a pseudogene is regulated by classical conditioning. Scientific Reports, 3. pp. 1-5. ISSN 2045-2322

Samu, David, Marra, Vincenzo, Kemenes, Ildiko, Crossley, Michael, Kemenes, György, Staras, Kevin and Nowotny, Thomas (2012) Single electrode dynamic clamp with StdpC. Journal of Neuroscience Methods, 211 (1). pp. 11-21. ISSN 0165-0270

Harris, Christopher A, Buckley, Christopher L, Nowotny, Thomas, Passaro, Peter A, Seth, Anil K, Kemenes, György and O'Shea, Michael (2012) Multi-neuronal refractory period adapts centrally generated behaviour to reward. PLoS ONE, 7 (7). e42493. ISSN 1932-6203

Kemenes, Ildikó, Marra, Vincenzo, Crossley, Michael, Samu, Dávid, Staras, Kevin, Kemenes, György and Nowotny, Thomas (2011) Dynamic clamp with StdpC software. Nature Protocols, 6 (3). pp. 405-417. ISSN 1754-2189

Pirger, Zsolt, László, Zita, Hiripi, Laszlo, Hernadi, Laszlo, Tóth, Gábor, Lubics, Andrea, Reglődi, Dóra, Kemenes, György and Mark, Laszlo (2010) Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Its Receptors Are Present and Biochemically Active in the Central Nervous System of the Pond Snail Lymnaea stagnalis. Journal of Molecular Neuroscience, 42 (3). pp. 464-471. ISSN 0895-8696

Pirger, Z, Laszlo, Z, Hiripi, L, Reglodi, D, Lubics, A, Mark , L and Kemenes, G (2010) Memory, cAMP, and PACAP-a phylogenetically conserved function? Studies in Lymnea stagnalis. Journal of Molecular Neuroscience, 42 (3). p. 301. ISSN 0895-8696

Pirger, Zsolt, László, Zita, Kemenes, Ildikó, Tóth, Gábor, Reglődi, Dóra and Kemenes, György (2010) A Homolog of the Vertebrate Pituitary Adenylate Cyclase-Activating Polypeptide Is Both Necessary and Instructive for the Rapid Formation of Associative Memory in an Invertebrate. Journal of Neuroscience, 30 (41). pp. 13766-13773. ISSN 0270-6474

Harris, Christopher A, Passaro, Peter A, Kemenes, Ildikó, Kemenes, György and O'Shea, Michael (2010) Sensory driven multi-neuronal activity and associative learning monitored in an intact CNS on a multielectrode array. Journal of Neuroscience Methods, 186 (2). pp. 171-178. ISSN 0165-0270

Wan, Huimin, Mackay, Beth, Iqbal, Hassan, Naskar, Souvik and Kemenes, György (2010) Delayed intrinsic activation of an NMDA-independent CaM-kinase II in a critical time window is necessary for late consolidation of an associative memory. Journal of Neuroscience, 30 (1). pp. 56-63. ISSN 0270-6474

Kemenes, György (2009) Behavioral choice: a novel role for presynaptic inhibition of sensory Inputs. Current Biology, 19 (23). R1087-R1088. ISSN 0960-9822

Kemenes, György (2009) Learning and memory: how sea slug behaviors become compulsive. Current Biology, 19 (13). R515-R517. ISSN 0960-9822

Kiss, Tibor, Pirger, Zsolt and Kemenes, György (2009) Food-aversive classical conditioning increases a persistent sodium current in molluscan withdrawal interneurons in a transcription dependent manne. Neurobiology of Learning and Memory, 92 (1). pp. 114-119. ISSN 1074-7427

Benjamin, P R and Kemenes, G (2008) Invertebrate models to study learning and memory: Lymnaea. In: Encyclopedia of Neuroscience. Elsevier, pp. 197-204. ISBN 9780080450469

Michel, Maximilian, Kemenes, Ildikó, Müller, Uli and Kemenes, György (2008) Different phases of long-term associative memory require PKA activation in different time windows after a single learning trial. Learning & Memory, 15 (9). pp. 694-702. ISSN 1072-0502

Nikitin, Eugeny S, Vavoulis, Dimitris V, Kemenes, Ildikó, Marra, Vincenzo, Pirger, Zsolt, Michel, Maximilian, Feng, Jianfeng, O'Shea, Michael, Benjamin, Paul R and Kemenes, György (2008) Persistent Sodium Current Is a Nonsynaptic Substrate for Long-Term Associative Memory. Current Biology, 18 (16). pp. 1221-1226. ISSN 0960-9822

Nikitin, Eugeny S, Vavoulis, Dimitris V, Kemenes, Ildikó, Marra, Vincenzo, Pirger, Zsolt, Michel, Maximilian, Feng, Jianfeng, O'Shea, Michael, Benjamin, Paul R and Kemenes, György (2008) Persistent Sodium Current Is a Nonsynaptic Substrate for Long-Term Associative Memory. Current Biology, 18 (16). pp. 1221-1226. ISSN 0960-9822

Nikitin, Eugeny S, Vavoulis, Dimitris V, Kemenes, Ildikó, Marra , Vincenzo, Pirger, Zsolt, Michel, Maximillian, Feng, Jianfeng, O'Shea, Michael, Benjamin, Paul R and Kemenes, György (2008) Persistent sodium current is a non-synaptic substate for long-term associative memory. Current Biology, 18 (16). pp. 1221-1226. ISSN 0960-9822

Benjamin, Paul R, Kemenes, Ildikó and Kemenes, György (2008) Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs. Frontiers in Biosciences, 13. pp. 4051-4057. ISSN 1093-4715

Benjamin, P R and Kemenes, G (2008) Behavioral and circuit analysis of learning and memory in molluscs. In: Learning and Memory: A Comprehensive Reference. Elsevier, pp. 587-604. ISBN 9780123705044

Kemenes, G (2008) Molecular mechanisms of associative learning: lymnaea. In: Learning and memory: a comprehensive reference. Elsevier, pp. 133-148. ISBN 9780123705044

Vavoulis, Dimitris V, Nikitin, Eugeny S, Feng, Jianfeng, Benjamin, Paul R and Kemenes, György (2007) Computational model of a modulatory cell type in the feeding network of the snail, Lymnaea stagnalis. In: BMC Neuroscience.

Vavoulis, Dimitris V, Straub, Volko A, Kemenes, Ildikó, Kemenes, György, Feng, Jianfeng and Benjamin, Paul R (2007) Dynamic control of a central pattern generator circuit: a computational model of the snail feeding network. European Journal of Neuroscience, 25 (9). pp. 2805-2811. ISSN 0953-816X

Kemenes, György, Kemenes, Ildikó, Michel, Maximilian, Papp, Andrea and Mueller, Uli (2006) Phase-dependent molecular requirements for memory reconsolidation: differential roles for protein synthesis and protein kinase A activity. Journal of Neuroscience, 26 (23). pp. 6298-6302. ISSN 0270-6474

Hatakeyama, D, Sadamoto, H, Watanabe, T, Wagatsuma, A, Kobayashi, S, Fujito, Y, Yamashita, M, Sakakibara, M, Kemenes, G and Ito, E (2006) Requirement of new protein synthesis of a transcription factor for memory consolidation: paradoxical changes in mRNA and protein levels of C/EBP. Journal of Molecular Biology, 356 (3). pp. 569-577.

Nikitin, E S, Kiss, T, Staras, K, O'Shea, M, Benjamin, P R and Kemenes, G (2006) Persistent sodium current is a target for cAMP-induced neuronal plasticity in a state-setting modulatory interneuron. Journal of Neurophysiology, 95 (1). pp. 453-463. ISSN 0022-3077

Nikitin, Evgeny S, Zakharov, Igor S, Samarova, EIena I, Kemenes, György and Balaban, Pavel M (2005) Fine tuning of olfactory orientation behaviour by the interaction of oscillatory and single neuronal activity. European Journal of Neuroscience, 22 (11). pp. 2833-2844. ISSN 0953-816X

Ribeiro, M J, Schofield, M G, Kemenes, I, O'Shea, M, Kemenes, G and Benjamin, P R (2005) Activation of MAPK is necessary for long-term memory consolidation following food-reward conditioning. Learning & Memory, 12 (5). pp. 538-545.

Serfőző, Zoltán, Ribeiro, Maria J, Papp, Andrea, Kemenes, Ildikó, O'Shea, Michael, Yin, Jerry C P, Benjamin , Paul R and Kemenes, György (2003) Cyclic AMP response element binding (CREB)-like proteins in a molluscan brain: cellular localization and learning-induced phosphorylation. European Journal of Neuroscience, 18 (5). pp. 1223-1234. ISSN 1460-9568

Staras, Kevin, Kemenes, Ildikó, Benjamin, Paul R and Kemenes, György (2003) Loss of self-inhibition is a cellular mechanism for eipsodic rhythmic behavior. Current Biology, 13. pp. 116-124. ISSN 0960-9822

Serfőző, Zoltán, Veréb, Zoltán, Rőszer, Tamás, Kemenes, György and Elekes, Károly (2002) Development of the nitric oxide/cGMP system in the embryonic andjuvenile pond snail, Lymnaea stagnalis L. A comparative in situ hybridization, histochemical and immunohistochemical study. Journal of Neurocytology, 31 (2). pp. 131-147. ISSN 0300-4864

Korneev, Sergei A., Kemenes, Ildikó, Straub, Volko, Staras, Kevin, Korneeva, Elena I, Kemenes, György, Benjamin, Paul R and O'Shea, Michael (2002) Suppression of nitric oxide (NO)-dependent behavior by double-stranded RNA-mediated silencing of a neuronal NO synthase gene. Journal of Neuroscience, 22 (11). pp. 227-331. ISSN 0270-6474

Jones, Nick, Kemenes, György and Benjamin, Paul R (2001) Selective expression of electrical correlates of differential appetitive classical conditioning in a feeding network. Journal of Neurophysiology, 85 (1). pp. 89-97. ISSN 0022-3077

Staras, Kevin, Kemenes, György and Benjamin, Paul R (1999) Electrophysiological and behavioural analysis of lip touch as a component of the food stimulus in unconditioned feeding of the snail Lymnaea. Journal of Neurophysiology, 81 (3). pp. 1261-1273. ISSN 0022-3077

Staras, Kevin, Kemenes, György and Benjamin, Paul R (1998) Neurophysiological correlates of unconditioned and conditioned feeding behaviour in the pond snail Lymnaea stagnalis. Journal of Neurophysiology, 79 (6). pp. 3030-3040. ISSN 0022-3077

Kemenes, György, Staras, Kevin and Benjamin, Paul R (1997) In vitro appetitive classical conditioning of the feeding response in the pond snail Lymnaea stagnalis. Journal of Neurophysiology, 78 (5). pp. 2351-2362. ISSN 00223077